Publications by authors named "Tuppin P"
Epidemiology of cardiovascular risk factors: Behavioural risk factors.
Arch Cardiovasc Dis
December 2024
Article Synopsis
- * A significant portion of the French population engages in unhealthy behaviors: one-third smoke, 71.7% don’t consume enough fruits and vegetables, and many fail to meet physical activity guidelines.
- * Although there are some improvements, like increased physical activity in men and reduced smoking rates, serious concerns remain, especially as women's health behaviors begin to mirror those of men, highlighting the need for enhanced prevention efforts.
Article Synopsis
- The study reviews the management and outcomes of stroke cases in France, revealing significant data from the year 2022 after nearly a decade of a national stroke plan.
- In total, 122,422 adults were hospitalized for stroke, with stark variations in care based on geographic and socioeconomic factors, and low rates of advanced treatments like mechanical thrombectomy.
- The findings indicate high mortality rates within a year post-stroke and call for improved prevention strategies, better public awareness of stroke symptoms, and enhanced accessibility to stroke care services.
Epidemiology of aortic and peripheral arterial diseases in France.
Arch Cardiovasc Dis
December 2024
Background: Peripheral arterial diseases (PADs) account for much of the morbidity and hospitalizations experienced by patients with cardiovascular disease. Epidemiological data on these diseases are lacking in France.
Aims: To describe the epidemiology of aortic diseases (aneurysm and dissection) and PADs in France in 2022.
Background: Demographic changes and improvements in the diagnosis and treatment of valvular heart diseases (VHDs) have led to changes in its epidemiological profile.
Aims: To describe the epidemiology of VHD in France in 2022.
Methods: Adults hospitalized due to VHD in 2022 were identified from the French National Health Data System and categorized by type of VHD on the basis of hospital diagnoses and interventions.
Background: Few epidemiological data are available for venous thromboembolism (VTE) at French national and subnational levels.
Aims: To quantify VTE events in France in 2022 and describe the features of hospital management and outcomes.
Methods: Adults hospitalized for a VTE as the primary reason for hospitalization or treatment in a medical unit in 2022 were identified from medical administrative data.
The prevalence of depressive and anxiety disorders is higher in women than in men. In contrast, there is still no clear consensus on the existence of sex-related differences in the effectiveness of antidepressant treatments for these disorders. This real-world study used filled prescription sequences to compare antidepressant medications between women and men at a medication level according to their acceptability (ie, combination of efficacy and tolerability).
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- - In 2022, France recorded 242,227 hospitalizations due to ischaemic heart disease (IHD), affecting 5.6% of the adult population, with a significant mortality rate of 4.8% of all deaths being IHD-related.
- - Patients hospitalized for IHD had an average age of 69.3 years, with 29% being women; there was a high prevalence of cardiovascular risk factors, and many underwent interventions like percutaneous coronary interventions.
- - One year post-hospitalization, 29.9% of patients were rehospitalized for IHD, and 9.3% died from all causes, highlighting the need for improved prevention strategies for IHD in France.*
Article Synopsis
- - In 2022, France recorded 181,178 hospitalizations for heart failure (HF), yielding a prevalence rate of 2.6% among adults, while hospitalization rates were notably higher in socioeconomically deprived areas.
- - The overall hospital fatality rate for HF was 10.2%, with a significant increase to 34.0% within a year; however, only 20.1% of patients were admitted to rehabilitation within six months.
- - The findings highlight the need for improved cardiovascular prevention strategies and adaptations in healthcare services across different regions in France, emphasizing the importance of better adherence to treatment guidelines.
Article Synopsis
- Heart rhythm and conduction disorders vary in severity and can be benign or life-threatening, with a focus on their epidemiology in France.
- A study analyzed hospitalization data from 2022 and mortality from 2021 to assess the prevalence of three main conditions: atrial fibrillation/flutter, conduction disorders, and ventricular tachycardia/cardiac arrest.
- Findings revealed over 2.7 million individuals impacted by these disorders as of January 2023, with significant hospitalization rates and a concerning 44% mortality rate for those hospitalized due to ventricular tachycardia/cardiac arrest.
Epidemiology of cardiovascular risk factors: Non-behavioural risk factors.
Arch Cardiovasc Dis
December 2024
Article Synopsis
- Cardiovascular disease is the leading cause of death globally and a major concern in France, heavily influenced by modifiable risk factors like obesity, diabetes, hypertension, and high cholesterol levels.
- In 2015, significant prevalence rates for these conditions were reported among adults aged 18-74, with obesity at 17.2% and diabetes at 7.4%, yet awareness of these conditions was low among those affected.
- A push for better prevention methods, especially through nutrition and education, is essential to tackle these cardiovascular risk factors, with a noted importance on also addressing women's specific health issues that impact cardiovascular risk.
Article Synopsis
- Cardiovascular diseases (CVDs) and strokes are the top causes of death globally, motivating a comprehensive study on their incidence and hospitalizations in France for adults and pregnant women.
- In 2022, over 1.2 million adults were hospitalized for CVD, with a higher rate in men and those of lower socioeconomic status, while CVD caused approximately 138,137 adult deaths in 2021.
- Among children, congenital heart defects affected 3,876 infants in early 2022, and for pregnant women between 2010-2018, there were 1,261 strokes and 225 acute coronary syndromes, highlighting the urgent need for better prevention and management strategies for CVD.
