Synopsis of recent research by authors named "Tufail A Lone"
- Tufail A Lone's research primarily focuses on the genetic factors influencing colorectal cancer risk, particularly examining polymorphisms in DNA repair genes such as XRCC1 and XRCC3 among populations in Kashmir.
- A notable study revealed that the XRCC3 Thr241Met polymorphism may be linked to an increased risk of colorectal cancer, emphasizing the gene's role in maintaining genomic stability through DNA repair mechanisms.
- Another investigation into the XRCC1 Arg399Gln polymorphism found that while there was no direct significant association with colorectal cancer, specific genotypes like Arg/Gln may elevate the risk, suggesting a complex interaction between genotype and cancer susceptibility.
