Publications by authors named "Tuominen J"

Article Synopsis
  • The study aims to improve predictions of disease outcomes for breast cancer patients undergoing neoadjuvant treatment (NAT) by analyzing clinical and histopathological data.
  • Researchers evaluated a cohort of 257 Finnish breast cancer patients over 13 years, identifying significant prognostic factors and previously overlooked histological features that correlate with treatment response and survival.
  • The findings suggest the importance of re-assessing biomarkers post-treatment and developing personalized surveillance and treatment strategies based on comprehensive evaluations of patient data and risk factors.
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  • Ideal partner preferences shape key insights in human mating research, but recent studies face issues such as inconsistent analysis methods and varying findings across different populations.
  • A large-scale study involving 10,358 participants from 43 countries revealed significant effects of preference matching, particularly when analyzing traits collectively, with some traits showing minimal impact on partner evaluations.
  • The research also highlighted gender differences, where both men and women misjudged the importance of traits like attractiveness and earning potential in their stated preferences compared to actual revealed preferences.
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  • The COVID-19 pandemic and its associated restrictions have led to an increase in domestic violence (DV) and may deter victims from seeking help.
  • A study involving shelter clients, community care service users, and professionals revealed that experiences of violence, particularly psychological, controlling, and financial, intensified during the pandemic.
  • The research highlights coercive control as a significant issue for vulnerable groups such as intimate partners, children, and migrants, aiming to enhance support services for pandemic-related DV.
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Previous research indicates that the COVID-19 pandemic has affected dreaming negatively. We compared 1132 dreams collected with prospective two-week dream diary during the pandemic to 166 dreams collected before the pandemic. We hypothesized that the pandemic would increase the number of threatening events, threats related to diseases, and the severity of threats.

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Background And Objectives: The incidence rate of Parkinson disease (PD) has been increasing rapidly during the past years. Yet, no treatments exist to prevent or slow the progression of the disease. Moreover, we are unable to detect early disease stages during which intervention with disease-modifying therapies is most likely to succeed.

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Purpose: Social work clients often face complex financial problems. We have developed a financial social work intervention, FinSoc, to increase financial literacy and economic self-efficacy and reduce financial anxiety among parents with financial problems in Finland. The aim of this pilot randomized controlled trial is to explore the feasibility, acceptability, and preliminary effectiveness of the intervention.

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The current evidence suggests that higher levels of crowding in the Emergency Department (ED) have a negative impact on patient outcomes, including mortality. However, only limited data are available about the association between crowding and mortality, especially for patients discharged from the ED. The primary objective of this study was to establish the association between ED crowding and overall 10-day mortality for non-critical patients.

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Resting-state fMRI is an increasingly popular alternative to task-based fMRI. However, a formal quantification of the amount of information provided by resting-state fMRI as opposed to active task conditions about neural responses is lacking. We conducted a systematic comparison of the quality of inferences derived from a resting-state and a task fMRI paradigm by means of Bayesian Data Comparison.

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  • The study explores how COVID-19-related concerns and anxiety impact people's mind-wandering and dreaming, specifically looking at the emotional quality of these experiences.
  • Researchers used daily logs over two weeks from 172 individuals to track connections between daily worries and the affect experienced during mind-wandering and dreaming.
  • Results showed that poor sleep quality led to more negative feelings in dreams, while consistent COVID-19 worry was linked to increased negative affect in both waking daydreams and nighttime dreams.
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Emergency department (ED) crowding is a well-recognized threat to patient safety and it has been repeatedly associated with increased mortality. Accurate forecasts of future service demand could lead to better resource management and has the potential to improve treatment outcomes. This logic has motivated an increasing number of research articles but there has been little to no effort to move these findings from theory to practice.

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Conviction Narrative Theory (CNT) is conceptually so multifaceted as to make critical evaluation difficult. It also omits one course of action: Active engagement with the world. Parsing the developmental and mechanistic processes within CNT would allow for a rigorous research programme to put the account under test.

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Primary stressors are direct outcomes of extreme events (e.g., viruses, floodwater) whereas secondary stressors stem from pre-disaster life circumstances and societal arrangements (e.

