Neuroprotective effects of halofuginone in rat's sciatic nerve injury.

Objective: The object of the present study was to investigate the neuroprotective effects of halofuginone-with its antifibrotic and anti-inflammatory effects-on peripheral nerve injuries frequently encountered in daily life, at the functional, pathological, and cellular levels through the use of electron microscopy.

Methods: Forty Wistar rats were distributed into 4 groups. Group 1 (sham group) consisted of rats with only exposed nerves; group 2 (control group) consisted of traumatized rats; group 3 (MP group) consisted of rats receiving methylprednisolone treatment after trauma; group 4 (halofuginone group) consisted of rats receiving halofuginone treatment after trauma.

Relationship Between Defect Volume and Comorbid Pathologies in Patients Undergoing Surgery for Myelomeningocele.

Aim: To determine sac volume based on radiological examinations in patients undergoing surgery for myelomeningocele (MMC) and to investigate the relationship of sac volume with hydrocephalus and Chiari malformation type 2 (CM) with a view to determining the optimum length of follow-up and recommend a treatment plan.

Material And Methods: The present study involved the retrospective review of radiologic examinations and medical files of 81 patients who underwent surgery for myelomeningocele between 2015 and 2022 in the neurosurgery clinic of Ankara Training and Research Hospital. Then, MMC sac volumes were measured and the statistical relationship of these measurements with the Evans Index, progressive enlargement of the ventricles after sac repair and CM was investigated.

Factors Affecting Resorption Following Cranioplasty with an Autologous Bone Graft.

Aim: To evaluate the relationship between the surgical techniques, the waiting time for surgery, postoperative distance between the graft-bone margin and the percentage of bone resorption, we analyzed patients who underwent cranioplasty. Cranioplasty is a necessary surgery to preserve brain tissue and provide an appropriate microenvironment.

Material And Methods: In this study, patients who underwent autologous bone grafting after decompressive craniectomy by the Neurosurgery Clinic of University of Health Sciences Ankara Training and Research Hospital between 2018 and 2021 were examined.

Mucosa-Associated Lymphoid Tissue Lymphoma With Lymphomeningothelial Lesion of the Dura.

Mucosa-associated lymphoid tissue (MALT) was first described as low-grade lymphoma associated with the stomach mucosa. Although the stomach and ocular adnexa are the most common localizations of MALT lymphoma, it has also been described in many other organs, including the head and neck, lungs, thyroid, breast, bladder, saliva glands, conjunctiva, and tear glands. MALT lymphoma originating from the dura is rare.

The diagnostic value of cranial MRI findings in idiopathic intracranial hypertension: evaluating radiological parameters associated with intracranial pressure.

Background: Idiopathic intracranial hypertension (IIH) is a disease that can result in blindness if there is a delay in diagnosis. Although it is stated that cranial imaging should be normal among the diagnostic criteria, we know that some radiological parameters can be used for the pre-diagnosis of IIH.

Purpose: To determine the predictive value of radiological parameters for the diagnosis of IIH with cranial magnetic resonance imaging (MRI).

The relationship between pain and herniation radiology in giant lumbar disc herniation causing severe sciatica: 15 cases.

Objective: To evaluate conservative treatment of giant lumbar disc herniation in patients with extreme pain and to assess temporal changes in pain levels and radiological findings with short-term follow-up.

Methods: A total of 15 patients with severe pain (as measured by visual analog scale [VAS]) due to giant lumbar disc herniation and without neurological deficits were included. All patients received conservative treatment and were followed weekly for pain and medication assessment.

Decompressive Hemicraniectomy for Malignant Middle Cerebral Artery Infarct.

Aim: Decompressive hemicraniectomy for a malignant middle cerebral artery infarct can be a life-saving surgical treatment. We aimed to investigate the surgical treatment results in cases that underwent decompressive hemicraniectomy for a malignant middle cerebral artery infarct in this study.

Material And Methods: The clinical condition, radiological findings and surgical treatment results of 42 cases that underwent decompressive hemicraniectomy for a malignant middle cerebral artery infarct were retrospectively evaluated in this study.