Publications by authors named "Tyler J Hellmig"

Article Synopsis
  • Maackia amurensis lectins, specifically M. amurensis seed lectin (MASL), bind to sialic acid residues on proteins, showing potential to reduce inflammation in arthritic cells and inhibit tumor growth and movement.
  • The study characterized MASL into two groups based on its ability to form dimers, with MASL having unique isoforms and glycosylation sites that significantly impact its function and interaction with the podoplanin (PDPN) receptor.
  • Results indicate that MASL exhibits strong binding to PDPN and can effectively inhibit the growth and motility of oral squamous cell carcinoma (OSCC) cells, highlighting its potential use as an antic
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