Neutrophils are a part of the innate immune system and produce reactive oxygen species (ROS) to extinguish pathogens. The major source of ROS in neutrophils is NADPH oxidase, which is fueled by NADPH generated via the pentose phosphate pathway; however, it is unclear how other accessory glucose metabolism pathways and mitochondrial activity influence the respiratory burst. We examined the temporal dynamics of the respiratory burst and delineated how metabolism changes over time after neutrophil activation.
View Article and Find Full Text PDFJ Strength Cond Res
November 2022
Jobe, TK, Shaffer, HN, Doci, CL, and Gries, KJ. Sex differences in performance and depth of field in the United States Olympic trials. J Strength Cond Res 36(11): 3122-3129, 2022-Recently, there has been an increased discussion on the role of sex as a variable in human performance.
View Article and Find Full Text PDFA significant amount of attention has been brought to the endocrine-like function of skeletal muscle on various tissues, particularly with bone. Several lines of investigation indicate that the physiology of both bone and muscle systems may be regulated by a given stimulus, such as exercise, aging, and inactivity. Moreover, emerging evidence indicates that bone is heavily influenced by soluble factors derived from skeletal muscle (i.
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