Body mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritis.

Background: There is a growing interest concerning the relationship between obesity and several medical conditions and inflammation. Nevertheless, there is a lack of studies regarding body mass index (BMI) among patients with juvenile idiopathic arthritis (JIA). Our aim was to investigate the impact of BMI on health-related quality of life (HRQoL) measured with a 36-Item Short Form Survey (SF-36), disease activity, and disability in young adults with JIA.

tumor vaccination by percutaneous ablative therapy and its synergy with immunotherapeutics: An update on combination therapy.

Percutaneous tumor ablation is now a widely accepted minimally invasive local treatment option offered by interventional radiology and applied to various organs and tumor histology types. It utilizes extreme temperatures to achieve irreversible cellular injury, where ablated tumor interacts with surrounding tissue and host tissue remodeling and inflammation, clinically manifesting as post-ablation syndrome. During this process, tumor vaccination occurs, in which tumor neoantigens are released from ablated tissue and can prime one's immune system which would favorably affect both local and remote site disease control.

Abdominal pain in Finnish young adults with juvenile idiopathic arthritis.

Objectives: Abdominal pain (AP) is a common feature in the general population. However, in patients with juvenile idiopathic arthritis (JIA) AP has scantily been studied. Among other reasons, gastrointestinal symptoms may present as side effects due to the medical treatment of JIA.

The Urban American Indian Traditional Spirituality Program: Promoting Indigenous Spiritual Practices for Health Equity.

Beginning in 2009, Detroit's urban American Indian health center entered into a collaborative and participatory partnership with a university research team. The purpose of the partnership was to incorporate Indigenous traditional healing practices into the health and wellness services at this center. Following extensive consultation with stakeholders at the center, we were commissioned by local decision-makers to develop a program tailored for members of the urban American Indian community that would introduce and orient these individuals to meaningful participation in Indigenous traditional spirituality.

High rates of subglottic stenosis seen in African-American children admitted with severe croup to hospitals in the United States between 2003 and 2013.

Background: To assess whether differences exist in the epidemiology and the treatment of croup with respect to gender, race, income and geographical location.

Methods: Retrospective weighted analysis of patients under 19 admitted with a diagnosis of croup with a subcohort of patients requiring intubation or diagnostic bronchoscopy from the National Inpatient Sample and Kids' Inpatient Database from 2003 to 2013. ICD-9 codes and demographics were analyzed; cross tabulations and linear regression modeling were performed.

Improving Ultrasound Detection of Uterine Adenomyosis Through Computational Texture Analysis.

The purpose of our study was to determine if a textural analysis metric can be implemented to improve diagnosis of adenomyosis by ultrasound.We retrospectively identified 38 patients with a magnetic resonance imaging (MRI) diagnosis of uterine adenomyosis that also had a pelvic ultrasound within 6 months. We also identified 50 normal pelvic ultrasound examinations confirmed by a normal pelvic MRI within 6 months as a control group.

Addressing Data Inequities in American Indian Communities Through an Environmental Public Health Tracking Pilot Project.

National and state surveillance systems identify American Indians/Alaska Natives inconsistently and often inaccurately within their data sets. Consequently, communities may not be represented with data at the level of geography needed. Collecting and presenting environmental and health-related data to the public are done by state Tracking Networks.

Teaching Tradition: Diverse Perspectives on the Pilot Urban American Indian Traditional Spirituality Program.

Many urban American Indian community members lack access to knowledgeable participation in indigenous spiritual practices. And yet, these sacred traditional activities remain vitally important to their reservation-based kin. In response, our research team partnered with an urban American Indian health center in Detroit for purposes of developing a structured program to facilitate more ready access to participation in indigenous spiritual knowledge and practices centered on the sweat lodge ceremony.

Quantitative analysis of ultrasound images for computer-aided diagnosis.

We propose an adaptable framework for analyzing ultrasound (US) images quantitatively to provide computer-aided diagnosis using machine learning. Our preliminary clinical targets are hepatic steatosis, adenomyosis, and craniosynostosis. For steatosis and adenomyosis, we collected US studies from 288 and 88 patients, respectively, as well as their biopsy or magnetic resonanceconfirmed diagnosis.

Oral guar gum, a gel-forming dietary fiber relieves pruritus in intrahepatic cholestasis of pregnancy.

Background: Guar gum is a gel-forming fiber, which increases fecal elimination of bile acids. It may therefore be beneficial in the treatment of intrahepatic cholestasis of pregnancy.

Methods: Forty-eight patients with intrahepatic cholestasis of pregnancy were randomized double-blind to receive either guar gum or placebo until delivery.

Manufacture of polyalkylcyanoacrylate nanoparticles with pilocarpine and timolol by micelle polymerization: factors influencing particle formation.

Nanoparticles with pilocarpine and timolol were produced by micelle polymerization. The influence of manufacturing temperature, type of monomer, drug concentration and ethylcyanoacrylate concentration on the particle size were investigated with a Coulter Nano Sizer. The nanoencapsulation succeeded only with the pilocarpine or timolol base, not with the salts of these drugs.

Occurrence of symptomatic knee osteoarthrosis in rural Finland: a prospective follow up study.

All visits to physicians in the Orivesi Region Federation of Municipalities for Public Health Work in Finland paid due to symptomatic osteoarthrosis of the knee joint were prospectively recorded over a period of one year. Two hundred and thirty four visits were made, accounting for 0.63% of all visits.