Publications by authors named "Turan C"

Background: Idiopathic pulmonary fibrosis (IPF) is a progressive, deadly lung disease with several factors, including respiratory tract infections (RTI), for disease worsening. There's no comprehensive data on RTI incidence in IPF patients across different therapies, including antifibrotic (nintedanib or pirfenidone), investigative or placebo treatments.

Methods: A systematic search of databases Medline, EMBASE, Cochrane Central, Web of Science and Scopus was conducted on September 30th 2024 (PROSPERO registration number: CRD42023484213).

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  • - The study investigates the effectiveness of different balloon treatments after rotational atherectomy (RA) for calcified coronary lesions, focusing on whether modified balloons (MB) improve outcomes compared to plain balloon angioplasty (BA).
  • - A meta-analysis of nine studies involving 1,024 patients found no significant differences in major adverse cardiovascular events, all-cause mortality, or target lesion revascularization between the RA + BA and RA + MB groups overall.
  • - However, the analysis revealed that for patients with severely calcified lesions, the RA + MB group experienced significantly fewer major adverse cardiovascular events without increasing procedural complications.
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Progressive atelectasis regularly occurs during general anaesthesia; hence, positive end-expiratory pressure (PEEP) is often applied. Individualised PEEP titration may reduce the incidence of postoperative pulmonary complications (PPCs) and improve oxygenation as compared to fixed PEEP settings; however, evidence is lacking. This systematic review and meta-analysis was registered on PROSPERO (CRD42021282228).

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  • Genome-Wide Non-Invasive Prenatal Testing (GW-NIPT) can detect not just common chromosomal abnormalities but also rare autosomal trisomies and structural chromosomal issues, though data on their predictive value is limited.
  • The study analyzed 17 publications covering 740,076 cases to assess the accuracy of GW-NIPT for rare abnormalities, utilizing both confirmed and extended methodologies to define true positive cases.
  • Findings highlighted that T16, T22, and T15 had the highest rates of true positives, providing essential insights for genetic counseling and improving decision-making for patients and healthcare providers.
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: Vulvovaginal atrophy (VVA) significantly impacts the quality of life in breast cancer patients leading to symptoms like vaginal dryness, dyspareunia, and genital discomfort. Quality of life in this context is measured using validated scales like the Vaginal Health Index, Visual Analog Scale (VAS), and the Female Sexual Function Index (FSFI). : We performed a systematic review and meta-analysis to identify effective treatment options for VVA, including topical estrogen, systemic hormone therapy, vaginal DHEA, ospemifene, and non-hormonal methods like intravaginal laser therapy, moisturizers, and lubricants.

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Aims: Suboptimal device programming is frequent in non-responders to cardiac resynchronization therapy (CRT). However, the role of device optimization and the most appropriate technique are still unknown. The aim of our study was to analyse the effect of different CRT optimization techniques within a network meta-analysis.

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Fluid resuscitation during diabetic ketoacidosis (DKA) is most frequently performed with 0.9% saline despite its high chloride and sodium concentration. Balanced Electrolyte Solutions (BES) may prove a more physiological alternative, but convincing evidence is missing.

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Scabies, caused by the Sarcoptes scabiei var hominis mite burrowing into the skin, is a highly contagious disease characterized by intense nocturnal itching. Its global impact is considerable, affecting more than 200 million individuals annually and posing significant challenges to healthcare systems worldwide. Transmission occurs primarily through direct skin-to-skin contact, contributing to its widespread prevalence and emergence as a substantial public health concern affecting large populations.

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Background: This study aims to investigate the validity and reliability of the Turkish adaptation of the 16-item Risk of Relapse Assessment Scale (RRAS) for methamphetamine abusers.

Methods: A total of 160 patients diagnosed with methamphetamine use disorder were included in this study to evaluate the validity and reliability of the scale. The comparison of the relationship between the Risk of Relapse Assessment Scale, the Substance Craving Scale, and the Relapse Prediction Scale was also carried out.

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Introduction: The incidence of infertility caused by diminished ovarian reserve has become a significant problem worldwide. The beneficial effect of PRP treatment of the ovaries has already been described, but the high-level evidence of its effectiveness has not yet been proven.

Materials And Methods: A systematic search was performed in five databases, until March 12th, 2024.

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Background: Despite advancements in antibiotic therapy and resuscitation protocols, sepsis and septic shock remain major contributors to morbidity and mortality in children. We aimed to investigate the utility of soluble urokinase plasminogen activator receptor (suPAR) for the early detection of septic shock and to evaluate its accuracy in predicting mortality.

Methods: A prospective study was conducted in a tertiary pediatric emergency department (ED), enrolling patients diagnosed with the sepsis, severe sepsis, or septic shock.

