Publications by authors named "Tycova V"

Background: Gastrointestinal stromal tumors (GISTs) may arise in any part of the gastrointestinal tract; extra-gastrointestinal locations are extremely rare. Only a few cases of extragastrointestinal stromal tumor arising from the pancreas were reported. None of the reports described a long-term follow-up of the patients.

View Article and Find Full Text PDF

Cryptogenic multifocal ulcerous stenosing enteritis (CMUSE) is a rare condition characterised by chronic or relapsing moderate ileous episodes resulting from multiple small intestinal strictures, multiple shallow ulcers of the small bowel and favourable therapeutical effect of glucocorticosteroids. The aim of this paper was to evaluate three cases of CMUSE diagnosed within 10 years at a tertiary gastroenterology centre. Three females (35, 50, 60 years) were presented with colicky pain, repeated moderate ileous episodes and weight loss.

View Article and Find Full Text PDF

Introduction: Precise evaluation of lymph nodes in the surgical specimen is crucial for the staging and subsequent decision about the adjuvant therapy in colorectal cancer. Prognosis of the patients can be assessed only in cases when at least 12 lymph nodes in the surgical specimen are examined.

Aim Of The Work: To evaluate the radicalism of resections for colorectal carcinoma after introducing laparoscopic approach.

View Article and Find Full Text PDF

The major postoperative complication after open and laparoscopic distal pancreatectomy is pancreatic fistula. Different operative techniques have been tested to minimize this unpleasant complication. We evaluated a new technique for pancreatic stump reinforcement with synthetic glue after laparoscopic distal pancreatectomy.

View Article and Find Full Text PDF

Background/aims: Metastatic renal cell carcinoma (RCC) is a malignant tumor characterized by great variation in the clinical course and unusual sites of metastases. Metastases to the pancreas are, in general, rare.

Methodology: A retrospective chart review of patients treated a single institution.

View Article and Find Full Text PDF

Background/aims: A retrospective evaluation was oerformed to determine whether the intensity of p53, p21 or p16 expression predicts response to preoperative chemoradiotherapy in locally advanced gastric carcinoma.

Methodology: Thirty-six patients (cT2-4 or N+) were studied. Preoperative treatment consisted of 30-45Gy of radiation with continuous 5-fluorouracil and weekly cisplatin.

View Article and Find Full Text PDF

Background/aims: Pancreatic cystic neoplasms represent a heterogeneous group of tumors with varied malignant potential. The aim of this prospective study was to evaluate EUS, EUS-FNA and cyst fluid analysis in distinguishing serous cystadenomas (SCA) and mucinous cystic neoplasms (MCN).

Methodology: Twelve patients with SCA (4 men, 8 women, mean age 58), 16 with MCN (3 men, 13 women, mean age 53) and 10 pancreatic non-tumorous cysts as controls (1 man, 9 women, mean age 43) were investigated by EUS-FNA from January 2003 to February 2006.

View Article and Find Full Text PDF

The aim of this project was to develop a methodology to introduce wireless video capsule endoscopy in preclinical research. Five mature female pigs (Sus scrofa domestica) were selected for the study. Capsule endoscopes (the EndoCapsule system; Olympus) were introduced into the duodenum endoscopically in each of the animals.

View Article and Find Full Text PDF

Introduction: Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. Authors present a 67-year-old woman treated for iron deficiency anemia for the past 5 years. Suddenly, her disease was presented with painless severe gastrointestinal bleeding (fresh melena).

View Article and Find Full Text PDF

Unlabelled: The aim of the study was to evaluate the influence of sliding hiatal hernia over the Barrett's oesophagus, including symptoms rate and complications.

Methods: A total of 520 (4.6%) cases of Barrett's oesophagus were found out of 18.

View Article and Find Full Text PDF
Article Synopsis
  • - The study aimed to evaluate whether the level of epidermal growth factor receptor (EGFR) expression can predict the tumor response in patients with locally advanced gastric cancer who received preoperative chemoradiotherapy.
  • - Out of 36 patients, 17 showed a positive tumor response to treatment, with 22% of them having positive EGFR expression, which was linked to a poorer response in the overall analysis (p = 0.015).
  • - The findings suggest that high EGFR expression may indicate a lower likelihood of tumor response to preoperative chemoradiotherapy, making it a potential molecular marker for predicting treatment outcomes in these patients.
View Article and Find Full Text PDF

Systemic AL-amyloidosis is a disorder brought about by the over-production and deposition of fragments of light immunoglobulin chains in tissues, the consequence of which is their functional impairment. The most often affected are the kidneys, the heart, the gastro-intestinal tract and the nervous system. We describe the case of a 57-year-old patient in whom a rare disorder of the striated muscle (am yloid myopathy) was present, as the first clinical indication of systemic AL-amyloidosis.

View Article and Find Full Text PDF

Aim: To evaluate the feasibility of liver blood outflow (LBOF) occlusion and its impact on the effectiveness of radiofrequency ablation (RFA).

Methods: The experiment was performed on 10 pigs. The animals were divided into groups A and B according to RFA protocol.

View Article and Find Full Text PDF

Cardiomyopathy (CMP) was found in 26 children with cystic fibrosis (CF), 24 of them died, the majority of them during the first 3 years of life. Only 4 of them were older than 10 years. 2 children are living.

View Article and Find Full Text PDF