Publications by authors named "Tumuluri K"

Purpose: Microcystic adnexal carcinoma (MAC) is a locally aggressive adnexal carcinoma of the head and neck, which has a high tendency for recurrence. MAC rarely has distant metastasis, with only one previously reported case originating from the periorbital region. We present a patient with periorbital MAC with distant metastasis and a review of all reported patients with metastatic disease.

View Article and Find Full Text PDF

Our aim is to present two cases of infantile sinonasal tract myxoma with orbital involvement and conduct a comprehensive literature review of the topic. We aim to provide a summary of the presentation of infantile sinonasal tract myxomas to effectively aid clinicians in considering this rare entity as a potential diagnosis. We present a case series and a retrospective review of the published literature in the English language.

View Article and Find Full Text PDF

Purpose: Blepharocheilodontic (BCD) syndrome is a rare condition with eyelid ectropion, euryblepharon, lagophthalmos, congenital cleft lip/palate, and oligodontia. BCD syndrome is an autosomal dominant inherited disorder and has multiple associations with systemic diseases. We present three new cases of BCD syndrome and a literature review of the periocular manifestations of BCD and their management.

View Article and Find Full Text PDF
Article Synopsis
  • This study evaluated radiological features and clinical outcomes of four patients with odontogenic orbital cellulitis, focusing on causative organisms, clinical signs, and visual results.
  • Patients had a mean age of 43 years and all presented with severe symptoms, including various levels of visual impairment; Streptococcus milleri and Streptococcus constellatus were primarily responsible for the infections.
  • The findings indicated significant risks of vision loss, with two patients ending up blind, and one requiring an orbital exenteration due to severe complications, emphasizing the condition's seriousness.
View Article and Find Full Text PDF

Purpose: The purpose of this study was to provide Australian data on the clinical and radiological features and outcomes in patients with orbital plasmacytomas.

Methods: Multicentre retrospective review of orbital plasmacytoma and orbital involvement in multiple myeloma (MM) from 2005 to 2022 in Australia.

Results: Twenty-one participants were identified.

View Article and Find Full Text PDF
Article Synopsis
  • Molluscum contagiosum (MC) is a common, non-threatening viral skin infection primarily affecting children and certain adults, including those with weakened immune systems.
  • The article discusses two rare pediatric cases of giant periorbital MC lesions accompanied by preseptal cellulitis.
  • In the first case, a 9-month-old boy underwent surgical excision after a diagnosis of MC, while the second case involved an 18-month-old girl who was treated with antibiotics and surgery.
View Article and Find Full Text PDF

Necrobiotic xanthogranuloma (NXG) is a rare systemic disease, that commonly manifests with orbital and ocular adnexal involvement, presenting with periocular yellow papules and plaques that may ulcerate. Periorbital skin lesions are a hallmark of the disease, and in their absence the diagnosis may be delayed, preventing prompt systemic evaluation and appropriate treatment of this condition. We report a unique case of a 58-year-old female patient with NXG that presented with severe bilateral necrotizing scleritis, left orbital mass and no cutaneous manifestations of NXG.

View Article and Find Full Text PDF
Article Synopsis
  • Pilomatrixoma is a benign tumor that can occur around the eyes but is often misdiagnosed; it's mostly found in the upper eyelid and eyebrow area.
  • A study from 2010 to 2023 reviewed 77 cases, revealing a slight female predominance and most cases occurring in young people, with no malignant transformation noted.
  • Complete surgical removal is usually effective, and while two recurrences were reported, they're rare, highlighting the importance for doctors to recognize this condition in younger patients.
View Article and Find Full Text PDF

The copper/nickel-metal on commercial H-Beta zeolite supports was synthesized with different wt % (Ni) of 5, 10, 15, and 20, and was used in the cyclohexene epoxidation process. The synthesized catalyst has been used in a continuous reactor for the cyclohexene epoxidation process, with mild conditions and HO as an oxidant. The catalytic performance was ascertained by adjusting parameters such as the temperature, pressure, WHSV, reaction time, and solvents.

View Article and Find Full Text PDF

Merkel cell carcinoma (MCC) is an uncommon and aggressive skin cancer of neuroendocrine origin. The tumor usually presents with a locoregional spread and most frequently metastasizes to the skin, liver, bone, lung, and brain. Despite the orbit being a relatively common site of metastases, it has rarely been reported in patients with MCC.

View Article and Find Full Text PDF
Article Synopsis
  • Juvenile xanthogranuloma (JXG) is a rare pediatric skin condition that usually appears as a single nodule, and orbital JXG is an even rarer form that affects the eye area.
  • A review of three cases of orbital JXG revealed a diverse range of symptoms and no clear consensus on the best treatment, though steroids are commonly used.
  • The classification of JXG is evolving, and it remains uncertain how orbital JXG fits into this classification, particularly regarding its biological mechanisms compared to cutaneous JXG.
View Article and Find Full Text PDF

Purpose: Corneal neurotization is an emerging technique that offers potential for visual rehabilitation in neurotrophic keratopathy. This study reports on a multicenter experience and outcomes for both direct and indirect methods of corneal neurotization.