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: Glucocorticoids may grant a protective effect against postoperative complications. The evidence on their efficacy, however, has been inconclusive thus far. We investigated the effects of preoperatively administered glucocorticoids on the overall postoperative complication rate, and on liver function recovery in patients undergoing major liver surgery.

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  • * An analysis of 15 articles with nearly 2,500 patients found that LGE positivity is linked to a significantly higher SCD risk, especially in patients with non-ischemic conditions.
  • * Although LGE positivity indicates higher SCD risk, the difference in outcomes for CRT candidates based on LGE status was not statistically significant, suggesting that heart remodeling may play a role in this patient group.
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  • Cryotherapy has been shown to effectively relieve pain and reduce inflammation in ingrown toenails, but its specific impact on juvenile cases was previously under-researched.
  • In a study involving adolescents aged 12 to 16 with unilateral ingrown toenails, liquid nitrogen was applied to the nail fold, resulting in a high efficacy rate of 91.7% as reported by physicians.
  • While 54.5% of patients maintained improvement after 6 months, there was a notable difference in the success rate based on the size of granulation tissue, and 83.3% of patients experienced satisfactory symptom relief even without complete regression of the tissue.
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This study examined the age distribution and growth characteristics of the striped eel catfish (), which is an invasive alien species in the eastern Mediterranean. A total of 1,011 samples were collected from Iskenderun Bay (Turkey), with lengths ranging from 5.1 to 16.

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Introduction: To date various oral manifestations in patients with coronavirus disease 2019 (COVID-19) have been reported.

Objectives: In the present study, we investigated the relationship between Polymerase Chain Reaction (PCR) positivity and oral signs in patients with suspected COVID-19.

Methods: A total of 383 patients who presented to the emergency department for the first time with any symptoms associated with COVID-19 were included in the study.

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The field of deep learning is rapidly advancing and impacting various industries, including banking. However, there are still challenges when it comes to accurately identifying the denomination of currencies, especially when dealing with issues like variation within the same class of currency and inconsistent lighting conditions. One notable problem is the lack of available data for Kazakhstan's currency.

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Critically ill patients are at risk of developing acute liver dysfunction as part of multiorgan failure sequelae. Clearing the blood from toxic liver-related metabolites and cytokines could prevent further organ damage. Despite the increasing use of hemoadsorption for this purpose, evidence of its efficacy is lacking.

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Background: Acute respiratory distress syndrome (ARDS) is often a consequence of a dysregulated immune response; therefore, immunomodulation by extracorporeal cytokine removal has been increasingly used as an adjuvant therapy, but convincing data are still missing. The aim of this study was to investigate the effects of adjunctive hemoadsorption (HA) on clinical and laboratory outcomes in patients with ARDS.

Methods: We performed a systematic literature search in PubMed, Embase, CENTRAL, Scopus, and Web of Science (PROSPERO: CRD42022292176).

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Objective: To compare the assessment of intra-ovarian stromal vascularity through transabdominal ultrasonography with colour Doppler imaging, power Doppler imaging, colour superb microvascular imaging and monochrome superb microvascular imaging in polycystic ovary syndrome cases.

Methods: The retrospective cross-sectional study was conducted at the Obstetrics and Gynaecology outpatient department of the Usak Training and Research Hospital, Turkey, from April 11 to June 18, 2018, and comprised grayscale colour Doppler imaging, power Doppler imaging, colour superb microvascular imaging and monochrome superb microvascular imaging of women with polycystic ovary syndrome. The recorded video images were evaluated by three radiologists and rated through consensus decision.

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Background: Appropriate antibiotic (AB) therapy remains a challenge in the intensive care unit (ICU). Procalcitonin (PCT)-guided AB stewardship could help optimize AB treatment and decrease AB-related adverse effects, but firm evidence is still lacking. Our aim was to compare the effects of PCT-guided AB therapy with standard of care (SOC) in critically ill patients.

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Objective: The aim of this retrospective cohort study was to investigate complete blood count parameters in patients with Behçet's disease (BD) who present with oral ulcers and patients with recurrent aphthous stomatitis (RAS) in order to determine whether they could be used as discriminatory biomarkers.

Patients And Methods: This study was conducted between January 2019 and January 2023. The study population consisted of three groups: patients with BD who had oral ulcer manifestation (n=85, BD-Group), patients with idiopathic RAS (n=186, RAS-Group) and healthy controls (n=90, HC-Group).

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Recurrent oral ulcers, which are the first and most common manifestation of Behçet's disease (BD), have several etiological causes but are often idiopathic and known as recurrent aphthous stomatitis (RAS). In recent years, publications have drawn attention to the fact that whole-wall thickness (WWT) and intima-media thickness (IMT) measurements of the common femoral vein (CFV) may be useful in the diagnosis of BD, which are independent of organ involvement. In this study, the usefulness of the WWT and IMT of the CFV measured by venous Doppler ultrasound (US) was investigated in differentiating BD presenting with oral ulcers from RAS.

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