Publications by authors named "Tzu -Yen Chang"

Hyperbaric oxygen (HBO) therapy has emerged as a potential treatment, shown to enhance blood flow and angiogenesis. However, specific effects and mechanisms of HBO on limb ischaemia responding to a hypoxic environment remain largely unknown. We aimed to investigate the therapeutic potential of HBO in the treatment of limb ischaemia.

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  • A systematic review and meta-analysis were conducted to evaluate the effectiveness of extended antibiotic prophylaxis (EAP) in preventing surgical site infections (SSI) after surgery, given mixed results in previous research.
  • The analysis included 14 studies with 12,572 patients, assessing the impact of EAP compared to no extended treatment on SSI risks, using risk ratios for evaluation.
  • Findings indicated that EAP did not significantly reduce the risk of SSI in patients undergoing implant-based breast reconstruction after mastectomy.
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Background: Capsular contracture is the most common reason for having a secondary breast implant operation. The failure of the implanted device and discomfort are related to foreign body response, which involves a pathologic encapsulation. An up-regulated expression of CD248 was previously demonstrated to modulate inflammation and fibrosis.

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Background: Plate-related complications are major long-term complications in mandible reconstruction. There are controversies regarding the use of a reconstruction plate versus miniplates and a bone flap versus a soft tissue flap with a bridging plate. Direct comparisons of a fibula flap and an anterolateral thigh flap, the applicability between a reconstruction plate and miniplate, and the correlation between plate-related complications and quality of life remain unclarified.

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  • Endoscopy-assisted total mastectomy has been explored as a surgical option for breast cancer, with a study analyzing 436 procedures from 2009 to 2018, focusing on clinical outcomes and patient satisfaction.
  • Approximately 81.4% of the surgeries were nipple-sparing, with a low positive surgical margin rate of 2.1%, and significant patient satisfaction reported at 94.4%, especially among those receiving nipple-preserving reconstructions.
  • The study concluded that this technique is effective and safe for early breast cancer treatment, demonstrating positive long-term oncologic results and high aesthetic satisfaction among patients.
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Background: Maxillary defects after oncologic resection can lead to not only cosmetic deformity but also functional problem. Reconstruction of maxillary defects remains the most challenging endeavor for plastic surgeons. An algorithm to guide plastic surgeons in selecting either the anterolateral thigh flap or the fibula flap for oncologic maxillary reconstruction has not been well established.

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Purpose: It is not uncommon to see the synchronous presentation of esophageal squamous carcinoma (ESCC) and head and neck cancer (HNC), and most patients were treated with staged interventions. This study retrospectively reported the outcomes of patients with synchronous ESCC and HNC treated with one-stage concurrent surgical resection and reconstruction.

Methods: We identified 17 consecutive patients with synchronous ESCC and HNC undergoing primary concurrent surgical resections between 2011 and 2017 at our hospital.

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Introduction: The number of perforators required for safe perfusion remains under debate. This study aimed to determine whether a single- or multiple-perforator-based anterolateral thigh flap yields better flap outcomes in head and neck reconstruction.

Patients And Methods: Between August 2012 and July 2016, 180 men and 4 women with a mean age of 52.

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Aim: Infrapopliteal replantation is indicated in selected patients. When the patient is hemodynamically unstable or the amputation site is severely contaminated, temporary ectopic implantation of the amputated limb is an option. To the best of our knowledge, this is the first case report using the distal runoff vessel of the anterolateral thigh flap for temporary ectopic implantation of an amputated leg followed by replantation with the prefabricated anterolateral thigh flap.

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Background: Reconstruction for total laryngopharyngoesophagectomy is accomplished mainly by gastrointestinal transposition but can be complicated by anastomotic tension or associated neck-skin defect. Here, we present the results of total esophageal reconstruction by gastrointestinal transposition alone or with additional free tissue transfer and propose an algorithm accordingly.

Methods: We reviewed patients who had oncologic total laryngopharyngoesophagectomy between January 2012 and January 2016.

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Background: Although clinical assessment remains the gold standard for monitoring the circulation of free flaps, several adjunct techniques promote timely salvage by detecting circulation compromise early. The objective of this systematic review was to evaluate the efficacy of an implantable Doppler probe for postoperatively monitoring free flaps.

Materials And Methods: English-language articles evaluating the efficacy of implantable Doppler probes compared with clinical assessment for postoperatively monitoring free flaps were analyzed.

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Background: The titanium mesh or bone graft is usually used for orbital support after a globe-sparing total maxillectomy. However, its use can invite complications, such as infection, exposure, and absorption, especially for patients who require adjuvant radiotherapy. Here, the authors present a patient who received total maxillary reconstruction with an osteocutaneous fibular flap.

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The estimated prevalence of diabetes is 9.78% in Taiwan. The lifetime risk for patients with diabetes to have foot ulcers might be as high as 25%.

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