Antioxidant effect of Legalon(r) SIL in ischemia-reperfusion injury of rat skeletal muscle.

Purpose: To evaluated the potential antioxidant agent Legalon (r) SIL (silibinin-C-2',3-bis(hydrogensuccinat)) in the skeletal muscle of rats.

Methods: IRI was achieved via tourniquet application in Wistar-albino rats. Experimental groups were chosen as (i) sham control, (ii) IRI (3+2 h), (iii) IRI and Legalon (r) SIL-50 (50 mg/kg/i.

The short- and long- term effects of estrogen deficiency on apoptosis in musculoskeletal tissues: an experimental animal model study.

Background: Estrogen is the major sex steroid affecting the growth, remodeling, and homeostasis of the female skeleton. Estrogen loss in postmenopausal women leads to osteoporosis. The aim of this study was to evaluate the early and long- term effects of estrogen loss on bones, tendons, muscles, and menisci in ovariectomized rats.

Effects of silibinin and ethanol on skeletal muscle ischemia-reperfusion injury.

Purpose: To investigate the potential beneficial effect of silibinin in ischemia-reperfusion injury (IRI) of skeletal muscle.

Methods: Under urethane anesthesia, four experimental groups were established in Balb/c mice: I) Sham-control, II) IRI (Tourniquet-induced) (2+1 h), III) IRI+ethanol (10%), and IV) IRI+silibinin (50 mg/kg/IP). The viability of muscle (left) was evaluated by the triphenyltetrazolium chloride dye method and calculated as the percentage of the contralateral control muscle (right).

Gouty arthritis at interphalangeal joint of foot after sildenafil use: A case report.

Introduction: Interphalangeal joint of foot is a very unusual location for gouty arthritis and sildenafil use may cause this phenomenon.

Presentation Of Case: A 58-year-old hypertensive man was admitted to hospital with pain and swelling over interphalengeal joint of his right great toe. His health history included the use of diuretics for a long time and his last gout attack was two years ago at first metatarsophalengeal joint of right foot.

Deformity correction by Ilizarov distraction osteogenesis after distal radius physeal arrest.

Objective: The aim of this study was to evaluate the results of osteotomy and distraction osteogenesis using Ilizarov circular external fixator to treat radial shortening and severe wrist deformity due to neglected post-traumatic distal radius physeal arrest.

Methods: The study retrospectively reviewed 4 patients (4 males; average age: 16 years; range: 14 to 19 years) who underwent osteotomy and distraction osteogenesis to treat radial shortening and severe wrist deformity due to neglected distal radius physeal arrest. Mean interval between trauma and surgical intervention was 8 (range: 4 to 12) years and mean follow-up time was 83 (range: 40 to 126) months.

Relationship between meniscal tears and tibial slope on the tibial plateau.

Objective: The geometry of the tibial plateau has a direct influence on the translation and the screw home biomechanics of the tibiofemoral joint. Little information on the relationship between the tibial slope and meniscal lesions is available. The objective of this retrospective study was to examine the effect of the tibial slope on the medial and lateral meniscus lesions in patients with intact ACLs.

Neural fibrolipoma of the digital nerve: a case report.

A 32-year-old woman underwent microsurgical resection of a neural fibrolipoma of the digital nerve of the ring finger. At the 6-month follow-up, the patient had good recovery, no recurrence, and preservation of neural function. Caution should be exercised while planning microsurgical dissection on soft-tissue masses of fingers and hands.

Unicameral bone cyst of the lunate in an adult: case report.

We report a case of a symptomatic unicameral (simple) bone cyst of the lunate in a 42-year- old woman. The lesion was treated with curettage and cancellous autogenous iliac bone grafting. At five years of follow-up the wrist was pain free, there were no limitations of motion, and the radiographs showed complete obliteration of the cavity.

Protective effect of zinc aspartate on long-term ischemia-reperfusion injury in rat skeletal muscle.

The present study investigated the protective effect of zinc aspartate, in connection with reactive oxygen species and nitric oxide, on long-term ischemia-reperfusion injury (IRI) in rat skeletal muscle. Following ketamine anesthesia, 24 rats were randomly assigned to four groups: groups 1 and 2, each without tourniquet application, received no drug and zinc, respectively; groups 3 and 4, each subjected to tourniquet-induced IRI (3 + 24 h), received no drug and zinc, respectively. IRI was achieved by the application of an elastic rubber band in the left hind limb of the anesthetized rats.

Modified Judet's quadricepsplasty for loss of knee flexion.

We reviewed the results of a modified Judet's quadricepsplasty in eleven patients with inability to fully flex the knee. The patients were examined at an average follow-up of 49 months (4 to 108 months). Their mean pre-operative knee flexion was 30 degrees (range 10 degrees -50 degrees ).

Upper-extremity digital amputation secondary to non-traumatic ischemia.

In an attempt to evaluate the factors that result in upper-extremity digital amputation secondary to acute non-traumatic ischemia, nine patients with digital amputations secondary to septic or non-septic emboli were evaluated retrospectively. Although some evidence was present in three patients, no primary focus of emboli could be confirmed in six cases. All patients were consulted about hand surgery > or = 7 days following the clinical suspicion of ischemia for different reasons.

A very large Schwannoma originating from the median nerve in carpal tunnel.

Schwannomas are common benign nerve tumors occurring in the peripheral nerves. A very large schwannoma of more than 5 years duration, originating from the median nerve in the carpal tunnel in a 38-year-old woman, is reported. There was a painful mass, 60 mm in length and 42 mm in diameter, on the palm without signs of sensory disturbance or atrophy on the thenar muscles.