Differences in Cardiopulmonary Fitness Between Boy and Girls With Repaired Tetralogy of Fallot.

Objective: Many studies have demonstrated that patients with repaired tetralogy of Fallot (rTOF) have generally poorer cardiopulmonary fitness (CPF). However, little is known about how the disease results in different CPF in each sex. Therefore, this study aimed to investigate whether sex (and gender) differences affect CPF in children and adolescents with rTOF.

Differences between Sexes in Cardiopulmonary Fitness among Children and Adolescents with Kawasaki Disease.

It is known that children and adolescents with Kawasaki disease (KD) can maintain normal cardiopulmonary fitness (CPF) after the disease's acute stage has subsided. This study aimed to investigate whether gender differences affect CPF in children and adolescents with KD. We retrospectively reviewed a cohort of 204 participants (120 boys and 84 girls) with KD.

Addition of benzyl ethers to alkynes: a metal-free synthesis of 1-isochromenes.

Bromotrimethylsilane (TMSBr)-promoted intramolecular cyclization of (-arylethynyl)benzyl ethers to form 1-isochromenes at room temperature is reported. Further studies indicated that vinyl carbocations are the reaction intermediates which are stabilized by the conjugated aryl groups. Thus, -addition of benzyl ethers/tetrahydropyrans to alkynes was achieved under metal-free, acidic conditions.

Synthesis of 2-Aryl Acetophenones via Hydrobromination and Oxy-isomerization of (-Arylethynyl)benzyl Alcohols.

Hydrobromination and oxy-isomerization of (-arylethynyl)benzyl alcohols to yield brominated aryl ketones were achieved with bromotrimethylsilane. The substrate scope suggested that vinyl carbocations, stabilized by the conjugated aryl groups, are the reaction intermediates. 1-Isochromene was also detected by H NMR, and an isolated 1-isochromene was converted to the product when retreated with TMSBr.