Traumatic stress and post-traumatic growth in individuals who have had Covid-19: The mediating effect of resilience and moderating effect of psychological flexibility.

The Covid-19 pandemic has had a global impact and has negatively affected the mental health of individuals. It is known that depression, anxiety and traumatic stress levels are high in individuals who have experienced Covid-19. In light of this, an increase in Post-Traumatic Growth (PTB) levels is expected.

Psychometric properties and validation of the metacognitive self-assessment scale (MSAS) in a Turkish sample.

Objective: Metacognition, a multifaceted psychological construct, encompasses recognising and explaining one's cognitive processes and those of others. Notably, deficits in metacognitive abilities are linked with diminished social performance, reduced quality of life, and increased severity of Personality Disorders (PD). While there are other assessment tools available in Turkish for evaluating metacognition, none offer the same combination of speed, simplicity, flexibility, and multidimensionality for screening metacognitive abilities as the Metacognition Self-Assessment Scale (MSAS).

Effects of mindfulness on test anxiety: a meta-analysis.

Objective: This meta-analysis evaluated the effectiveness of mindfulness-based interventions (MBIs) on test anxiety across diverse age groups and intervention modalities.

Methods: Rigorous inclusion criteria were applied to select studies focusing on MBIs as the independent variable, with test anxiety as the outcome. A comprehensive search across multiple databases yielded 18 primary studies, contributing 20 comparisons.

Integrated care policy recommendations for complex multisystem long term conditions and long COVID.

The importance of integrated care for complex, multiple long term conditions was acknowledged before the COVID pandemic but remained a challenge. The pandemic and consequent development of Long COVID required rapid adaptation of health services to address the population's needs, requiring service redesigns including integrated care. This Delphi consensus study was conducted in the UK and found similar integrated care priorities for Long COVID and complex, multiple long term conditions, provided by 480 patients and health care providers, with an 80% consensus rate.

Synthesis of zeolite from industrial wastes: a review on characterization and heavy metal and dye removal.

Increasing world population, urbanization, and industrialization have led to an increase in demand in production and consumption, resulting in an increase in industrial solid wastes and pollutant levels in water. These two main consequences have become global problems. The high Si and Al content of solid wastes suggests that they can be used as raw materials for the synthesis of zeolites.

Tetracycline (TC) removal from wastewater with activated carbon (AC) obtained from waste grape marc: activated carbon characterization and adsorption mechanism.

In this study, activated carbons were obtained from grape marc for tetracycline removal from wastewater. Activated carbons were obtained by subjecting them to pyrolysis at 300, 500, and 700 °C, respectively, and the effect of pyrolysis temperature on activated carbons was investigated. The physicochemical and surface properties of the activated carbons were evaluated by SEM, FTIR, XRD, elemental analysis, N adsorption/desorption isothermal, thermal gravimetric (TG) and derivative thermogravimetric (DTG), and BET surface area analysis.

How can we further explore the link between self-criticism and self-compassion, and disordered eating? Commentary on Paranjothy and Wade's (2024).

Paranjothy and Wade's (2024, A meta-analysis of disordered eating and its association with self-criticism and self-compassion. International Journal of Eating Disorders. https://doi.

Accessing care for Long Covid from the perspectives of patients and healthcare practitioners: A qualitative study.

Background: Long Covid is an emerging long-term condition, with those affected raising concerns about lack of healthcare support.

Objective: We conducted a qualitative study to identify facilitators and barriers to healthcare access for people with Long Covid, aiming to enhance our understanding of the specific nature of these barriers and how patient experiences may vary.

Setting And Participants: In the context of the Symptoms, Trajectory, Inequalities and Management: Understanding Long-COVID to Address and Transform Existing Integrated Care Pathways (STIMULATE-ICP) Delphi study, a nationally distributed online survey was conducted.

Prevalence of mental health conditions and brain fog in people with long COVID: A systematic review and meta-analysis.

Objective: Long COVID can include impaired cognition ('brain fog'; a term encompassing multiple symptoms) and mental health conditions. We performed a systematic review and meta-analysis to estimate their prevalence and to explore relevant factors associated with the incidence of impaired cognition and mental health conditions.

Methods: Searches were conducted in Medline and PsycINFO to cover the start of the pandemic until August 2023.

RNGU-NET: a novel efficient approach in Segmenting Tuberculosis using chest X-Ray images.

Tuberculosis affects various tissues, including the lungs, kidneys, and brain. According to the medical report published by the World Health Organization (WHO) in 2020, approximately ten million people have been infected with tuberculosis. U-NET, a preferred method for detecting tuberculosis-like cases, is a convolutional neural network developed for segmentation in biomedical image processing.