Methods: Retrospective case series.

View Article and Find Full Text PDF
Article Synopsis
  • Orbital Apex Syndrome (OAS) is a severe complication of Herpes Zoster Ophthalmicus (HZO) that can lead to serious vision loss, and this study examines four cases to improve recognition and treatment.
  • Imaging results from CT and MRI showed changes in the extraocular muscles and surrounding areas, indicating significant inflammation around the eye.
  • While all patients were treated with steroids and antivirals, there is still no established standard for the dosage and duration of these treatments, resulting in different visual outcomes for the patients.
View Article and Find Full Text PDF

Isolated orbital mucocele without connection between the mass and paranasal sinuses is extremely rare and poorly understood. Literature review of these cases are very few and present more anteriorly in the orbit. Here, the authors present a 33-year-old female with an isolated left orbital apex mucocele without direct communication with the adjacent paranasal sinuses and other vital orbital structures.

View Article and Find Full Text PDF

Purpose: Globe-sparing excision for periocular basal cell carcinoma (BCC) with orbital invasion has evident benefits, but the ensuing morbidity and characteristics of recurrence are not well elucidated. This study aims to describe the extent of visual morbidity following globe-sparing excision, and the clinicoradiological characteristics of tumor recurrence.

Methods: Multicentre retrospective case series.

View Article and Find Full Text PDF
Article Synopsis
  • Aneurysmal bone cyst (ABC) of the orbit is a rare tumor primarily affecting children, leading to potential vision loss and facial disfigurement; the review highlights treatment advancements and genetic factors.
  • The youngest documented case involved a 17-month-old girl with a specific gene fusion, and a literature search identified 32 cases, showcasing diverse symptoms like pain and vision issues.
  • Treatment options include surgery, embolization, and RANKL inhibitors, but there is a risk of recurrence within two years; genetic testing may enhance diagnosis and improve treatment outcomes.
View Article and Find Full Text PDF

Purpose: The aim of this study is to report two cases of paediatric Yolk sac tumours (YST) of the orbit and sinonasal tract, with a major review on the subject.

Methods: Two case reports along with a comprehensive retrospective literature review of all English language publications between 1974 and 2021 is presented. Literature review examined the demographics, clinical presentation and diagnostic and prognostic factors of extragonadal YSTs of the orbit and sinonasal tract.

View Article and Find Full Text PDF

Purpose: Neurotrophic keratopathy is a degenerative disease characterized by damage to the corneal nerves leading to corneal hypoesthesia and anaesthesia. The resultant progressive visual deterioration is refractory to existing conventional treatment options. Corneal neurotization is a novel and effective surgical procedure that directly targets the underlying pathology of nerve loss by stimulating new corneal nerve growth.

View Article and Find Full Text PDF

The hydrogel scleral buckle is a hydrophilic implant that is characterized by progressive expansion and can present with secondary orbital changes. The authors present a unique case of hydrogel-induced erosion of the orbital roof into the frontal sinus, with formation of a sino-orbital communication that resulted in frontal sinusitis and adjacent cerebritis. The hydrogel material is radiologically characterized as a fluid-filled hypertense T2 mass with rim enhancement and peripheral calcification.

View Article and Find Full Text PDF

Background: There is a growing effort to develop implantable bionics for restoring eye closure in paralytic lagophthalmos. Knowledge of the natural eyelid attachments is important for active implants that mobilise these attachments or replace them with a sling. Whitnall's tubercle (WT) is traditionally used to identify lateral canthal attachments; however, it is not always present.

View Article and Find Full Text PDF
Article Synopsis
  • The supplementary data relates to a study on a novel suprachoroidal visual prosthesis implanted in sheep, assessing surgical safety, device stability, and biocompatibility.
  • Nine sheep underwent surgery with an electrically inactive retinal stimulator, monitored for up to 100 days through various imaging techniques.
  • The collected data, including images and histological analysis, serves as a reference for future research, particularly concerning active retinal stimulators and the suitability of Dorper sheep as research models.
View Article and Find Full Text PDF

Severe visual impairment can result from retinal degenerative diseases such as retinitis pigmentosa, which lead to photoreceptor cell death. These pathologies result in extensive neural and glial remodelling, with survival of excitable retinal neurons that can be electrically stimulated to elicit visual percepts and restore a form of useful vision. The Phoenix Bionic Eye is a fully implantable visual prosthesis, designed to stimulate the retina from the suprachoroidal space.

View Article and Find Full Text PDF