Publications by authors named "Tumalisi Abudureheman"
Front Immunol
September 2024
Article Synopsis
- - This study investigates the use of interleukin-1 beta (IL-1β) as a molecular adjuvant to boost the immune response in chickens immunized with genetically engineered anticoccidial vaccine strains to combat coccidiosis.
- - Chickens immunized with the transgenic strain expressing chIL-1β showed a significant reduction in oocyst output after being challenged, indicating enhanced immunogenicity compared to those immunized with the wild type strain.
- - Despite no differences in overall health indicators like body weight or lesion scores, the elevated levels of immunogenicity markers suggest that the chIL-1β has potential for creating more effective live-oocyst-based vaccines without increasing harmful effects. *
