Publications by authors named "Tulio P Navarro"

Arterial stiffening is associated with adverse cardiovascular patient outcomes; stiffness may also be associated with postsurgical events and has been suggested to be a fundamental mechanism in the pathogenesis of aortic aneurysms. Although open repair of aneurysms decreases aortic stiffness, implantation of a rigid endograft is associated with increased aortic stiffness after endovascular aneurysm repair (EVAR). This review provides an overview of aortic wall physiology and the contemporary understanding of aortic stiffness and its implications for patients undergoing abdominal aortic aneurysm repair.

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Due to the anatomical complexity of the aortic arch for the development of stent-grafts for total repair, this region remains without a validated and routinely used endovascular option. In this work, a modular stent-graft for aneurysms that covers all aortic arch zones, proposed by us and previously structurally evaluated, was evaluated from the point of view of haemodynamics using fluid-structural numerical simulations. Blood was assumed to be non-Newtonian shear-thinning using the Carreau model, and the arterial wall was assumed to be anisotropic hyperelastic using the Holzapfel model.

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The diabetic foot interacts with anatomical, vascular, and neurological factors that challenge clinical practice. This study aimed to compile the primary scientific evidence based on a review of the main guidelines, in addition to articles published on the Embase, Lilacs, and PubMed platforms. The European Society of Cardiology system was used to develop recommendation classes and levels of evidence.

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The development of stent-grafts for the total repair of aneurysms in the aortic arch is still a technical challenge due mainly to the anatomical complexity of this region. Research performed here structurally evaluated a modular branched stent-graft for aneurysms encompassing all zones of the aortic arch by means of numerical simulations using fluid-structure interaction. The geometric domain obtained by means of computed tomography was subjected to physiological boundary conditions.

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  • The study investigates the effectiveness of sclerotherapy using 1% polidocanol foam for treating low-flow vascular malformations, aiming to identify factors influencing treatment success.
  • Conducted between December 2016 and November 2018, the research involved 40 lesions in 38 patients, mainly consisting of venous malformations, with common symptoms including deformity, pain, and functional limitations.
  • Results indicated that larger lesions (over 10 cm) correlated with higher psychosocial issues and that deep lesions were linked to more functional limitations, suggesting a need for careful patient selection for sclerotherapy.
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  • Pressure injuries (PIs) are a significant issue in healthcare, particularly in ICUs, where they can severely affect patient quality of life and increase care costs despite being largely preventable.
  • The study aimed to create a simplified version of the Braden scale by removing two subjective subscores (Nutrition and Sensory Perception) to improve accuracy in risk assessment for nursing teams.
  • The results indicated that both the original and simplified Braden scales effectively differentiate between patients with and without PIs, with minimal impact on classification performance, thereby facilitating more efficient and objective risk classification in clinical practice.
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  • - The study examines the effectiveness of the pedal acceleration time (PAT) as an alternative method to the ankle-brachial index (ABI) for evaluating limb blood flow in diabetic patients with chronic limb-threatening ischemia (CLTI), particularly when traditional ABI measurements are challenging.
  • - A cross-sectional study involved 141 patients (both diabetic and nondiabetic) to assess how well PAT predicts lower-limb ischemia by measuring its accuracy against ABI categories and Wound, Ischemia, and foot Infection (WIfI) scores.
  • - Results indicated that PAT demonstrated high accuracy in correlating with ABI levels and WIfI stages: 85% for ABI < 0.8 in nondiabetic patients, and
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Introduction: perioperative risk assessment is essential to mitigate surgical complications, which suggests individual and collective interest since the number of surgical procedures in Brazil has been expanding steadily. The aim of this study was to summarize and detail the main calculators, indexes and scores regarding perioperative pulmonary, renal, hepatobiliary, hematological and surgical site infection risks for general non-cardiac surgeries, which are dispersed in the literature.

Method: a narrative review was performed based on manuscripts in English and Portuguese found in the electronic databases Pubmed/MEDLINE and EMBASE.

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  • The intermesenteric artery (IA) connects the superior mesenteric artery (SMA) and inferior mesenteric artery (IMA) and is present in about 9-18% of cadaver dissections, with this study being the first to analyze it using in vivo imaging.
  • A total of 150 abdominal CT angiographies were examined for the IA's characteristics, focusing on its presence, origin, pathway, insertion point, and diameter, measuring various arterial diameters in male and female patients.
  • Results showed the IA was present in a significant number of both sexes, with no size difference in the IA between males and females, but larger diameters observed in the SMA compared to the IMA, indicating that the IA commonly
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The number of surgical procedures in the world is large and in Brazil it has been expressing a growth trend higher than the population growth. In this context, perioperative risk assessment safeguards the optimization of the outcomes sought by the procedures. For this evaluation, anamnesis and physical examination constitute an irreplaceable initial stage which may or may not be followed by complementary exams, interventions for clinical stabilization and application of risk estimation tools.

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Background: Chronic kidney disease is a major public health problem. Hemodialysis is the most common renal replacement therapy. Arteriovenous fistulas (AVF) are a possible access option, but early failure rates remain high.

