Publications by authors named "Tyler Biebighauser"
Article Synopsis
- Ewing sarcoma is the second most common bone cancer in kids, and those diagnosed with metastatic disease have a poor outlook due to the presence of the EWS/Fli1 fusion gene that drives tumor growth.
- Research shows that the Wnt/β-Catenin signaling pathway in Ewing sarcoma cells is activated differently depending on the tumor environment, especially in relation to hypoxia and EWS/Fli1 activity.
- The study identifies CDH11 as a crucial factor in how Wnt/β-Catenin signaling varies among tumor cells, suggesting it could be a potential target for treatment to improve outcomes in Ewing sarcoma patients.
