Publications by authors named "Tyler J Uppstrom"

Background: To improve outcomes following anterior cruciate ligament (ACL) reconstruction, bridge-enhanced ACL restoration (BEAR) was introduced. Bridge-enhanced ACL restoration uses a collagen-based implant saturated with infused autologous blood to bridge the torn proximal and distal ACL fibers.

Purpose: We sought to analyze the short-term complications, clinical outcomes, and patient-reported outcome measures (PROMs) in patients undergoing BEAR outside of the initial clinical trials.

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Article Synopsis
  • The study explored how the ultrastructural anatomy of the anterior cruciate ligament (ACL) tibial enthesis develops and matures in young children, aiming to show that it resembles adult anatomy by early postnatal stages.
  • Five fresh-frozen human pediatric knee samples (ages 1-36 months) were analyzed using scanning electron microscopy and histological techniques to observe changes in the enthesis structure over time.
  • Findings indicated that by 19 months, the ACL enthesis transitions to a more adult-like structure with notable changes in collagen fiber arrangements and complex remodeling correlating with increased mechanical loading from weightbearing.
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  • - Patients with recurrent patellofemoral instability may face issues with previous surgeries due to scar tissue and weakened bone structures, increasing the risk of complications like fractures.
  • - A new technique for revision stabilization merges methods from medial patellofemoral ligament (MPFL) reconstruction and medial quadriceps tendon-femoral ligament, using a single suture anchor for better fixation.
  • - This approach aims to improve lateral stability of the patella while reducing fracture risks by utilizing a smaller suture anchor, which is advantageous in cases with limited bone material.
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Injuries in pediatric and adolescent athletes continue to rise in the United States, with increases in year-round sports participation, earlier sport specialization, and inadequate access to neuromuscular training programs. In this setting, the use of magnetic resonance imaging (MRI) provides a critical diagnostic tool. This review article describes the utility of MRI in diagnosing common pediatric and adolescent sports injuries and presents imaging findings associated with these pathologies.

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Background: Medial patellar facet lesions have been well-described in the setting of patellar instability. However, relatively little is known about risk factors for atraumatic medial patellar facet lesions.

Purpose/hypothesis: To identify clinical and radiographic risk factors for medial patellar facet lesions in patients without a history of trauma or patellar instability.

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  • The study investigates the outcomes of ACL reconstruction (ACLR) using quadriceps tendon autograft (QTA) in skeletally immature athletes, addressing the increasing ACL injury rates in this population.
  • Previous methods, like hamstring tendon autograft (HTA), showed high failure rates in young athletes, while QTA demonstrated promising results in initial studies.
  • Following a minimum of 2 years of monitoring, the study evaluated clinical results and patient-reported outcomes in 83 adolescents, highlighting the success of different surgical techniques used based on skeletal age.
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  • Hip abductor deficiency is a common issue leading to lateral hip pain, especially in middle-aged individuals, and understanding potential spinal problems may help in treatment.
  • A study reviewed 131 cases of hip abductor tendon repairs from 2010 to 2021, classifying patients based on lumbar spine pathology related to nerve issues.
  • Findings revealed that over 40% of isolated repair patients and over 50% of those getting both repairs had evidence of lumbar spine pathology, suggesting that screening for spinal issues is essential for effective treatment.
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  • Tibial tubercle osteotomy (TTO) is a common surgery for issues related to patellofemoral instability and pain, with TTO-D (with distalization) being particularly indicated for specific patient conditions.* -
  • This study compared complication rates between TTO-D and TTO-ND (without distalization) in skeletally mature patients, finding similar complication rates of 5% for TTO-D and 7% for TTO-ND, with arthrofibrosis being the most frequent complication.* -
  • Factors affecting complications included the presence of concomitant intra-articular procedures for TTO-D patients and extended tourniquet time for TTO-ND patients, but overall, patient
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Background: Distalization tibial tubercle osteotomy (TTO) is an effective treatment for improving patellar height in patients with patella alta associated with patellofemoral instability and cartilage lesions. The addition of a patellar tendon tenodesis has been suggested; nonetheless, concerns exist regarding possible increased patellofemoral cartilage stresses.

Purpose: To evaluate pre- and postoperative patellar tendon length and alignment parameters on magnetic resonance imaging (MRI), as well as patient-reported outcome measures (PROMs) after distalization TTO without patellar tendon tenodesis.

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Background: Previous biomechanical studies evaluating medial meniscus posterior root tears (MMPRTs) are limited to low loads applied at specified loading angles, which cannot capture the effects of MMPRTs during the multidirectional forces and moments placed across the knee during physiological activities.

Purpose: To quantify the effects of MMPRTs on knee joint contact mechanics during simulated gait.

Study Design: Controlled laboratory study.

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Background: While increased posterior tibial slope (PTS) is an important risk factor for failure after anterior cruciate ligament (ACL) reconstruction, controversy exists regarding indications and outcomes of proximal tibia anterior closing-wedge osteotomy (ACWO) with concomitant ACL reconstruction in patients with ACL tears.

Purpose: To assess clinical outcomes after combined ACL reconstruction and proximal tibia ACWO.

Study Design: Systematic review; Level of evidence, 4.

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Purpose: Although most patellar dislocations are associated with medial patellofemoral ligament (MPFL) injury, many patients also sustain concomitant patellar osteochondral fractures following a patellar dislocation. Few prior studies have described or evaluated risk factors for patellar osteochondral fractures in pediatric patients. The purpose of the present study was to describe the incidenceand location of patellar osteochondral fractures following acute patellar dislocation in pediatric patients.

