Publications by authors named "U A Ansari"

Background: The American Association of Hip and Knee Surgeons (AAHKS) strongly recommends the use of dexamethasone in patients undergoing total joint arthroplasty (TJA) due to its therapeutic effects. However, use in diabetic patients is controversial due to safety. Therefore, the objective of this study was to determine safety: (1) calculating the post-operative glucose levels; (2) finding the ideal dexamethasone dosing regimen; and (3) reporting complications of dexamethasone administration in diabetic patients undergoing TJA.

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  • Ventricular premature depolarizations (VPDs) during acute coronary syndrome (ACS) correlate with increased hospital mortality, particularly with RBBB patterns.* -
  • In a study involving 18,009 ACS patients, 627 with VPDs showed a higher hospital mortality rate (7.8%) compared to those without (4.9%).* -
  • The presence of RBBB pattern in VPDs is linked to higher hospital mortality, while VPDs with a superior axis are associated with increased post-discharge mortality.*
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  • - Acquired factor V (FV) inhibitors are rare conditions with symptoms ranging from mild lab abnormalities to serious bleeding events, making diagnosis difficult due to the variety of presentations.
  • - There is no established standard treatment for these inhibitors, and most patients in studies receive a mix of immunosuppressive therapies and recombinant products.
  • - A case study of a man in his 50s showed that after initial treatments only led to slight improvement, he experienced better results with weeks of rituximab in combination with glucocorticoids, suggesting rituximab might be a viable treatment option for this condition.
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Objective: Selective androgen receptor modulators (SARMs) are potential treatments for ameliorating age-related physical dysfunctions caused by sarcopenia, cachexia and chronic illnesses such as cancer. The purpose of this systematic review is to analyse the effect of SARMs on physical performance and body and evaluate their safety profile.

Methods: A systematic review search criteria following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines was performed in three databases for studies reporting physical parameter outcomes after SARM intervention.

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Nicotinamide adenine dinucleotide (NAD+) is essential in the proper function of many essential cellular processes in the human body. The purpose of this review is to investigate the effect of nicotinamide mononucleotide (NMN), a NAD+ precursor, on physical performance and evaluate the safety profile of supplementation. A systematic review search criteria following the guidelines from the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) was performed in four databases for randomized controlled trials on NMN supplementation.

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