Primitive Resectable Small Bowel Cancer Clinical-Pathological Analysis: A 10-Year Retrospective Study in a General Surgery Unit.

Small bowel cancer is very rare; although the incidence of adenocarcinoma and other anatomopathological forms has increased recently, the diagnosis and treatment of this disease are still debatable because of the clinical heterogeneity and the absence of studies including a large number of patients. We performed a retrospective study over 10 years in which we analyzed the clinical, imaging, and anatomopathological data of 46 patients hospitalized in a surgery clinic and diagnosed with small bowel cancer (duodenum, jejunum, and ileum). After clinical assessment of these patients, including complications (occlusion, bleeding, and perforation), the CT scan established the diagnosis in over 90% of the cases of the complicated form of the disease.

Patterns and Emerging Trends in Acute Poisoning with Substances of Abuse Used for Recreational Purposes in Adolescents: A Six-Year Multicentre Study.

This six-year multicentre study investigated acute intentional poisoning with substances of abuse in adolescents to identify changes and patterns in substance use. Data from 562 adolescents were collected from three paediatric poison centres in Romania between January 2017 and December 2022. This study analysed the epidemiological and sociodemographic characteristics of the adolescents, including age, gender, place of residence, history of substance abuse, psychiatric history, and history of institutionalised care.

Epidemiology and Clinical Characteristics of Acute Plant Exposure in Patients Aged between 0 and 18 Years-A Six-Year Retrospective Study.

Background: Exposure to plants accounts for approximately 5% of human poisoning cases reported by poison control centers in North America and Europe. The aim of this study was to investigate acute plant poisoning in patients aged 0-18 years admitted to a Romanian pediatric poison center, focusing on epidemiological and clinical aspects.

Methods: A retrospective observational study was conducted between 2017 and 2022, analyzing medical records for demographic information, clinical features, biological findings, and outcomes.

Pancreatoduodenectomy for Malignant Solid Pseudopapillary Neoplasm in a Patient with Chronic Calcifying Pancreatitis, Rheumatoid Polyarthritis and Kidney Stones.

We present the case of a patient with rheumatoid polyarthritis treated in our department, with a long history of chronic calcifying pancreatitis which was incidentaly diagnosed during a renal colic with a pancreatic tumor. Pancreatoduodenectomy with lateral superior mesenteric vein resection was performed, the final pathological examination revealed a malignant solid pseudopapillary neoplasm with a positive lymph node. Clinical, surgical, pathological and a review of the literature are presented.

Giant Gallbladder Tumor, Unusual Cancer-Case Report and Short Review of Literature.

Background: Giant gallbladder is an uncommon condition that can result from a benign pathology and rarely presents with malignancy. Intracholecystic papillary-tubular neoplasm (ICPN) is a relatively new entity first described by V. Adsay in 2012 and included in the World Health Classification of Digestive System Tumours in 2019.

[Analysis of 62 cases of nosocomial staphylococcal meningitis admitted to the Iaşi Hospital of Infectious Diseases over a period of 21 years].

Aim: To analyze the clinical features, evolution and treatment of nosocomial staphylococcal meningitis admitted to Hospital of Infectious Diseases Iaşi between 1988 and 2007.

Material And Method: The data were gathered from the archive of Hospital of Infectious Diseases Iaşi. We studied the clinical and laboratory features of 62 cases of nosocomial staphylococcal meningitis admitted in the study period.

[Study of nosocomial bacillary meningitis admitted in the Clinic of Infectious Diseases Iaşi on a 20 years period].

Aim: To analyze the clinical features, etiology and evolution of nosocomial bacillary meningitis admitted to the Clinic of Infectious Diseases Iaşi between 1988 and 2007.

Material And Method: The data were gathered from the archive of the Clinic of Infectious Diseases Iaşi. We studied the clinical and laboratory features of 28 cases of nosocomial bacillary meningitis admitted in the study period.

[Microbiological aspects of subgingival plaque in patients with restorative treatments].

Objective: Our goal was to compare the microbial composition of subgingival plaque attached to different types of restorative materials.

Methods: The study included 19 patients. Samples of subgingival plaque were collected using sterile paper points.

[The impact of a sore throat score on clinical management of streptococcal angina].

Objective: To establish the validity and the role of a clinical sore throat score in clinical management of streptococcal angina on a first visit to a primary care provider.

Methods: This study included 168 patients. The sore throat score had 5 criteria: age, fever, absence of cough, tender anterior cervical nodes, tonsillar swelling or exudate.

[The distribution of anaerobic morpho-types in sub gingival plaque associated with periodontal disease].

The authors' goal has been to establish the distribution of anaerobic morpho-types in sub gingival plaque collected from patients with periodontal disease. The study included 26 patients. Samples of sub gingival plaque were transported in thioglycolate broth.

[Methods of microbiological diagnosis in periodontal disease].

Microbiological findings together with clinical and radiological diagnosis are essential for rationale use of antibiotics in periodontal disease. Methods used for microbiological diagnosis are: microscopy, cultivation, gas liquid chromatography, PCR, immuno-assays (ELISA, immunofluorescence), FISH. Each of them has some advantages and disadvantages related to cost, accessibility, sensitivity, duration.

Incidence and etiological agents of bacterial meningitis among children <5 years of age in two districts of Romania.