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  • The study aimed to compare how precisely different computer-assisted technologies perform bony resections during total knee arthroplasty (TKA).
  • Researchers reviewed 240 patients who had TKA: 120 with a handheld navigation system and 120 with a robotic system, analyzing postoperative alignment precision from their surgeries.
  • While there was a small, statistically significant difference in the precision of femoral resection between the two methods, both showed overall high precision; the study suggests considering other factors beyond technology when choosing a method for TKA.
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Purpose: The purpose of this study was to quantify differences in mechanical stability of a wedge-shaped distalization tibial tubercle osteotomy (TTO) with a standard technique, versus a modified technique with use of a proximal bone block and distally angled screw trajectory.

Methods: Ten fresh-frozen cadaver lower extremity specimens (five matched pairs) were utilized. Within each specimen pair, one specimen was randomly assigned to undergo a standard distalization osteotomy fixed with two bicortical 4.

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Background: A prior retrieval analysis found high rates of infection after conversion of PFA to TKA, but was limited by a small sample size. The purpose of this study is to perform a retrieval analysis with clinical correlation on an expanded group of patients to better understand conversion of PFA to TKA.

Method: A retrospective review of an implant retrieval registry identified 62 conversions of PFA to TKA between 2004-2021.

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Multidirectional instability of the shoulder can result from underlying atraumatic laxity, from repetitive microtrauma, or from a traumatic injury and often occurs in association with generalized ligamentous laxity or underlying connective tissue disorders. It is critical to differentiate multidirectional instability from unidirectional instability with or without generalized laxity to maximize treatment success. Although rehabilitation is still considered the primary treatment method for this condition, surgical treatment in the form of open inferior capsular shift or arthroscopic pancapsulolabral plication is indicated if conservative treatment fails.

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Introduction: There is a paucity of data on patient reported outcome measures (PROMs) associated with surgical treatment of osteochondritis dissecans (OCD). As a result, preoperative patient and family counseling regarding expected outcomes is difficult. The purpose of this study was to compare pre-to post-operative changes in PROMs amongst cohorts of patients with OCD that underwent one of three lesion-specific surgical treatments: 1) transarticular drilling for stable lesions, 2) drilling and fixation for unstable lesions 3) grafting for unsalvageable lesions.

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Objective: Patellofemoral cartilage restoration procedures, including osteochondral allograft, particulated juvenile cartilage, and matrix-induced autologous chondrocyte implantation, have been shown to be effective treatments for patellofemoral cartilage lesions. However, concerns exist regarding disruption of the patellar vascular supply and secondary stabilizers of the patellofemoral joint during medial parapatellar approaches, especially when combined with a lateral release. A lateral parapatellar approach affords the possibility of avoiding disruption of the medial blood supply to the patella, while also allowing laterally-based soft tissue stabilization procedures.

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Purpose: To define the minimal detectable change (MDC) for the international knee documentation committee (IKDC) and Kujala scores one and two years after patellofemoral joint arthroplasty (PFA).

Methods: A distribution-based method (one-half the standard deviation of the mean difference between postoperative and preoperative outcome scores) was applied to establish MDC thresholds among 225 patients undergoing primary PFA at a single high-volume musculoskeletal-care center. Stability of change in MDC achievement was explored by quantifying the proportion of achievement at one- and two-year postoperative timepoints.

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Case: A 57-year-old man presented with a left knee dislocation after a motor vehicle collision. Clinical and imaging evaluation demonstrated disruption of the anterior cruciate ligament (ACL), posterior cruciate ligament (PCL), anterolateral ligament (ALL), and posterolateral corner (PLC). The patient underwent acute, single-stage arthroscopic primary ACL and PCL repair, with arcuate fracture fixation using a novel technique.

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Background: Open repair for gluteus medius and minimus tears is a common surgical treatment for patients with lateral hip pain associated with abductor tears; however, clinically meaningful outcomes have not been described after open surgical treatment.

Purpose: To define the minimal clinically important difference (MCID) in patient-reported outcome measures (PROMs) in patients undergoing open gluteus medius or minimus repair, and to identify preoperative patient characteristics predictive of achieving MCID postoperatively.

Study Design: Case series; Level of evidence, 4.

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Core muscle injuries are common injuries in athletes involved in high speed side-to-side acceleration movements. The term core muscle injury encapsulates several different injuries that occur in the pelvic region that have similar presentations. Along with a good history and physical examination, magnetic resonance imaging (MRI) can be a helpful tool in the diagnostic process.

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Background: Juvenile osteochondritis dissecans (JOCD) lesions are rarely located in the trochlea and few studies have focused on the causes and outcomes of JOCD lesions in this part of the knee. The purpose of this study is to (1) evaluate the clinical characteristics and outcomes of patients who undergo surgery for JOCD in this unusual location as well as (2) assess the association between trochlear JOCD and participation in sporting activities that load the patellofemoral joint.

Methods: We conducted a retrospective cohort study of 34 trochlear JOCD lesions in 30 patients.

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Background: Artificial meniscal scaffolds are being developed to prevent development of osteoarthritis after meniscectomy. Previously, it was reported that 3-dimensional (3D) anatomic scaffolds loaded with connective tissue growth factor (CTGF) and transforming growth factor β3 (TGF-β3) achieved meniscal regeneration in an ovine model. This was a relatively short-term study (3 months postoperative), and outcome analyses did not include magnetic resonance imaging (MRI).

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Mechanical stress has an important effect on tendon-to-bone healing. The purpose of the present study was to compare tendon-to-bone healing in animals exposed to either tendon unloading (botulinum toxin injection) or excessive loading (treadmill running) in a murine rotator cuff repair model. Forty-eight C57BL/6 mice underwent unilateral supraspinatus tendon detachment and repair.

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