Intracranial Outcomes of De Novo Brain Metastases Treated With Osimertinib Alone in Patients With Newly Diagnosed EGFR-Mutant NSCLC.

Introduction: Patients with EGFR-mutant NSCLC have a high incidence of brain metastases. The EGFR-directed tyrosine kinase inhibitor osimertinib has intracranial activity, making the role of local central nervous system (CNS)-directed therapies, such as radiation and surgery, less clear.

Methods: Patients with EGFR-mutant NSCLC and brain metastases who received osimertinib as initial therapy after brain metastasis diagnosis were included.

Cranial intraosseous meningioma: spectrum of neuroimaging findings with respect to histopathological grades in 65 patients.

The aim of this study was to determine various imaging features of intraosseous meningiomas (IOMs) and differentiate low-grade from high-grade tumors. The histopathologic evaluation revealed World Health Organization (WHO) grade I tumor in 56 (86%) patients, grade II in 8 (12%), and grade III in 1 (2%) patient. WHO grade I was considered low grade and II and III were designated as high grade.

A new preoperative radiological assessment in LeFort I surgery: anterior nasal spine-sphenoidal rostrum.

Objective: The aim of this study is to assess the distance between the anterior nasal spine and the sphenoidal rostrum related to the LeFort I surgery in a Turkish population sample.

Material And Methods: We retrospectively reviewed multidetector computerized tomography (MDCT) scans of 209 patients (134 males and 75 females). The images were obtained on a 64-MDCT scanner.

Diffusion tensor imaging in a child with hypertrophic olivary degeneration.

Hypertrophic olivary degeneration (HOD) is caused by disruptive lesions affecting components of the Guillain-Mollaret triangle (GMT). We present conventional magnetic resonance and diffusion tensor imaging (DTI) findings in a 6-year-old girl with HOD after surgery for a midbrain pilocytic astrocytoma. To our knowledge, this is the first dedicated DTI analysis of GMT in a child with HOD in the literature.

The many faces of fungal disease of the paranasal sinuses: CT and MRI findings.

The prevalence of fungal rhinosinusitis has increased worldwide over the last two decades. Fungal rhinosinusitis includes a wide variety of infections, from relatively innocent to rapidly fatal processes. Fungal infection may be one of the most challenging forms of sinonasal pathology to manage, especially the invasive forms, which have high mortality rates.

Initial experience of 3 tesla apparent diffusion coefficient values in differentiating benign and malignant thyroid nodules.

Purpose: To evaluate the role of diffusion-weighted magnetic resonance imaging (DWMRI) in differentiating benign and malignant thyroid nodules using a 3 Tesla (T) MRI scanner.

Materials And Methods: Twenty-eight nodules in 25 patients and 14 healthy control cases were included in the study. DWMRI was acquired with 6 b values with a 3T MRI scanner.

Radiologic assessment of the relationship between the maxillary artery and the lateral pterygoid muscle.

Objective: The course of the second part of the maxillary can vary among different races. The aim of this study was to evaluate the relation between the maxillary artery and the lateral pterygoid muscle in a white population sample on computed tomographic (CT) angiograms.

Materials And Methods: We retrospectively reviewed multidetector CT angiograms of 209 patients (134 men and 75 women).

Anterior spinal cord syndrome in a patient with Behçet's disease.

Although neurological involvement in Behçet's disease is not so uncommon, isolated spinal cord disease is quite rare and reported to be observed in about 2% of all cases with neurological involvement. Here we report a Behçet's patient with spinal cord disease presented with anterior spinal cord syndrome. This rare syndrome is caused by hypoperfusion of the anterior spinal artery and to our knowledge has not been previously reported in patients with Behçet's disease.

Feasibility of MR urography in patients with urinary diversion.

Introduction: The aims of this study were to determine the diagnostic value of MR urography and to compare the T2- and T1-weighted MR urography techniques in patients with urinary diversion.

Methods: We retrospectively reviewed 19 MR urograms in 14 patients (13 male and one female, 8-77 years old, mean age: 54.2) with urinary diversion.

Castleman disease as a giant parapharyngeal mass presenting with dysphagia.