To expand upon the limited comprehensive population-based data for childhood bacterial meningitis in Eastern Europe, the present study was conducted in the Iasi and Constanta districts of Romania. From March 2000 through March 2002, children <5 years of age hospitalized for bacterial meningitis were enrolled in a prospective surveillance study. A total of 56 cases of bacterial meningitis were identified, including 37 due to Neisseria meningitidis (22 per 100,000 per year), 13 due to Haemophilus influenzae type b (7.

[Hemophilus influenzae meningitis- the experience of infectious diseases department between 1984-2001].

Our paper presents a clinico-biological and therapeutical study of the cases admitted in Infectious Diseases Hospital between January 1984-December 2001. We studied the records of all the patients that suffered from meningitis with Haemophilus influenzae. In above mentioned period 40 cases of Haemophilus influenzae meningitis was admitted; 6 patients (15%) died.

Sensitivity and resistance to antibiotics of Streptococcus pneumoniae involved in severe infections (1990-2000).

S. pneumoniae implicated in severe infections presents now a high frequency of the resistant strains to Penicillin G or multiresistance in the whole world. Our study on 136 strains of invasive pneumococcus isolated in the last 10 years showed a medium resistance to penicillin of 22.

[Clinical and biological study of acute diarrhea with mixed etiology in 48 patients].

Objectives: The study of incidence, clinical manifestation and treatment of acute diarrhea with mixed etiology.

Material And Method: Study of 48 patients with acute diarrhea with mixed etiology admitted in the Hospital of Infectious Diseases of Iaşi during 1995-1998.

Results: 12 cases (24%) were mixed bacterial infections with the following microorganisms associations: Salmonella + Shigella (10 cazuri); Salmonella + Yersinia enterocolitica (1 case); Salmonella + Rotavirus (1 case).

[Nosocomial staphylococcal meningitis].

Objective: Clinical, bacteriological and therapeutically study on iatrogenic staphylococcal meningitis.

Method: Retrospective analysis of 33 cases of iatrogenic staphylococcal meningitis admitted to the Hospital of Infectious Diseases of Iaşi in the interval 1988-1997.

Results: In the interval under study the recorded incidence was 1-5 cases per year.

[The clinical picture, treatment and prognosis of meningitis due to anaerobic and nonfermentative bacteria].

Objectives: The study of incidence, clinical manifestations and prognosis of meningitis with anaerobic and non-fermentative bacteria.

Material And Method: Retrospective study of 10 patients with severe forms of purulent meningitis admitted in the Hospital of Infectious Diseases of Iaşi, during 1.01.

[Postoperative and posttraumatic meningitis. Comments on 87 cases].

Iatrogenic and traumatic cerebromeningitis infections are increasing in frequency in the last two decades. Retrospective analysis of 87 patients iatrogenic and traumatic bacterial meningitis were admitted in the Clinic of Infectious Diseases from Iaşi between 1, 01, 1990-31, 12, 1994. Head trauma, lumbar punctures and iatrogenic meningitis infections were the causes cerebromeningitis infections.

[The streptococcal and staphylococcal toxic shock syndrome. Comments on 4 cases].

Between 1989 and 1995 in the Hospital of Infectious Diseases from Iaşi have been diagnoses 4 cases of streptococcal/staphylococcal toxic syndrome. Three patients have been grown up and one child. Two of them were immunocompromised hosts (cirrhosis, lung tuberculosis, alcoholism).

[The value of C-reactive protein for the differentiation of bacterial meningitis from viral meningitis].

In order to differentiate bacterial meningitis versus viral meningitis, we have comparatively tested the efficacy of the following tests: C-reactive protein (CRP), erythrocytes sedimentation rate (ESR), fever, level of glucose in cerebro-spinal fluid (CSF), glucose in CSF/glycemia ratio, number of white blood cells in peripheric blood, percentage of neutrophils in peripheric blood, level of proteins in CSF and number of nucleated cells in CSF for a group of 49 patients, both children and adults with central nervous system infection (37 patients with bacterial meningitis and 12 with viral meningitis) hospitalised between May 1993 and July 1994 in Clinical Hospital for Infectious Diseases in Iaşi. The mean value of CRP in bacterial meningitis patients was 8.78 mg%, contrasting with the mean value of CRP = 1.

[Scleromyxedema with laryngeal changes. Beneficial results of the treatment with mucopolysaccharidases].

We observed a case of scleromyxoedema with specific cutaneous lesions in a 62-year-old man. These lesions were associated with modifications of the central nervous system, latent thyroid failure, cardiovascular changes and myopathy, usual manifestations of this disease, but without paraproteinaemia. Unusual laryngeal manifestations were a dysphonia with chronic pseudomyxomatosis of the larynx.

Bioactive polymers: in vitro and in vivo study of controlled release neomycin.

Neomycin is coupled on xanthan-a polysaccharide of microbial biosynthesis produced by Xanthomonas campestris-through ionic complexation. The kinetics of neomycin release, in vitro, at pH = 8.2 is studied.

[Acute nosocomial bacterial meningitis. Apropos 27 cases].

Our series includes 27 patients with nosocomial meningitis (22 post neurosurgery and 5 post spinal puncture) of whom 15 with stated etiology (gram-negative bacilli and staphylococcus aureus in equal shares). Under the treatment with chloramphenicol + rifampicin + gentamicin a cure was obtained in 22 cases, improvement in 3 cases and 2 patients died.