Publications by authors named "Tzvetanka D Dimitrova Dinkova"
Article Synopsis
- MicroRNAs (miRNAs) are small non-coding RNAs that help control gene expression by affecting mRNA stability and translation, with their levels varying based on developmental stages and stress conditions.
- Researchers observed that starving early L4 larvae of C. elegans for 12 hours led to physical changes like reduced size and lipid content, along with increased lifespan, prompting an investigation into how miRNA expression alters during starvation.
- The study found that 13 miRNAs were upregulated and 2 downregulated in starved larvae; specifically, the miR-35 family showed significant increases, correlating with decreased levels of its target gene gld-1, which is notable for its role in reproduction.
