Publications by authors named "Tulika Nirmolia"

Article Synopsis
  • A comprehensive entomological survey in Alipurduar District, West Bengal, conducted from 2018 to 2020 and again in 2022, focused on identifying mosquito species linked to reported malaria cases across various health centers and villages.
  • Researchers employed hand-collection methods and utilized both morphological and molecular techniques, including sequencing of the mitochondrial cytochrome c oxidase gene (CO1), to accurately identify mosquito species and assess their potential as malaria vectors.
  • The study identified several important mosquito species, confirming the first occurrences of certain types in West Bengal and highlighting significant human blood meal positivity, which indicates their role in malaria transmission within the region.
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, a Gram-negative intracellular bacterium, naturally infects many arthropods, including mosquito vectors responsible for the spread of arboviral diseases such as Zika, chikungunya, and dengue fever. Certain strains are involved in inhibiting arbovirus replication in mosquitoes, and this phenomenon is currently being studied to combat disease vectors. A study was conducted in four states in north-eastern India to investigate the presence of natural infection in wild-caught and mosquitoes, the established vectors of dengue.

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Background: With the reports of indigenous cases of dengue and chikungunya in the forest-covered rural tribal malaria-endemic villages of Dhalai District, Tripura, India, an exploratory study was undertaken to identify the vector breeding sites.

Methods: From June 2021 to August 2022, mosquito larvae were collected from both natural and artificial sources in the villages, house premises, and their nearby forested areas outside of the houses. Other than morphological characterisation, species were confirmed by polymerase chain reaction targeting both nuclear (ITS2) and mitochondrial genes (COI) followed by bidirectional Sanger sequencing.

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Article Synopsis
  • Northeast India has high malaria endemic zones, making it crucial to study the genetic diversity of malaria parasites to understand drug resistance and its implications.* -
  • This study analyzed archived blood samples from 2006 in North Lakhimpur, Assam, using specific genomic markers, revealing significant allelic diversity and multiple genotypes.* -
  • Findings indicate persistent high genetic diversity in malaria strains from Northeast India, which poses challenges for vaccine development, especially since artemisinin replaced chloroquine for treatment.*
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Background: Malaria continues to be a major public health problem in the Northeastern part of India despite the implementation of vector control measures and changes in drug policies. To develop successful vaccines against malaria, it is important to assess the diversity of vaccine candidate antigens in field isolates. This study was done to assess the diversity of Plasmodium falciparum AMA-1 vaccine candidate antigen in a malaria-endemic region of Tripura in Northeast India and compare it with previously reported global isolates with a view to assess the feasibility of developing a universal vaccine based on this antigen.

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With India aiming to achieve malaria elimination by 2030, several strategies have been put in place. With that aim, mass surveillance is now being conducted in some malaria-endemic pockets. As dry season mass surveillance has been shown to have its importance in targeting the reservoir, a study was undertaken to assess the parasite load by a sensitive molecular method during one of the mass surveys conducted in the dry winter period.

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Cancer is an important public health burden in India and around the Globe. Incident cases of cancer are reported continuously, and trends in incidence rates vary among five yearly age group. In India National census is carried out after every 10 years since 1951, the latest census is carried out in 2011.

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Downs syndrome (DS) occurs due to an extra copy of chromosome 21. About 3% of cases of Downs syndrome occur due to Robertsonian translocation, most commonly t (14; 21), other types of translocations are very rare cause of the syndrome. A 10-year-old patient with mental retardation was admitted following road traffic accident.

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Background: Cancer is becoming the most important public health burden around the globe. As per the GLOBOCAN 2008 estimates, about 12.7 million cancer cases and 7.

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The name Paragonimus westermani (Kerbert, 1878) is commonly applied to members of a species complex that includes the well-known Asian lung fluke of medical and veterinary importance. Unambiguous molecular and morphological evidence showing the presence of a member of the complex in India has recently been published. In the present study we report the occurrence of 2 more members of the P.

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