Publications by authors named "Tyrel Jones"

Psychiatric disorders are 1.5 to 2 times more prevalent in persons with inflammatory bowel disease (IBD) than in the general population, with pooled prevalence estimates of 21% for clinical anxiety and 15% for depression. Rates are even higher when considering mental health symptoms, as nearly one-third of persons with IBD experience elevated anxiety symptoms and one-quarter experience depression symptoms.

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Sex (the physical and physiologic effects resulting from having specific combinations of sex chromosomes) and gender (sex-associated behaviours, expectations, identities, and roles) significantly affect the course of inflammatory bowel disease (IBD) and the experience of living with IBD. Sex-influenced physiologic states, like puberty, the menstrual cycle, pregnancy, and andropause/menopause may also impact and be impacted by IBD. While neither Crohn's disease nor ulcerative colitis is commonly considered sex-determined illnesses, the relative incidence of Crohn's disease and ulcerative colitis between males and females varies over the life cycle.

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Article Synopsis
  • * In 2023, the estimated indirect costs of IBD in Canada are around $1.51 billion, primarily due to unemployment, absenteeism, and caregiving, with unemployment alone accounting for $1.14 billion.
  • * Overall, the combined costs associated with IBD in Canada are projected to exceed $2 billion CAD in 2023, reflecting a substantial increase from 2018 estimates due to rising prevalence and inflation.
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Article Synopsis
  • - The COVID-19 pandemic significantly affected individuals with inflammatory bowel disease (IBD), initially causing uncertainty about the virus's impact, especially for those on immunosuppressive medications.
  • - As research advanced, Crohn's and Colitis Canada created a task force to develop clinical guidelines, revealing that the risk of contracting COVID-19 for IBD patients is similar to the general public, although those actively flaring or on high doses of prednisone are more vulnerable to severe outcomes.
  • - Vaccination with a three-dose mRNA regimen shows strong antibody responses in IBD patients; however, breakthrough infections still occur, reinforcing the need for booster shots, while ongoing studies are required to understand long-term effects.
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Healthcare utilization among people living with inflammatory bowel disease (IBD) in Canada has shifted from inpatient management to outpatient management; fewer people with IBD are admitted to hospitals or undergo surgery, but outpatient visits have become more frequent. Although the frequency of emergency department (ED) visits among adults and seniors with IBD decreased, the frequency of ED visits among children with IBD increased. Additionally, there is variation in the utilization of IBD health services within and between provinces and across ethnocultural and sociodemographic groups.

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