Publications by authors named "Tuyen T Nguyen"
Article Synopsis
- Bacterial vaginosis (BV) is a common vaginal infection in pregnant women, particularly impacting health outcomes during pregnancy, yet screening isn't routine in Vietnam.
- A study involving 885 pregnant women in their third trimester found that 11.1% had BV, with a significant number also experiencing fungal infections and past miscarriage linked to higher rates of BV.
- The findings emphasize the need for increased awareness and routine testing for BV in pregnant women to improve health outcomes, particularly in relation to symptoms like fishy discharge.
We herein propose a fast and easy DNA and RNA co-extraction method for environmental microbial samples. It combines bead beating and phenol-chloroform phase separation followed by the separation and purification of DNA and RNA using the Qiagen AllPrep DNA/RNA mini kit. With a handling time of ~3 h, our method simultaneously extracted high-quality DNA (peak size >10-15 kb) and RNA (RNA integrity number >6) from lake bacterioplankton filtered samples.
View Article and Find Full Text PDFBackground: Aerobic vaginitis (AV) is a vaginal inflammation characterized by disruption of the lactobacillus microbiota and increased counts of different aerobic bacteria. AV may result in severe complications, especially during pregnancy, including preterm delivery, neonatal and maternal infections. This study aimed to determine the prevalence of AV in the third trimester of pregnancy, and the relationship between AV and pregnancy outcomes.
View Article and Find Full Text PDFBackground: Short meal-to-bed time (MTBT) has been reported to relate to gastroesophageal reflux disease (GERD), but evidence is lacking in pregnant women. We aimed to assess the characteristics of GERD and the association between MTBT and GERD during pregnancy.
Patients And Methods: A cross-sectional study was carried out on 400 pregnant women aged 18 years and older visiting the antenatal clinic of Gia-Dinh People's Hospital, Vietnam.
CD4⁺ T-lymphocyte destruction, microbial translocation, and systemic immune activation are the main mechanisms of the pathogenesis of human immunodeficiency virus type 1 (HIV) infection. To investigate the impact of HIV infection and antiretroviral therapy (ART) on the immune profile of and microbial translocation in HIV-infected children, 60 HIV vertically infected children (31 without ART: HIV(+) and 29 with ART: ART(+)) and 20 HIV-uninfected children (HIV(-)) aged 2-12 years were recruited in Vietnam, and their blood samples were immunologically and bacteriologically analyzed. Among the HIV(+) children, the total CD4⁺-cell and their subset (type 1 helper T-cell (Th1)/Th2/Th17) counts were inversely correlated with age (all p < 0.
View Article and Find Full Text PDFBackground: High-pressure homogenization disrupts cell structures, assisting carotenoid release from the matrix and subsequent micellarization. However, lycopene bioaccessibility of tomato puree upon high-pressure homogenization is limited by the formation of a process-induced barrier. In this context, cell wall-degrading enzymes were applied to hydrolyze the formed barrier and enhance lycopene bioaccessibility.
View Article and Find Full Text PDFArticle Synopsis
- RARγ2 is a key retinoic acid receptor involved in the development of the caudal region in vertebrates, functioning at all stages of axial elongation rather than just as a stop signal.
- It represses gene activity when not activated by retinoic acid (RA), helping maintain progenitor cell pools and controlling somite differentiation when RA is present.
- Manipulating RARγ2’s activity, either by using specific agonists or inverse agonists, shows that it plays a crucial role in regulating gene expression, impacting body axis growth and structure formation in embryos like those of Xenopus.