A giant unilateral parapharyngeal mass from the skull base to the vocal folds is presented in this case. A 20-year-old man experiencing dysphagia for 4 years was admitted, and his magnetic resonance imaging and computed tomographic scans showed a giant parapharyngeal ellipsoid mass from the left jugular foramen to the vocal folds. Its craniocaudal length was 9 cm.

An unusual case of anterior and posterior laryngeal cleft together: combined cleft of larynx.

Congenital clefts of the larynx are rare and usually found dorsally. An anterior or ventral cleft of the larynx is extremely rare. Only a few patients with this defect have been reported in the literature.

HASTE diffusion-weighted MRI for the reliable detection of cholesteatoma.

Purpose: To assess the detection efficiency of Half-Fourier acquisition single-shot turbo spin-echo (HASTE) diffusion-weighted magnetic resonance imaging (MRI) for cholesteatoma.

Materials And Methods: A total of 21 patients with suspected primary (n=16) or recurrent cholesteatoma (n=5) underwent MRI in a 1.5 Tesla scanner using an adapted protocol for cholesteatoma detection that included a coronal HASTE diffusion-weighted MRI sequence.

Temporomandibular joint herniation into the external ear canal through foramen of Huschke.

Foramen of Huschke, which is also known as the foramen tympanicum, is an anatomical variation of the tympanic portion of the temporal bone. This foramen is located on the anteroinferior aspect of the external auditory canal, posteromedial to the temporomandibular joint. Herein, a rare case of foramen Huschke with a herniation of the soft tissues around the temporomandibular joint that result in severe otalgia and its treatment are presented.

Sciatic nerve compression due to femoral neck osteochondroma: MDCT and MR findings.

A 34-year-old man presented with a 15-month history of pain along the left sciatic nerve. Radiographs and computed tomography (CT) revealed an exostosis on the postero-inferior aspect of the left femoral neck. Ultrasonographic examination of left upper thigh and a pelvic magnetic resonance (MR) imaging showed an enlarged sciatic nerve adjacent to the exostosis.

Abscess formation as a complication of a ruptured urachal cyst.

The urachus is a midline tubular structure that extends upward from the dome of the bladder toward the umbilicus. This tubular structure normally involutes before birth, remaining as a fibrous band with no known function. Persistence of all or any portion of the fetal urachus results in several anomalies, the most common of which is the urachal cyst (Yu JS, Kim KW, Lee HJ, Lee YJ, Yoon CS, Kim MJ, Radiographics, 21:451-4611, 2001; Ohgaki M, Higuchi A, Chou H, Takashina K, Kawakami S, Fujita Y, Hagiwara A, Yamagishi H, Surg Today, 33:75-77, 2003).

Mechanical coil embolization of pulmonary arteriovenous malformations.

Purpose: To report our experience with mechanical coil embolization of pulmonary arteriovenous malformations.

Material And Methods: Coil embolization was performed in 6 men (mean age, 21.1 years; age range, 20-23 years) with pulmonary arteriovenous malformations between 1999 and 2004.

Bronchial artery embolization: experience with 10 cases.

Purpose: To report our experience with 10 cases of bronchial artery embolization (BAE).

Materials And Methods: The study included 18 cases (11 men and 7 women between 21 and 81 years of age, average 52 years), whose massive hemoptyses could not be controlled with conservative and bronchoscopic methods and were sent to the digital subtraction angiography unit between August 2002 and May 2004. Of these 18 cases, BAE was performed in 10 (7 men and 3 women between 21 and 78 years of age, average 54.

MRI findings of renal lymphangiectasia.

We present the case of a 20-year-old male with renal lymphangiectasia who presented with hypertension and hematuria. We discuss the role of magnetic resonance imaging (MRI) with gadolinium-enhanced MR urography in confirming the diagnosis, extensions of this rare benign entity, and associated conditions.

[Mechanical coil embolization of pulmonary arteriovenous malformations].

Purpose: To report our experience with mechanical coil embolization of pulmonary arteriovenous malformations (PAVM) MATERIAL AND METHODS: Coil embolizations were performed in 6 men (mean age 21.1, age range 20-23 years) with PAVM between 1999 and 2004. Five F Cobra catheters and various size coils were used for embolization.