Classification of glucose-level in deionized water using machine learning models and data pre-processing technique.

Accurate monitoring of glucose levels is essential in the field of diabetes detection and prevention to ensure appropriate treatment planning. Conventional blood glucose monitoring methods, although widely used, are intrusive and frequently result in discomfort. This study investigates the use of Raman spectroscopy as a non-invasive method for estimating glucose concentrations.

Stability and magnetic properties of transition metal (V, Cr, Mn, and Fe) doped cobalt oxide clusters: a density functional theory investigation.

Co TMO ( = 6-8), (TM = V, Cr, Mn, and Fe) clusters are investigated using density functional theory calculations. The transition metal atoms preferentially replace one Co atom at sites where the number of metal-oxygen bonds is maximized, forming more stable structures. The evaporation of a Co atom is the most fragile dissociation channel for both pure and doped species.

Dimerization of the Aβ under the Influence of the Gold Nanoparticle: A REMD Study.

Advances in Alzheimer's disease (AD) are related to the oligomerization of Amyloid β (Aβ) peptides. Therefore, alteration of the process can prevent AD. We investigated the Aβ dimerization under the effects of gold nanoparticles using temperature replica-exchange molecular dynamics (REMD) simulations.

Association between Maternal and Fetal Genetic Variants and Preeclampsia: Evidence from a Meta-Analysis.

The objective of this meta-analysis was to evaluate the association between maternal and fetal genetic variants and the risk of preeclampsia, a pregnancy-related condition that affects women. Despite the unclear role of these genetic factors in the development of preeclampsia, this analysis aimed to provide insights into the potential contributing factors. An electronic search of online databases was conducted to identify relevant studies.

The Relationship Between Smooth Endoplasmic Reticulum Clusters in Metaphase II Oocytes and Embryological and Birth Outcomes in Infertile Couples.

Background: To assess the relationship between oocytes with smooth endoplasmic reticulum cluster (SERc) and embryological and birth outcomes in infertile couples.

Methods: This was a descriptive study that included 231 infertile patients undergoing in vitro fertilization (IVF) with a total of 2447 mature oocytes (MII), of which 279 oocytes with SERc(+) from 100 patients, the remaining 2168 oocytes with SERc(-). Oocytes were evaluated for the presence or absence of the SERc simultaneously with intracytoplasmic sperm injection at 200x magnification using inverted microscopy - Observe D1.

Preimplantation Genetic Diagnosis of Androgen Resistance Syndrome Caused by Mutation on the Gene in Vietnam.

Background: Androgen resistance syndrome or androgen insensitivity syndrome (AIS - Androgen Insensitivity Syndrome, OMIM 300068) is an X-linked recessive genetic syndrome causing disorders of sexual development in males. This disease is caused by mutations in the AR gene located on the X chromosome, which encodes the protein that structures the androgen receptor, with the role of receiving androgens. Mutation of the AR gene causes complete or partial loss of androgen receptor function, thereby androgen not being obtained and exerting its effect on target organs, resulting in abnormalities of the male reproductive system due to this organ system, differentiating towards feminization under the influence of estrogen.

Unraveling Hydrogen Adsorption on Transition Metal-Doped [MoS] Clusters: Insights from Density Functional Theory Calculations.

Molecular and dissociative hydrogen adsorption of transition metal (TM)-doped [MoS] atomic clusters were investigated using density functional theory calculations. The introduced TM dopants form stable bonds with S atoms, preserving the geometric structure. The S-TM-S bridging bond emerges as the most stable configuration.

Optimization of Multiplex-PCR Technique To Determine Azf Deletions in infertility Male Patients.

Background: To optimize the multiplex polymerase chain reaction (M-PCR) technique to diagnose microdeletions of azoospermia factors (AZF) on the Y chromosome and initially apply the technique to diagnose male patients with sperm density less than 5×10 million sperm/mL was assigned to do a test to check for AZF microdeletions on the Y chromosome.

Methods: Based on the positive control samples which belong to male subjects who have had 2 healthy children without any assisted reproductive technologies, the M-PCR method was developed to detect simultaneously and accurately AZF microdeletions on 32 male patients with sperm densities below 5×10 million sperm/mL of semen at the Department of Biology and Medical Genetics - Vietnam Military Medical University.

Results: Successful optimization of the M-PCR technique including 7 reactions arranged according to each AZFabc region using 24 STS/gene on the Y chromosome.

Different Impacts of Traffic-Related Air Pollution on Early-Onset and Late-Onset Asthma.

Background: Early-onset asthma (EOA) and late-onset asthma (LOA) are two distinct phenotypes. Air pollution has been associated with an increase in poorer asthma outcomes. The objective of this study was to examine the effects of traffic-related air pollution (TRAP) on asthma outcomes in EOA and LOA patients.

Gypenosides Production and Spermatogenesis Recovery Potentials of Extracts from Cell Suspension Cultures of .

Background: , also called Giao-co-lam, is a traditional Vietnamese herb, also known as the "Herb of Immortality", that grows throughout Asian countries and is used for the treatment of hematuria, edema in the pharynx and neck, tumors, and trauma.

Methods: In this study, we investigated the effects of culture conditions on cell growth and total gypenoside accumulation in the GP suspension cells. Cells were cultured on Murashige and Skoog (MS) medium supplemented with 2.

Endoscopic and Histopathological Characteristics of Gastrointestinal Lymphoma: A Multicentric Study.