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  • There is limited research on how different types of beta2-adrenoreceptor (β2AR) agonists impact the risk of developing Parkinson's disease in various groups of patients.
  • A prospective study in Norway found that exposure to short-, long-, and ultra-long-acting β2AR agonists was linked to a lower risk of Parkinson's disease, with ultraLABA showing the strongest protective effect.
  • After adjusting for factors like education and comorbidities, β2AR agonists remained inversely associated with Parkinson's risk, unlike other similar medications, indicating the need for more studies on these drugs.
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Background: The isokinetic dynamometry is considered a gold standard in muscle strength testing. The reliability of lower limb isokinetic strength measurements has not been thoroughly evaluated.

Objective: To examine the test-retest reliability of isokinetic ankle plantar and dorsiflexion, ankle inversion and eversion, knee extension and flexion and hip abduction and adduction strength in physically active adults using Biodex System 4 Pro.

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This article's main contributions are twofold: 1) to demonstrate how to apply the general European Union's High-Level Expert Group's (EU HLEG) guidelines for trustworthy AI in practice for the domain of healthcare and 2) to investigate the research question of what does "trustworthy AI" mean at the time of the COVID-19 pandemic. To this end, we present the results of a post-hoc self-assessment to evaluate the trustworthiness of an AI system for predicting a multiregional score conveying the degree of lung compromise in COVID-19 patients, developed and verified by an interdisciplinary team with members from academia, public hospitals, and industry in time of pandemic. The AI system aims to help radiologists to estimate and communicate the severity of damage in a patient's lung from Chest X-rays.

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Aim: The aim of this study was to compile, assess and synthesise empirical research on violence by social and healthcare clients or patients against staff and its connections to staff's well-being at work, implementation of work and activities of leaders related to it.

Background: Workplace violence against social and healthcare staff is a global and daily problem. One in three employees encounters violence from patients or clients and the risk of this is 16 times higher compared to other professions.

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Background And Objective: Emergency Department (ED) overcrowding is a chronic international issue that is associated with adverse treatment outcomes. Accurate forecasts of future service demand would enable intelligent resource allocation that could alleviate the problem. There has been continued academic interest in ED forecasting but the number of used explanatory variables has been low, limited mainly to calendar and weather variables.

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Gene fusions can act as oncogenic drivers and offer targets for cancer therapy. Since fusions are rare in colorectal cancer (CRC), their universal screening seems impractical. Our aim was to investigate gene fusions in 62 CRC cases with deficient MLH1 (dMLH1) and BRAFV600E wild-type (wt) status from a consecutive real-life series of 2079 CRCs.

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Background And Objectives: Optimal margins for ductal carcinoma in situ (DCIS) remain controversial in breast-conserving surgery (BCS) and mastectomy. We examine the association of positive margins, reoperations, DCIS and age.

Methods: A retrospective study of histopathological reports (4489 patients).

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In order to gain a better understanding of what happens during the COVID-19 pandemic to those who were previously traumatized, this study investigated perceived stress and severity of PTSD symptoms during the COVID-19 pandemic in people who experienced the 1992-1995 war in Bosnia and Herzegovina. It was also examined how reminders of past trauma and loneliness instigated by the COVID-19 crisis relate to current stress and PTSD symptoms. The sample consisted of 123 participants (74.

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Affective experiences occur across the wake-sleep cycle-from active wakefulness to resting wakefulness (i.e., mind-wandering) to sleep (i.

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Based on the Social Simulation Theory of dreaming (SST), we studied the effects of voluntary social seclusion on dream content and sleep structure. Specifically, we studied the Compensation Hypothesis, which predicts social dream contents to increase during social seclusion, the Sociality Bias - a ratio between dream and wake interactions - and the Strengthening Hypothesis, which predicts an increase in familiar dream characters during seclusion. Additionally, we assessed changes in the proportion of REM sleep.

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Can the brain be shifted into a different state using a simple social cue, as tests on highly hypnotizable subjects would suggest? Demonstrating an altered global brain state is difficult. Brain activation varies greatly during wakefulness and can be voluntarily influenced. We measured the complexity of electrophysiological response to transcranial magnetic stimulation in one 'hypnotic virtuoso'.

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Background: Emergency departments (EDs) worldwide have been in the epicentre of the novel coronavirus disease (COVID-19). However, the impact of the pandemic and national emergency measures on the number of non-COVID-19 presentations and the assessed acuity of those presentations remain uncertain.

Methods: We acquired a retrospective cohort containing all ED visits in a Finnish secondary care hospital during years 2018, 2019 and 2020.

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