Effect of streptozotocin on reactive oxygen species and antioxidant enzyme secretion in rat submandibulary glands: a direct and an indirect relationship between enzyme activation and expression.

The salivary glands are important exocrine and endocrine organs, whose role in oral health is well recognized. Also these glands contribute to the maintenance of systemic health. During diabetes an impairment of salivary glands is reported.

Antiproliferative activity of Larrea divaricata Cav. on lymphoma cell line: participation of hydrogen peroxide in its action.

Larrea divaricata is a plant used in Argentina. The aim was to analyze the participation of H2O2 in the antiproliferative effect of L divaricata on BW5147 cells. Different studies were performed: proliferation, viability, nitrite production, apoptosis, oxygen reducing activity, NF-kappa B translocation, H2O2 production, H2O2 scavenging activity, and effect on exogenous superoxide dismutase.

Antioxidant activity of limonene on normal murine lymphocytes: relation to H2O2 modulation and cell proliferation.

Limonene is a monoterpene present in citrus fruit and is used as flavouring agents of foods. It was shown that monoterpenes possess antioxidant activity. Previously, it was demonstrated that limonene exerts anti-proliferative action on a lymphoma cell line without modifying normal lymphocyte viability.

Effect of caffeine on the secretion of peroxidase in rat submandibular gland: a study of its mechanism of action.

Objective: In this work, we analysed the mechanism of action of caffeine on peroxidase secretion in the female rat submandibular gland. The signaling molecules cAMP and nitric oxide were monitored as potential mediators.

Design: The salivary gland peroxidase secretion of female albino Wistar rats was assessed by a spectroscopic method.

Effect of Ilex extracts and isolated compounds on peroxidase secretion of rat submandibulary glands.

Free radicals are involved in diverse disorders such as tumoral, central nervous system alterations, immunological and inflammatory pathologies. Peroxidase is an oral enzyme involved in the defense of the oral cavity. Ilex species such as Ilex paraguariensis St.

Effect of Larrea divaricata Cav. extract and nordihydroguaiaretic acid upon peroxidase secretion in rat submandibulary glands.

Free radicals are involved in several diseases, including cancer, central nervous system alterations and inflammatory pathologies. Peroxidase is an oral enzyme implicated in the defence of oral cavity. It has been determined that flavonoids and lignans possess antioxidant and free radical scavenging either directly or indirectly, usually by means of increasing the secretion of free radicals scavenger enzymes.