Publications by authors named "Tugba Bedir-Demirdag"

Article Synopsis
  • The study examines how the COVID-19 pandemic affected the rates and types of viral respiratory infections in children under 18 years old, by analyzing medical records from January 2018 to March 2023.
  • A significant decline in these infections was noted in 2020 (38.6% drop), followed by a surge in 2021 (188% increase), indicating fluctuating patterns post-pandemic.
  • Notably, respiratory syncytial virus and influenza infections rose in frequency in the post-pandemic period, while parainfluenza virus infections showed an unusual increase during summer months, adding new insights to existing research.
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Background: It is known established that the cardiac effects of COVID-19 infection are associated with poor prognosis and high mortality rates in infected patients. The aim of this study was to evaluate the cardiac effects of COVID-19 infection in paediatric patients and identify the correlations between clinical and laboratory data and the degree of cardiac involvement.

Materials And Methods: A retrospective data analysis was conducted on 64 paediatric patients at Gazi University Department of Pediatrics who were treated as inpatients with a diagnosis of COVID-19.

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Respiratory syncytial virus (RSV) is the most common cause of lower respiratory tract infections in children. In most previously healthy infants, RSV infection is self-limited and resolves without complications. The risk of bacteremia is low in young febrile infants with RSV infection.

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Article Synopsis
  • Biologic modifying agents in pediatric patients are linked to a higher risk of developing tuberculosis (TB), prompting a study to document this in a hospital setting from 2010 to 2020.
  • A total of 72 patients treated with these agents were analyzed, finding that 9.7% tested positive for latent TB, with older patients and those receiving treatment for a longer duration being more likely to develop it.
  • Interestingly, although canakinumab is generally considered to have a lower risk for TB conversion, it was the most commonly associated agent among those who tested positive in this study.
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is the leading cause of community-acquired pneumonia and bacterial meningitis in children. Although pneumococcal conjugate vaccines (PCVs) are commonly available, invasive pneumococcal disease (IPD) still remains a life-threatening complication. Serotype 19A has high invasive potential and is capable of causing extensive and destructive lung disease.

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Rubella infections are rarely seen where immunization programmes are in place. Congenital rubella syndrome is however still observed where the vaccination programme against rubella is not administered or interrupted. We present such a case, with typical clinical anomalies including congenital cataracts, sensorineural hearing loss and bone lesions.

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Studies have demonstrated an association between CHD and neurodevelopmental delay. This delay is associated with many factors like reduced blood flow and oxygen, cardiac catheterisations, and genetic factors. Apo E gene polymorphism is one of these genetic factors.

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Human Rhinovirus (HRV) is one of the most common pathogens causing acute respiratory tract infections in infants and children. Several reports suggest that HRV has the potential to cause chronic infection after an acute viral infection in an immunosuppressed patient. Although chronic HRV infection has been reported in lung transplant recipients, patients with hypogammaglobulinemia and cystic fibrosis, the duration and severity of HRV infection remain unclear.

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Objectives: Graft-versus-host disease is still one of the most important complications after hematopoietic stem cell transplantation. The risk factors remain unclear, with effects of graft-versus-host disease on survival varying among different centers. We aimed to determine risk factors that may affect development of graft-versus-host disease and the corresponding patient survival rates at a single pediatric hematopoietic stem cell transplant unit.

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The aim of this study was to evaluate the results of an algorithm that was created to prevent coronavirus disease-2019 (COVID-19) transmission during the management of children with burns in a tertiary pediatric burn center. Children admitted to the burn center between May 2020 and November 2020 were prospectively evaluated for cause, burn depth, TBSA, length of stay, symptoms suggesting COVID-19, suspicious contact history, history of travel abroad, and COVID-19 polymerase chain reaction (PCR) test results. Patients were divided into two groups: unsuspected (group 1) and suspected (group 2), depending on any history of suspicious contact, travel abroad, and/or presence of symptoms.

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Background: Fever is one of the leading causes of hospital admissions in children. Although there are many ways to measure body temperature, the optimal method and the anatomic site are still controversial. In this study, we aimed to evaluate the performance of new methods of measuring body temperature and to compare the accuracy, sensitivity and specificity of these methods.

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Article Synopsis
  • The study analyzed pediatric COVID-19 cases across 32 hospitals in Turkey, focusing on the epidemiological, clinical, and laboratory characteristics of the disease in children from March 16 to June 15, 2020.
  • A total of 1,156 cases were confirmed, with a slightly higher proportion of males (50.3%) compared to females (49.7%), and the median age of the patients was 10.75 years; common symptoms included fever (50.4%) and cough (46.9%).
  • The severity of illness varied, with 22.7% asymptomatic, 57.7% experiencing mild symptoms, and 1.5% being classified as severe; 12.9% had
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Background: Healthcare-acquired infections (HAIs) in the neonatal period cause substantial morbidity, mortality, and healthcare costs. Our purpose was to determine the prevalence of HAIs, antimicrobial susceptibility of causative agents, and the adaptivity of the Centres for Disease Control and Prevention (CDC) criteria in neonatal HAI diagnosis.

Methods: A HAI point prevalence survey was conducted in the neonatal intensive care units (NICUs) of 31 hospitals from different geographic regions in Turkey.

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We report a case of neuro-ophthalmological complications of congenital toxoplasmosis, a parasitic infection caused by . Its congenital form occurs either as a primary infection or as reactivation of the same due to immunosuppression during pregnancy. With an incidence rate of 1.

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Background: Ralstonia pickettii is an opportunistic waterborne microbe which can survive in many kinds of solutions. Contamination of these solutions may result as outbreaks, which can be mortal for immuncompromised patients. Herein we report an outbreak of R.

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Objectives: Antimicrobial prophylaxis (AP) is an important means of reducing surgical site infections. The goal of this study was to evaluate the perioperative AP in paediatric practice and its compliance with surgical prophylaxis guidelines.

Methods: A prospective study was conducted at Gazi University Faculty of Medicine, between September 2015 and April 2016.

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