Cytochrome P450 genes expression in human prostate cancer.

CYP-dependent metabolites play a critical role in regulating the cell cycle, as well as the proliferative, invasive, and migratory activity of cancer cells. We conducted a study to analyze the relative gene expression of various () in 41 pairs of prostate samples (tumor and conventional normal tissues) using qPCR. Our analysis determined significant individual variability in the expression levels of all studied both in the tumor and in conventionally normal groups.

Anaerobic Degradation of the Invasive Weed L. () and Copper Immobilization by a Community of Sulfate-Reducing and Methane-Producing Bacteria.

The weed L. poses a global threat to the environment as it spreads uncontrollably on roadsides, in forests, fields, meadows, and farmland. Goldenrod emits toxic substances that suppress other plants on the site, displacing wild ones.

Mast cells as a tumor microenvironment factor associated with the aggressiveness of prostate cancer.

We aimed to investigate the relationship between the degree of mast cells' (MCs) infiltration and clinicopathological features of prostate cancer (PCa) malignancy and to find out the possible mechanisms of the involvement of these cells in the formation of the aggressive course of the PCa development. The study was conducted on the clinical material of 60 patients with PCa of stages II-III. MCs in the PCa tissue were determined by a histochemical method using toluidine blue.

ILEOSIGMOID POUCH AS A URINARY DIVERSION APPROACH FOLLOWING RADICAL CYSTECTOMY IN PATIENTS WITH MUSCLE-INVASIVE BLADDER CANCER.

Goal - to determine efficacy of the Ileosigmo-pouch (ISP) as a method of transrectal urinary diversion in invasive bladder cancer (BC) treatment. Retrospective analysis of clinical data of patients that undergone radical cystectomy (RC), followed by ISP method of urinary diversion. Study compared two groups of patients: the first group of 22 (23.

The histological and electron microscopic study of the parotid salivary gland in dehydrated rats of different ages.

Objective: Introduction: Water-salt metabolism disorders is one of the main factor of salivary gland pathology development. The aim: To study the morphological structure of the parotid salivary gland of young, mature and old rats at micro- and ultrastructural levels under water deprivation.

Patients And Methods: Materials and methods: The experiment was carried out on thirty six laboratory male rats of different ages (young, mature and old).

Anatomical and morphological aspects of papillae, epithelium, muscles, and glands of rats' tongue: Light, scanning, and transmission electron microscopic study.

Purpose: The purpose of this paper is to describe the research results of the morphological structure of white laboratory rats' tongue at the macro-, micro-, and ultrastructural levels by scanning, light, and transmission electron microscopy.

Results: Our results show that the tongue of these rats has a number of unique morphological features that are different from the tongue of other rodents consequently to allow identifying their species-specific features.

Conclusions: Our findings have shown the features of the tongue structure of white laboratory rats at micro-, macro-, and ultrascopic levels.

The microscopic and ultramicroscopic changes in the skeletal muscles, caused by heavy metal salts.

Purpose: The article is devoted to study the structural changes in the skeletal muscles caused by heavy metal salts.

Materials And Methods: The study was conducted on 72 mature male rats. The experimental groups were given to drink water with combinations of heavy metal salts for one, two and three months.