: Extranodal non-Hodgkin lymphoma (NHL) is more prevalent in the gastrointestinal (GI) tract than in other sites. This study aimed to determine the endoscopic characteristics of primary gastrointestinal non-Hodgkin lymphomas. : We investigated 140 patients from three tertiary referral hospitals with primary malignant lymphoma of the gastrointestinal tract.

Stem cell therapies for periodontal tissue regeneration: A meta-analysis of clinical trials.

Objective: Stem cell therapy in periodontal tissue regeneration has reported optimistic regenerative results; evidence supporting its superiority over conventional methods is still ambiguous. Therefore, this meta-analysis aims to evaluate the therapeutic effects of stem cells in human periodontal regeneration.

Design: A literature search was conducted to retrieve relevant articles on periodontal regeneration in stem cell therapy.

Escalating Catalytic Activity for Hydrogen Evolution Reaction on MoSe@Graphene Functionalization.

Developing highly efficient and durable hydrogen evolution reaction (HER) electrocatalysts is crucial for addressing the energy and environmental challenges. Among the 2D-layered chalcogenides, MoSe possesses superior features for HER catalysis. The attractions and high surface energy, however, stack the MoSe layers, resulting in a loss of edge active catalytic sites.

Osteochondral Regeneration Ability of Uncultured Bone Marrow Mononuclear Cells and Platelet-Rich Fibrin Scaffold.

Objectives: Platelet-rich fibrin (PRF) and bone marrow mononuclear cells are potential scaffolds and cell sources for osteochondral regeneration. The main aim of this paper is to examine the effects of PRF scaffolds and autologous uncultured bone marrow mononuclear cells on osteochondral regeneration in rabbit knees.

Materials And Methods: Three different types of PRF scaffolds were generated from peripheral blood (Ch-PRF and L-PRF) and bone marrow combined with uncultured bone marrow mononuclear cells (BMM-PRF).

Upgrading nirmatrelvir to inhibit SARS-CoV-2 Mpro via DeepFrag and free energy calculations.

The first oral drug for the treatment of COVID-19, Paxlovid, has been authorized; however, nirmatrelvir, a major component of the drug, is reported to be associated with some side effects. Moreover, the appearance of many novel variants raises concerns about drug resistance, and designing new potent inhibitors to prevent viral replication is thus urgent. In this context, using a hybrid approach combining machine learning (ML) and free energy simulations, 6 compounds obtained by modifying nirmatrelvir were proposed to bind strongly to SARS-CoV-2 Mpro.

Protective Effect of Gaertn. Extract on Heat Stress-Induced Spermatogenesis Complications in Murine Model.

Gaertn. is a precious herb used in traditional medicine systems in Asian countries for various health benefits. This study investigated the potential protective effects of extract on reproductive health under heat stress conditions in male mice.

Investigating the association between alcohol intake and male reproductive function: A current meta-analysis.

Background: Alcohol use and alcohol-related health problems are on the rise in developing countries. This meta-analysis was conducted to determine the effects of alcohol consumption on human male reproductive function through semen parameters, antioxidants in semen, sperm DNA fragmentation, and sex hormones.

Methods: Studies regarding the effects of alcohol consumption on male reproductive function were searched on databases.

Higher Particulate Matter Deposition in Alveolar Region Could Accelerate Body Fat Accumulation in Obstructive Sleep Apnea.

We conducted a cross-sectional study to investigate associations of particulate matter (PM) of less than 2.5 μm in aerodynamic diameter (PM) and PM deposition with nocturnal changes in body composition in obstructive sleep apnea (OSA) patients. A bioelectric impedance analysis was used to measure the pre- and postsleep body composition of 185 OSA patients.

Rotary bi-layer ring-shaped metamaterials for reconfiguration absorbers.

A reconfigurable metamaterial absorber (MA) in the microwave region is numerically and experimentally demonstrated based on a multi-layered metamaterial. The proposed structure can be mechanically switched between two different configurations to obtain designated absorption behaviors. By rotating the upper ring layer by multiples of 90 deg, two separated absorption modes of the MA are created.

Rotary bi-layer ring-shaped metamaterials for reconfiguration absorbers: publisher's note.

This publisher's note corrects errors in Appl. Opt.61, 9078 (2022)APOPAI0003-693510.

Correction: Characterizing the ligand-binding affinity toward SARS-CoV-2 Mpro physics- and knowledge-based approaches.

Correction for 'Characterizing the ligand-binding affinity toward SARS-CoV-2 Mpro physics- and knowledge-based approaches' by Son Tung Ngo , , 2022, https://doi.org/10.1039/d2cp04476e.

Characterizing the ligand-binding affinity toward SARS-CoV-2 Mpro physics- and knowledge-based approaches.

Computational approaches, including physics- and knowledge-based methods, have commonly been used to determine the ligand-binding affinity toward SARS-CoV-2 main protease (Mpro or 3CLpro). Strong binding ligands can thus be suggested as potential inhibitors for blocking the biological activity of the protease. In this context, this paper aims to provide a short review of computational approaches that have recently been applied in the search for inhibitor candidates of Mpro.

Density Functional Study of Size-Dependent Hydrogen Adsorption on Ag Cr ( = 1-12) Clusters.

Increasing interest has been paid for hydrogen adsorption on atomically controlled nanoalloys due to their potential applications in catalytic processes and energy storage. In this work, we investigate the interaction of H with small-sized Ag Cr ( = 1-12) using density functional theory calculations. It is found that the cluster structures are preserved during the adsorption of H either molecularly or dissociatively.