Publications by authors named "Tugba Ocak"

Background: Information and education are recommended for patients with inflammatory arthritis including spondyloarthritis (SpA). However, there is no Turkish instrument available to measure the knowledge level of patients with SpA. The study aimed to translate the Spondyloarthritis Knowledge Questionnaire (SPAKE) into Turkish and investigate its validity and reliability.

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: Secukinumab is a monoclonal antibody against interleukin 17 approved for patients with axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), and psoriasis. Treating axSpA and PsA patients with a history of malignancy is a challenge. While initial results on the applicability of secukinumab in this patient group are positive, the number of studies on this topic remains limited.

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Patients with axial spondyloarthritis (axSpA) who receive immunosuppressive therapy are at risk of infection due to impaired immune function and immunosuppressive medication. Vaccination plays a crucial role in preventing infections in this population. However, vaccination rates and factors influencing vaccination uptake in axSpA patients still need to be adequately studied.

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Familial Mediterranean fever (FMF) is characterized by recurrent episodes of fever and serositis. Blood-based biomarkers determined in FMF patients during attack-free periods could be used to predict the risk of amyloidosis and the severity of the disease. The recently defined pan-immune-inflammation value (PIV) comprises four distinct subsets of blood cells and serves as an easily accessible and cost-effective marker.

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Objective: To determine the rate of unintentional monotherapy (UM; switching to monotherapy from combination therapy of patients' own volition) in rheumatoid arthritis patients receiving tofacitinib and to evaluate tofacitinib survival rate.

Methods: This national, multicenter study included patients' data from the TURKBIO Registry. Demographics, clinical characteristics, disease duration and activity, comorbidities, and treatments were analyzed.

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Background: Spontaneous bacterial peritonitis (SBP) is an important reason for mortality in cirrhosis. This study aimed to identify the factors associated with mortality in SBP.

Materials And Methods: A total of 69 patients with cirrhosis and 74 with SBP attacks that occurred in this group were assessed.

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Article Synopsis
  • Idiopathic granulomatous mastitis (IGM) is a rare, non-cancerous breast disease that mostly affects women ages 30 to 45, often after having a baby.
  • The study looked at 120 women with IGM to find out which treatments worked best and to see how often the disease came back after treatment.
  • About half of the women had their IGM come back after treatment, and those who had surgery first were more likely to experience this recurrence compared to those who did not.
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