[In vitro uranyle affinity of per (3,6-anhydro-2-O-carboxyméthyle)-alpha-cyclodextrin and conditions required for in vivo application].

Per (3.6-anhydro-2-O-carboxymethyle)- alpha-cyclodextrin ([1]) is a polydentate analog of EDTA, a well-known cation chelating reagent. [1] exhibits strong affinities in vitro for lanthanids, cobalt and also for uranyl cations.

[Methods to measure the cutaneous transfer of radionuclides across the intact or lesioned epidermis, application to radiotoxicology].

Although skin contamination by radionuclides is the most common cause of nuclear workers accidents, few studies dealing with the penetration of radioactive contamination through the skin are available. This work is a review of experimental methods that allow to assess transfer of radionuclides through the skin in occupational conditions, with or without skin trauma. The first section describes the different methods applied for skin transfer assessment of chemicals used in pharmacology.

[Efficiency of etidronic acid in the case of cutaneous radiocontamination by actinid elements: in vitro evaluation].

Ethane 1 hydroxy 1.1. biphosphonate (EHBP) is a medicine named Didronel, which inhibits bone resorption in the case of Paget's disease.

Contamination and decontamination of rat and human skin with plutonium and uranium, studied with a Franz's chamber.

Purpose: Our work offers a new method of assessing human skin radiocontamination and of appraising its treatment. This in vitro technique stems from methods used in skin pharmacology.

Materials And Methods: Franz's diffusion chambers, which help maintain the physiological condition of a skin biopsy, are used to study how 233U and 239Pu, added to a 0.

[Thorium a radioactive element in current use: physical-chemical properties and biological processing].

The radioactive properties and physicochemistry of thorium were studied and correlations drawn between thorium and element sof the titanium group, lanthanides and plutonium. It appears that the behavior of Th4+ and Pu4+ are similar, particularly their distribution pattern on bone surfaces. Chelating agents are reviewed and the structure of metal chelates indicated.