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Objectives: This study aimed to correlate a higher Pelvic-Trochanteric Index (PTI) with an increased varus of the femoral neck with greater trochanteric pain syndrome (GTPS). The secondary objective was to check whether the pelvic width changes with age.

Methods: A prospective study was conducted to compare female patients diagnosed with GTPS (case group) with asymptomatic female participants (control group) from March 2011 to June 2017.

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  • The study aimed to evaluate the effectiveness of Transcutaneous Electric Nerve Stimulation (TENS) in reducing rest pain for patients suffering from chronic limb-threatening ischemia.
  • A total of 23 patients were randomly assigned to receive either TENS or a sham intervention, with results measured using pain intensity scales.
  • Both groups reported a significant decrease in pain levels, but there was no meaningful difference in pain relief between the TENS and sham treatments.
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Objective: Arterial stiffness indices predict cardiovascular outcomes in patients with coronary or kidney disease; however, there is little data on the prognostic value of arterial stiffness in patients with advanced peripheral arterial disease. We determined whether arterial stiffness indices predict the outcomes of major amputation or death in patients with chronic limb-threatening ischemia (CLTI).

Methods: Arterial stiffness was prospectively measured using brachial oscillometry in patients with CLTI.

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Gastric carcinoma (GC) locoregional recurrence may occur even in cases where the tumor has been completely resected, possibly due to lymph node (LN) micrometastases. It is estimated that in 10% to 30% of cases, LN micrometastases are not detected by a conventional method for histological assessment of LN metastases with hematoxylin-eosin (HE). A cross-sectional study assessed 51 patients with GC by histological evaluation of the LN micrometastases through LN multi sectioning associated with immunohistochemistry analysis with monoclonal antibodies AE1 and AE3.

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Objective: Lower extremity varicose veins have a high prevalence and can be associated with significant morbidity in their more advanced presentations; overweight patients tend to present with more severe clinical symptoms and conventional surgical treatment remains challenging. Although the advent of ultrasound-guided foam sclerotherapy (UGFS) increased the treatment options for these patients, the need for elastic compression after UGFS remains controversial.

Methods: Overweight patients with lower extremity varicose veins secondary to great saphenous vein reflux were treated with UGFS and then randomized to use or no use of a 3-week treatment of elastic compression stockings.

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Background: There is currently a worldwide effort to increase the options for autogenous hemodialysis access.

Objectives: To evaluate patency and complications of brachial vein transposition compared to other autogenous hemodialysis accesses.

Methods: A retrospective evaluation of 43 patients and 45 procedures.

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Background: Arterial stiffness analysis has been done to classify cardiovascular risk. The aim of this article is to analyze whether the group of patients with chronic limb-threatening ischemia (CLTI) has higher arterial stiffness indices than controls. The secondary objectives are to assess whether patients with advanced stages of Wound, Ischemia, and foot Infection (WIfI) classification have high levels of arterial stiffness, through multiple linear regressions to analyze whether the ankle-brachial index (ABI) and other variables are predictive of arterial stiffness.

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Objectives: We describe the preliminary results of thoracic endovascular aortic repair (TEVAR) in a group of patients with ascending aortic disease from the Global Registry for Endovascular Aortic Treatment (GREAT).

Methods: We identified TEVAR performed for diseases truly originating from the ascending aorta. Between July 2011 and May 2015, 5014 patients were enrolled; six (0.

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  • Foot ulcers in diabetic patients can lead to serious health issues, including amputations and increased mortality rates.
  • Researchers conducted a study on 78 patients with infected foot ulcers who underwent major lower limb amputations to identify risk factors related to mortality.
  • Key findings indicated that high serum creatinine levels and transfemoral amputations significantly increased the risk of death in these patients.
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Objective: The disease of the aortic arch is traditionally approached by open surgical repair requiring cardiopulmonary bypass and circulatory arrest. This study performed a retrospective analysis comparing outcomes through primary hybrid patients submitted to aortic arch surgery without cardiopulmonary bypass with patients submitted to conventional open surgery.

Methods: 25 patients submitted to the aortic arch surgery were selected in the period 2003-2012 at the Madre Teresa Hospital in the city of Belo Horizonte, Brazil; 13 of these underwent hybrid technique without cardiopulmonary bypass and 12 underwent conventional open surgery.

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Objectives Major and minor amputations are associated with significant rates of mortality. However, little is known about the impact of unplanned redo-amputation during the same hospitalization on outcomes. The objectives of this study were to identify the risk factors associated with in-hospital mortality after both major and minor amputations as well as the results of unplanned redo-amputation on outcome.

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Extracranial cerebrovascular disease is one of the most important causes of death and disability worldwide and its treatment is based on clinical and surgical strategies, the latter being performed by conventional or endovascular techniques. The management of stenosis of the carotid bifurcation is mainly aimed at preventing stroke and has been the subject of extensive investigation. The role of clinical treatment has been re-emphasized, but carotid endarterectomy remains the first-line treatment for symptomatic patients with 50% to 99% stenosis and for asymptomatic patients with 60% to 99% stenosis.

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