[Familial sarcoidosis 26 cases in 12 families (author's transl)].

The analysis of 12 families with 2 or more members suffering from sarcoidosis led a number of findings:--the increased prevalence of sarcoidosis in persons of mixed race from the French Caribbean), which would suggest the intervention of a racial component in the pathogenesis of sarcoidosis;--the rarity of cases where sarcoidosis affects more than 2 members of the same family;--the preponderance within the same family of subjects of identical sex, whether direct collaterals or a parent-child relationship (20 cases out of 26).--the importance of mother-child transmisstion (5 cases) as opposed to father-child transmission (1 case).

[Lcoc-regional sarcoid reaction. Sarcoidosis and malignant tumors].

On the basis of eight cases, the authors consider the relationship between sarcoidosis and malignant tumours. The development of a malignant tumour simultaneously or during the years following the onset of sarcoidosis is a rarely seen phenomenon. Only seven cases out of 580 of sarcoidosis were noted in this series.

[Erythema nodosum in sarcoidosis. 37 cases].

Erythema nodosum was seen in 37 out of 564 cases of sarcoidosis, i.e. 6.

[Gougerot-Sjögren syndrome in patients with sarcoidosis].

Three patients with eye and salivary dryness presenting the scintigraphic and histological features of Sjogren's syndrome and also suffering from sarcoïdosis, are reported. The authors stress the rarity of clinically indentifiable dry oculo-salivary syndromes whilst routine scintigraphy of the principle salivary glands using technetium 99 m often reveals altered salivary function. They consider that the primary feature in the development of this dry salivary syndrome consists of fibro-inflammatory lesions of the glandular interstitium, seen in specimens of the glands of the labial mucosae, which are sequelae of the initial sarcoid infiltration.

The problem of the treatment of sarcoidosis: Report of the Subcommittee on Therapy.

Stage I: Hilar Adenopathy With normal lung function observe, as it often resolves. With reduced lung function observe for 6-12 months. Treat if there is progression or persistence.

Lung water and capillary permeability in pulmonary sarcoid-like granulomatosis.

The subject of our research was the use of multiple indicators to study the lungs of rats during a pathological process induced by complete Freund's adjuvant (CFA). The parameters studied were extravascular water (idQwl), the capillary permeability of [14C]sucrose, and the unrecovered fraction of [3H5glucose. We ascertained that idQwl gives a valuable estimate of total pulmonary water (r=0.

Selective arteriography of the celiac artery in patients with thoracic sarcoidosis.

In this paper on hepatosplenic sarcoidosis the authors confirmed currently accepted concepts and further refined the examination of liver and spleen by selective arteriography of the celiac artery. In addition, they emphasized the frequency of hepatosplenomegaly in sarcoidosis as well as the speckled aspect of the parenchyma of both organs, which appeared dotted with innumerable small lacunae. This appearance was not strictly pathognomonic of sarcoidosis.

[Hepatosplenic sarcoidosis. Contribution of parenchymatous hepatosplenography by selective arteriography].

In this study of hepato-splenic sarcoidosis the authors, in addition to confirming the principle and commonly recognised features of the disease, stress the value of cataloguing the morphological changes, in the liver and spleen by selective arteriography of the coeliac trunk; increase in the frequency of recognition of hepatosplenomegaly; granular appearance of the parenchyma of both organs, which appear to be studded with a multitude of small lacunae, thus eliminating the homogeneous and uniformly opaque image seen normally. Seen in 28.5 p.

[Sclerosis of the intestinal lymphatic vessels].

Fibrosis of the intestinal lymphatic vessels, produced in one case by tuberculosis and, in the other, by appendicitis and peritonitis, caused blockage of the main lymphatic vessels causing, clinically, a protein-losing enteropathy similar to that noted in congenital lymphatic diseases of childhood. In the laboratory, there was noted a fall in serum protein, lipid and cholesterol. A fat absorption test was very abnormal showing a flat curve.