Publications by authors named "Turki M AlFayea"

Article Synopsis
  • This study focused on metastatic renal cell carcinoma (mRCC), examining the survival outcomes of first-line immuno-oncological (ICI) regimens compared to single-agent tyrosine kinase inhibitors (TKIs) in Saudi Arabian patients.
  • A total of 84 patients diagnosed with clear cell mRCC were analyzed, showing a median progression-free survival (PFS) of 9.7 months and an overall survival (OS) of 42.0 months, with no significant difference between treatment groups.
  • The results indicated that first-line single-agent ICI therapy demonstrated promising anti-tumor activity and survival outcomes similar to both ICI-based combinations and TKIs, with liver metastasis and lower performance status being significant
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Article Synopsis
  • Subependymal giant cell astrocytoma (SEGA) is a rare type of brain tumor associated with tuberous sclerosis (TSC), affecting around 25% of TSC cases.
  • A 14-year-old girl presented with headaches and an intraventricular mass near critical brain structures, leading to surgical removal, which alleviated her symptoms.
  • Although she exhibited SEGA without a diagnosis of TSC, she developed new lesions later and was treated with everolimus, resulting in a reduction of her tumors on imaging.
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Introduction Pancreatic adenocarcinoma and type 2 diabetes mellitus (T2DM) are inter-related. The outcomes of this association were the topic of interest of a lot of prior research in this field. The primary objective of this research is the identification of the survival rate and mortality difference between patients with pancreatic adenocarcinoma and T2DM and those without.

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Background: Bleomycin pulmonary toxicity (BPT) has been described in Hodgkin's lymphoma (HL) patients treated with bleomycin-containing chemotherapy regimens.

Methodology: We reviewed the records of 164 consecutive HL patients.

Results: BPT was observed in 24 of 164 patients (15%).

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Background: The prognostic role of thyroid transcription factor-1 (TTF-1) expression in lung cancer has been assessed but with inconsistent results. The present study aimed to evaluate the prognostic value of TTF1 expression in advanced non-squamous non-small cell lung cancer (NSCLC).

Materials And Methods: In this retrospective study, patients with stage IIIB-IV non-squamous NSCLC were enrolled.

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The treatment of elderly cancer patients is complicated by many factors. We sought to assess the uptake and tolerance of chemotherapy among patients 75 years and older diagnosed with small cell lung cancer (SCLC) in years 2004-2008 in Alberta, Canada, and assess their survival. All patients who met the above criteria and had an oncologist-consult were included.

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Background: Patients treated for Hodgkin's lymphoma (HL) have a higher risk of developing second lung cancer (SLC) compared with the general population. The aim of this meta-analysis was to quantify such risk and to analyze contributing risk factors in HL survivors.

Methods: According to predefined selection criteria, a literature search identified 21 studies that were included in the analysis.

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