Tumefactive (giant) perivascular spaces of the brain are a rare benign lesion that may occasionally result in localized neurological symptoms and typically do not change in appearance on subsequent imaging studies. Here we report a case of a 65-year-old woman with newly diagnosed lung cancer that underwent routine staging MRI of the brain. She was found to have a cystic temporal lobe lesion with imaging features consistent with a tumefactive perivascular space.
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