[Osteoiliacography as diagnostic method of vena cava inferior circulation failure in liver cirrhosis].

Hypertension developing in the vena cava system under conditions of cirrhosis results in the formation of collateral blood outflow into vena cava superior (VCS) and inferior, at the same time the carrying capacity of vena cava inferior (VCI) might be limited due both to its fixation in the rigid diaphragm ring and to the fact that the hepatic segment of VCI is compressed by regenerated nodes. The increased volume of blood outflow via VCI with a simultaneous constriction of its hepatic segment results in the development of caval hypertention which even more complicates the transhepatic blood flow. Increased pressure in the VCI system with the formation of suprahepatic postsinusoidal block creates additional considerable barriers for blood outflow from the liver aggravating the failure of portal circulation, creating vicious circle that leads to decompensation of both regional visceral and common venous hemodynamics.

[Comparative analysis of treatment modes of acute ezophago-gastric bleedings in patients with portal hypertension].

40 years' experience of treatment of acute ezophago-gastric bleedings in patients with portal hypertension is analyzed. In dependence of the treatment trends, three periods of of time were assigned. The 1st period was characterized by surgical treatment nonmetering clinical features.

[Principles of the present-day conservative therapy of gastro-intestinal bleedings in portal hypertension].

The dynamics of conservative treatment of 1091 patients was analyzed for the period from 1964 through 2000. Best results were obtained when instead of traditional hemostatic therapy the patients were treated by combined methods aimed not only at obtaining hemostasis but also at elimination of disorders in the aggregate composition of blood, of microcirculatory disorders, that promoted restoration of the functional ability of the liver. With that end in view, fresh-frozen plasma, albumin, membranotropic, antioxidant, desaggregant and detoxicating therapy were used, with hematocrit lower than 30% hemocomponents were used.

[Aggregation state of blood and the significance of its impairments in bleedings of portal genesis].

Account of such indices of blood rheology as viscosity, erythrocyte aggregation coefficient, indices of lipid peroxidation and endogenous intoxication allowed the authors to fulfill therapeutic treatment of patients with hemorrhage of portal genesis more efficiently.

[Strategy of treatment for bleeding of portal genesis].

Based on a comparative analysis of results of the surgical treatment of bleedings from varicose veins of the liver and stomach, the authors recommend differential decision for the variants of surgical interventions at different periods from the moment of the appearance of bleeding and depending on the severity of impairments of the liver functions.

[The significance of disturbances of draining functions of the azygos vein in pathogenesis of varicose dilatation of the veins of the esophagus and stomach in portal hypertension (experimental-clinical investigation)].

Under analysis were the results of investigations on 30 corpses, 25 dogs and of examinations of 187 patients with portal hypertension. In the experiments the disturbances of blood flow in the portal and azygos veins and the veins of the gastroesophageal basin were modeled. It was found that changes of the veins of the esophago-gastric area in diffuse lesions of the liver were already present even if there were no definitely detectable signs of portal hypertension.