Publications by authors named "Tudor Mateescu"
Article Synopsis
- - The review examines how natural compounds can work together with standard chemotherapy drugs to improve treatment outcomes for lung cancer patients, who currently face a low survival rate of just 18.1% over five years.
- - It emphasizes the drawbacks of traditional chemotherapy, particularly the resistance cancer cells can develop, and showcases how plant-based natural compounds have promising anticancer properties when used in conjunction with these drugs.
- - The findings suggest that combining anti-cancer drugs with natural compounds could enhance their effectiveness while potentially reducing side effects, offering a hopeful alternative for lung cancer treatment.
This study presents a systematic review of the literature on individuals' health-related quality of life (HRQoL) following radical cystectomy for muscle-invasive bladder cancer (MIBC), utilizing the Short Form-36 Health Survey (SF-36) as a primary assessment tool. The review was designed as an exhaustive literature search across three major databases including PubMed, Scopus, and Embase up to December 2023, using the PRISMA guidelines. The selection process refined 2281 identified articles down to 11 studies meeting our inclusion criteria.
View Article and Find Full Text PDFAnal fistulas often cause significant impairment to patients' health-related quality of life (HRQOL). This cross-sectional study aimed to compare the HRQOL between patients with anal fistulas with inflammatory bowel disease (IBD) and those without, hypothesizing significant differences in HRQOL scores between these groups. The secondary objectives were to identify specific aspects of life quality most affected and explore potential variables influencing HRQOL.
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- This study explores the link between developing bronchiectasis after lung surgery and the patients' overall quality of life (HRQoL), revealing potential long-term impacts.
- Out of 135 adult patients who had lung resections for suspicious nodules, 44 developed bronchiectasis within six months, leading to lower health status and increased anxiety.
- The findings highlight the need for continued monitoring of respiratory health in post-surgery patients, particularly those who develop bronchiectasis, due to the significant deterioration in quality of life and increased stress levels.
Article Synopsis
- The study compared outcomes and costs between primary lung cancer (PLC) and second primary lung cancer (SPLC) patients who underwent video-assisted thoracoscopic surgery (VATS), analyzing 124 patients between January 2018 and January 2023.
- Results indicated that SPLC patients had longer operative times (300 min vs. 260 min), longer hospitalization (6.1 days vs. 4.2 days), and higher total hospitalization costs (15,400 RON vs. 12,800 RON) compared to PLC patients.
- Survival rates were significantly lower in the SPLC group, with a 2-year survival of 24.2% for SPLC versus 41.
Diverticular disease is a common gastrointestinal disorder with increasing prevalence in advanced age. This study aimed to investigate the impact of age and complexity of diverticulitis on health-related quality of life (HRQoL) and stress-related disorders. A cross-sectional study was conducted on 180 patients, including adults (18-64 years) with complicated diverticular disease, the elderly (≥65 years) with complicated diverticular disease, and a control group with uncomplicated symptomatic diverticular disease.
View Article and Find Full Text PDFAnal Canal Duplication in an Adult Female-Case Report and Pathology Guiding.
Medicina (Kaunas)
November 2021
Anal canal duplication (ACD) is a very rare condition, diagnosed and treated mostly in childhood. Less than 90 cases have been reported in the literature so far. We are presenting a case of a young woman who underwent surgical excision of the duplication when she was 27 years old.
View Article and Find Full Text PDFSynchronous malignant lesions will always entail treatment related difficulties which would ideally require discussions within a multidisciplinary committee in such a way as to reach the optimal solution for the patient. Presented herewith are two patients suffering from lung cancer and clear cell renal carcinoma contralateral metastases and the treatment alternatives that I have opted for.
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- Pulmonary metastasectomy is a surgical procedure used to remove lung metastases, but it's unclear how much patients actually benefit from it and how to best combine it with cancer treatments like chemotherapy or radiotherapy.
- * Careful patient selection based on clinical staging and prognostic indicators is crucial for achieving good outcomes in these surgeries.
- * A collaborative approach involving a multidisciplinary team is essential for managing patients undergoing pulmonary metastasectomy effectively.