Molecularly imprinted electrochemical biosensor for thrombin detection by comparing different monomers.

Investigating molecularly imprinted polymers (MIPs) in electrochemical biosensors for thrombin detection, an essential protein biomarker. Comparing different monomers to showcase distinct sensitivity, specificity and stability advantages. Dopamine, thionine and ethanolamine serve as monomers for MIP synthesis.

Can Endangered Biosimilar Markets be Rescued? The Need to Bridge Competing Interests for Long-Term Gain.

Market signals such as: (1) the limited number of biosimilars in the development pipeline, (2) the focus of biosimilar development on high-profit therapeutic areas only, and (3) the increase in the number of biosimilar discontinuations and withdrawals, are indicative of sustainability threats facing biosimilar markets in Europe. Two prominent factors that undermine sustainability are: competing interests between the various stakeholders and a preferential focus on short-term gains, disregarding future sustainability threats, hence the need for effective policies that create sustainable competition in biologic markets. Thus far, measures implemented to foster biosimilar adoption have not been necessarily complied with and have had mixed success.

Transversus Abdominis Plane Block VS. Local Wound Infiltration for Elective Minimally Invasive Cholecystectomy in Children: A Prospective Randomized Trial.

Background: The efficacy of transversus abdominis plane (TAP) block versus local anesthetic wound infiltration (LWI) in pediatric laparoscopic surgery is largely unknown. The objective of this study was to prospectively analyze this in minimally invasive cholecystectomy. We hypothesized that TAP block would be superior to LWI in terms of pain control and post-operative complications.

Peroxisome disruption alters lipid metabolism and potentiates antitumor response with MAPK-targeted therapy in melanoma.

Melanomas reprogram their metabolism to rapidly adapt to therapy-induced stress conditions, allowing them to persist and ultimately develop resistance. We report that a subpopulation of melanoma cells tolerate MAPK pathway inhibitors (MAPKis) through a concerted metabolic reprogramming mediated by peroxisomes and UDP-glucose ceramide glycosyltransferase (UGCG). Compromising peroxisome biogenesis, by repressing PEX3 expression, potentiated the proapoptotic effects of MAPKis via an induction of ceramides, an effect limited by UGCG-mediated ceramide metabolism.

Testing a Low-Intensity Single-Session Self-Compassion Intervention for State Body Shame in Adult Women: A Dismantling Randomized Controlled Trial.

State body shame is a risk factor for eating disorders, and self-compassion is emerging as a potentially effective treatment option in such cases. This study tested the efficacy of a brief (15-minute) self-compassion intervention in reducing state body shame. Using dismantling trial methodology, participants were randomly allocated to an active compassion condition (n = 23), an inactive control compassion condition (n = 23), or an educational control condition (n = 23).

"You Can't Be Too Skinny. You Can't Be Too Fat. I Don't Know What You Are Supposed To Be.": A qualitative focus group study exploring body image experiences of South Asian women in the UK.

British South Asian women may experience unique appearance pressures associated with their intersecting (racialised and gendered) identities; yet qualitative investigations of intersectional understandings of their body image are scarce. The aim of this study was to explore sociocultural factors influencing British South Asian women's body image using an intersectional framework. Seven focus groups were conducted with 22 women of South Asian heritage living in the UK between the age of 18 and 48 years old who were comfortable speaking in English.

Determinants of prescribing decisions for off-patent biological medicines in Belgium: a qualitative study.

Background: A competitive market for off-patent biologicals leads to more affordable and high-quality healthcare. In recent years, Belgium has been characterized by its low use of biosimilars and by its shifts from off-patent biologicals toward new alternative therapies. Yet, the prescribing decisions involved in these observations are poorly understood.

Applications of Behavioral Economics to Pharmaceutical Policymaking: A Scoping Review with Implications for Best-Value Biological Medicines.

Background And Objective: Pharmaceutical policies are generally based on the assumption that involved stakeholders make rational decisions. However, behavioral economics has taught us that this is not always the case as people deviate from rational behavior in rather predictable patterns. This scoping review examined to what extent behavioral concepts have already been applied in the pharmaceutical domain and what evidence exists about their effectiveness, with the aim of formulating future applications and research hypotheses on policymaking for best-value biologicals.

Comparing self-compassion versus body exposure for adult women with moderate to severe body dissatisfaction: A feasibility and pilot trial.

This study assessed the feasibility and effectiveness of two brief online interventions for body shame for women with moderate to severe negative body image, to inform the design of a future randomized controlled trial. The primary feasibility outcomes were recruitment, measure completion rates, retention rates and internet connection failure rates. The secondary pilot outcomes were change on clinical measures and state shame ratings during the interventions.