Descriptions of Scientific Evidence and Uncertainty of Unproven COVID-19 Therapies in US News: Content Analysis Study.

Background: Politicization and misinformation or disinformation of unproven COVID-19 therapies have resulted in communication challenges in presenting science to the public, especially in times of heightened public trepidation and uncertainty.

Objective: This study aims to examine how scientific evidence and uncertainty were portrayed in US news on 3 unproven COVID-19 therapeutics, prior to the development of proven therapeutics and vaccines.

Methods: We conducted a media analysis of unproven COVID-19 therapeutics in early 2020.

Longitudinal Improvement in Public Speaking Skills Through Participation in a Resident Public Speaking Curriculum.

Objective: To promote public speaking skills, a pediatrics residency program developed a longitudinal public speaking curriculum grounded in deliberate practice and reflective practice.

Methods: Residents delivered annual presentations and received formal feedback. Audience evaluation forms from 2005 to 2017 were included for analysis.

Glucagon fill rates and cost among children and adolescents with type 1 diabetes in the United States, 2011-2021.

Aims: To characterize glucagon fill rates and costs among youth with type 1 diabetes mellitus (T1DM).

Methods: Claims-based analysis of commercially-insured youth with T1DM included in OptumLabs® Data Warehouse between 2011 and 2021. Glucagon fill rates and costs were calculated overall and by formulation (injectable, intranasal, autoinjector, and pre-filled syringe).

Evolution of Clinical Complexity, Treatment Burden, Health Care Use, and Diabetes-Related Outcomes Among Commercial and Medicare Advantage Plan Beneficiaries With Diabetes in the U.S., 2006-2018.

Objective: To characterize trends in clinical complexity, treatment burden, health care use, and diabetes-related outcomes among adults with diabetes.

Research Design And Methods: We used a nationwide claims database to identify enrollees in commercial and Medicare Advantage plans who met claims criteria for diabetes between 1 January 2006 and 31 March 2019 and to quantify annual trends in clinical complexity (e.g.

Inpatient pediatric chaplain service utilization among children with chronic, non-cancer diseases.

Despite the broad importance of pediatric spiritual care, most research focuses on oncologic and palliative care contexts. We aim to describe the utilization of pediatric chaplain services by children hospitalized for non-cancer chronic illnesses and to identify factors that predict utilization of chaplain services. Among 629 patients with 915 admissions, we found chaplain services were utilized in 5.

Drug labeling changes and pediatric hematology/oncology prescribing: Measuring the impact of U.S. legislation.

Background/aims: The Pediatric Research Equity Act and Best Pharmaceuticals for Children Act are intended to promote the conduct of clinical trials that generate pediatric-specific evidence about drug safety and efficacy. This study assesses the quality of evidence generated through Pediatric Research Equity Act-mandated and Best Pharmaceuticals for Children Act-incentivized clinical trials of hematology/oncology drugs and characterizes subsequent changes in pediatric drug utilization rates.

Methods: Trial characteristics (blinding, randomization, and comparator group) were determined for clinical trials that supported pediatric label changes.

Development of a Taxonomy for Medication-Related Patient Safety Events Related to Health Information Technology in Pediatrics.

Background: Although electronic health records (EHRs) are designed to improve patient safety, they have been associated with serious patient harm. An agreed-upon and standard taxonomy for classifying health information technology (HIT) related patient safety events does not exist.

Objectives: We aimed to develop and evaluate a taxonomy for medication-related patient safety events associated with HIT and validate it using a set of events involving pediatric patients.

Frequency and Specificity of Pediatric Health Policy Discussions in Political Campaigns.

This cross-sectional study analyzed a database of Congressional candidate campaign websites to assess the frequency and specificity of pediatric health policy discussions in political campaigns.