Publications by authors named "Twinkle Pawar"
Article Synopsis
- * A case of a 54-year-old man with type 2 diabetes showed worsening pain in his calf, where tests confirmed muscle injury and inflammation as the cause of his symptoms.
- * Treatment included hemodialysis, medications for pain and blood sugar control, and lifestyle changes, highlighting the need for early diagnosis and management of DMI to prevent complications.
Article Synopsis
- Carpenter syndrome is a rare autosomal recessive disorder caused by RAB23 mutations, marked by features like craniofacial anomalies, heart disease, brachydactyly, and obesity.
- With an incidence of about one in a million births, diagnosing this syndrome can be difficult due to its variety of symptoms.
- This case report connects Carpenter syndrome to chronic kidney disease (CKD), highlighting the need for more research on the genetic links and clinical management of these conditions.
Article Synopsis
- - The case report highlights a 48-year-old woman with chronic kidney disease who developed pure red cell aplasia (PRCA) due to anti-erythropoietin (EPO) antibodies after receiving EPO injections for anemia.
- - Following a severe drop in her hemoglobin levels, she was treated with desidustat, a new oral medication that improved her hemoglobin significantly while being less likely to induce an immune response.
- - This case emphasizes the importance of quick diagnosis and the potential of desidustat as a safer alternative for treating anemia in patients, showcasing advancements in treatment within the context of the first reported case in India.
Article Synopsis
- Renal aspergillosis is a rare but serious complication following kidney transplants, highlighted by the case of a 45-year-old man who had a transplant from his mother.
- After initially recovering, the patient faced kidney dysfunction and signs of systemic infection due to active antibody-mediated rejection, leading to a diagnosis of renal aspergillosis.
- Despite aggressive treatment efforts, the patient's condition worsened to renal graft cortical necrosis, resulting in the need for nephrectomy, emphasizing the importance of early diagnosis and intervention in transplant patients.
Article Synopsis
- Membranous nephropathy (MN) is a major cause of nephrotic syndrome in non-diabetic adults and can be primary (due to autoantibodies) or secondary to other illnesses.
- A rare type, NELL-1-associated MN, poses diagnostic challenges and can lead to complications like renal vein thrombosis (RVT), which is not often documented.
- A case study of a 43-year-old male with NELL-1-positive MN complicated by RVT shows successful treatment with thrombolysis and emphasizes the need for more research on anti-NELL-1 antibodies and personalized anticoagulation strategies for better management.
Tissue necrosis and ischemia are hallmarks of acute necrotizing pancreatitis, which frequently results in fatal infections. In this case, we describe a man in his 40s who had diffuse pain in the abdomen, intractable vomiting, diarrhoea, and intermittent fever. His abdominal computed tomography revealed acute pancreatitis with peripancreatic fluid collection, gastric perforation, and fistula formation between the greater curvature of the stomach and transverse colon.
View Article and Find Full Text PDFDiffuse alveolar hemorrhage (DAH) is bleeding into the alveolar spaces of the lung. DAH is often associated with systemic autoimmune diseases, coagulation disorders, drugs, inhaled toxins, or transplantation. This study describes a rare case of acenocoumarol-induced DAH, a pulmonary disorder, which has not been reported before.
View Article and Find Full Text PDFWe present a case of a 50-year-old female who came to us with chief complaints of breathlessness, general weakness, and cough. She tested positive for coronavirus disease 2019 (COVID-19) on testing with Reverse Transcription Polymerase Chain Reaction (RT-PCR). She had high resolution computed tomography (HRCT) thorax score of 22/25.
View Article and Find Full Text PDFArticle Synopsis
- Endothelial cell injury and the formation of thrombi in blood vessels are key features of hemolytic uremic syndrome (HUS) and thrombotic thrombocytopenic purpura (TTP), both leading to acute kidney damage.
- In a specific case, a patient experienced acute kidney injury following a blood transfusion, which later resulted in neurological complications.
- Treatment for the patient was primarily supportive, but plasmapheresis and corticosteroids were administered and showed positive outcomes.
Sildenafil citrate is a specific phosphodiesterase type 5-enzyme blocker that can enhance the indirect impacts of nitric oxide on vascular smooth muscle and permeability via the guanosine monophosphate (c-GMP) route in the penis erectile tissue. Though the medication is well taken, particular side effects such as flushes, headache, indigestion, and retinal abnormalities have indeed been reported. Liver toxicity caused by sildenafil use is thought to be quite infrequent.
View Article and Find Full Text PDFBackground There is a continual rise in the prevalence of non-cancerous conditions such as chronic kidney disease (CKD) owing to an enormous load of diabetes, hypertension, and vascular diseases. A positive attitude and healthy lifestyle for CKD prevention can only be followed when the masses are well aware and educated about the disease. This study aimed to compare, correlate, and evaluate the distribution of knowledge, attitudes, and perceptions among relatives or caretakers of patients with kidney disease or at risk of the disease.
View Article and Find Full Text PDFArtery of Percheron (AOP) is a unique anatomical variant of blood supply to the paramedian thalamus and also to the rostral part of the midbrain. It arises from the P1 part of the posterior cerebral artery. Obstruction of this artery accounts for the infarction of the bilateral thalamus with or without the involvement of the midbrain.
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