Article Synopsis
- The study examined cerebral venous thrombosis (CVT) characteristics in elderly patients (65 years and older) across nine hospitals in the Paris-Ile-de-France region from 2011 to 2021.
- Researchers found that the annual incidence of CVT in this demographic was lower compared to the national average, with headaches and focal deficits being the most common initial symptoms.
- The results indicated that elderly patients had a distinct clinical profile, with higher rates of underlying conditions like cancer and a worse prognosis than younger adults, highlighting the need for specialized care in this age group.
Article Synopsis
- - This study analyzed patient survival rates following the surgical removal of high-grade gliomas (HGG) and identified key factors influencing outcomes using data from a national health database in France.
- - A total of 1,438 patients were examined, revealing a median overall survival (OS) of 1.69 years, with one-year, two-year, and five-year survival rates at 78.5%, 40.3%, and 11.8%, respectively.
- - Factors positively affecting survival included being female, younger age at surgery, completing over six months of chemoradiotherapy with temozolomide, and undergoing redo surgery for recurrence.
Aims: To evaluate the impact of cardiac rehabilitation (CR) on optimization of secondary prevention treatments for acute coronary syndrome (ACS), medication persistence, medical follow-up, rehospitalization, and all-cause mortality.
Methods And Results: The National Health Insurance database was used to identify all patients hospitalized for ACS in France in 2019 and those among them who received CR. Patients' characteristics and outcomes were described and compared between CR and non-CR patients.
Background: Infection may trigger pediatric arterial ischemic stroke (PAIS), notably when related to focal cerebral arteriopathy. Community- and individual-level nonpharmaceutical interventions during the COVID-19 pandemic resulted in a major decrease in pediatric viral infections. We explored the consequences on the incidence of PAIS.
View Article and Find Full Text PDFBackground: This study was designed to identify factors associated with at least one emergency department (ED) visit and those associated without consultation by a general practitioner or paediatrician (GPP) before ED visit. Levels of annual consumption of healthcare services as a function of the number of ED visit were reported.
Methods: This retrospective study focused on children < 18 years of age living in mainland France and followed for one-year after their birth or birthday in 2018.
Background: Cardiac rehabilitation after an acute coronary syndrome is recommended to decrease patient morbidity and mortality and to improve quality of life.
Aims: To describe time trends in the rates of patients undergoing cardiac rehabilitation after an acute coronary syndrome in France from 2009 to 2021, and to identify possible disparities.
Methods: All patients hospitalized for acute coronary syndrome in France between January 2009 and June 2021 were identified from the national health insurance database.
Few regular national clinical data are available for individuals with Down's syndrome (IDS) bearing in mind that they are subject to countries variations in medical termination of pregnancy and screening. Individuals < 65 in 2019 were selected in view of the low number of older IDS. Thus, 98% of 52.
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- The study evaluates the effectiveness of the Healthcare Expenditures and Conditions Mapping (HECM) algorithm in identifying various health conditions, specifically for patients with end-stage kidney disease (ESKD) in France.
- A total of 5,971 patients were analyzed, finding that 81% were accurately identified as having ESKD in both datasets, with diabetes showing the highest accuracy.
- The HECM performed well overall but struggled with cancer identification, suggesting further validation is needed for broader use in different patient populations.
Aims: To estimate the time trends in the annual incidence of patients hospitalized for acute coronary syndrome (ACS) in France from 2009 to 2021 and to analyse the current sex and social differences in ACS, management, and prognosis.
Methods And Results: All patients hospitalized for ACS in France were selected from the comprehensive National Health Insurance database. Age-standardized rates were computed overall and according to age group (over or under 65 years), sex, proxy of socioeconomic status, and ACS subtype [ST-segment elevation (STSE) and non-ST-segment elevation].
On the occasion of the 20th anniversary of the REIN (French Renal Epidemiology and Information Network), a summary work on the contributions of the national French ESKD register was carried out. On the issue of its link with health authorities, the following key messages were retained. One of the purposes of REIN is to contribute to a better understanding about patient management and its evolution, and thus to be called upon to develop health strategies aimed at improving the prevention and treatment of chronic renal failure.
View Article and Find Full Text PDFBackground: Nationwide data for children for short-stay hospitalisation (SSH) and associated factors are scarce. This retrospective study of children in France < 18 years of age followed after their birth or birthday in 2018 focused on at least one annual SSH, stay < 1 night or ≥ 1 night, or 30-day readmission ≥ 1 night.
Methods: Children were selected from the national health data system (SNDS), which includes data on long-term chronic disease (LTD) status with full reimbursement and complementary universal coverage based on low household income (CMUC).
This study aimed to describe the health status of children and how social deprivation affects their use of healthcare services and mortality. Children living in mainland France were selected from the national health data system (SNDS) on their date of birth or birthday in 2018 (< 18 years) and followed for one year. Information included data on healthcare reimbursements, long-term chronic diseases (LTDs) eligible for 100% reimbursement, geographic deprivation index (FDep) by quintile (Q5 most disadvantaged), and individual complementary universal insurance (CMUc) status, granted to households with an annual income below the French poverty level.
View Article and Find Full Text PDFEnd-stage kidney disease (ESKD) is associated with a substantial economic burden. In France, the cost of care for such patients represents 2.5% of the total French healthcare expenditures but serves less than 1% of the population.
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