Diagnosis of juvenile nasopharyngeal angiofibroma by computed tomography.

Juvenile nasopharyngeal angiofibroma is a highly vascular neoplasms that tends to spread in the various fissures and foraminia of the nasopharynz. Polytomography and angiography have added greatly to the diagnosis and management of this tumor through accurate preoperative assessment. Computed tomography has given an additional sophisticated, precise method for evaluating the extent of juvenile nasopharyngeal angiofibroma.

Glottic reconstruction after near total laryngectomy.

It is generally accepted that vertical partial laryngectomy can yield satisfactory cure rates in properly selected glottic carcinomas. Several authors have discussed different reconstructive techniques following extended vertical partial laryngectomy. These have included the use of stents, keels, various soft tissue "free" grafts, or muscle transplants.

Management of the patient with an incompetent larynx.

Incompetency of the larynx may vary from minimal occasional aspiration of saliva with a somewhat annoying cough to severe and life threatening aspiration. Management of these problems remains a significant challenge to the ingenuity of the well trained otolaryngologist. A review of the anatomic and physiologic factors involved both in normal function of the larynx and in derangement resulting in varying degrees of laryngeal incompetency would seem worthwhile.

Reinnervation of the paralyzed larynx: a review.

Our high-speed and increasingly aggressive society, coupled with a continuing rise in necessary surgery of the neck and adjacent areas, accounts for the current increase in patients affilicted with vocal-cord paralysis. Such patients may sustain relatively little persistent loss of function (e.g.

Regulation of cortisol uptake in mammary tissue of cows.

Mammary tissue explants from four nonlactating, nonpregnant cows were placed into culture with media containing various combinations of insulin, prolactin, growth hormone, 17beta-estradiol, dexamethasone, and progesterone. Combinations of insulin, prolactin, growth hormone, or 17beta-estradiol had no effect on cytoplasmic or nuclear uptake of tritiated cortisol compared with values at zero time. Combinations containing dexamethasone of progesterone reduced cytoplasmic and nuclear uptake of tritiated cortisol.

Effects of processing milk on concentrations of glucocorticoids in milk.

Concentrations of glucocorticoids were measured by protein binding in milk subjected to various processing methods. Raw whole milk was collected once per week for 3 wk from bulk milk tanks of each of 10 farms. Nine combinations of processing were tested: 1) none, 2) high-temperature short-time pasteurization of whole milk, 3) high-temperature short-time pasteurization and homogenization of whole milk, 4) bulk pasteurization of whole milk, 5) bulk pasteurization and homogenization of whole milk, 6) high-temperature short-time pasteurization of skim milk, 7) high-temperature short-time pasteurization and homogenization of skim milk, 8) bulk pasteurization of skim milk, and 9) bulk pasteurization and homogenization of skim milk.

Achalasia secondary to carcinoma: manometric and clinical features.

The clinical and diagnostic features of a secondary type of achalasia of the esophagus are described in seven patients with various types of malignancies. Patients with secondary achalasia presented with dysphagia of short duration and marked weight loss; mean age was 64 years. Esophageal manometry showed features identical to those of idiopathic primary achalasia: aperistalsis, poor lower esophageal sphincter relaxation, and elevated sphincter pressure.

Recurrent laryngeal nerve pathology in spasmodic dysphonia.

Since it was first described in 1871, spasmodic (spastic) dysphonia has been considered a disease of psychogenic origin. Unsupported theories of possible organic etiology have appeared sporadically in the literature. In 1976 sectioning of the recurrent laryngeal nerve for patients with this disease was reported with resultant improvement in voice production.

beta-Adrenergic blocking agents. 18. 1-(Aryloxy)-3-(arylthioalkylamino)propan-2-ols and 1-substituted alkylthioamino-3-(aryloxy)propan-2-ols.

The synthesis is described of a seris of derivaties of 1-(aryloxy)-3-(arylthioalkylamiho)propan-2-ols and 1-(alkylthioamino)- and 1-(aralkylamino)-3-(aryloxy)propan-2-ols. These compounds were investigated for their beta-adrenoreceptor blocking properties and their selectivity of action for the cardiac beta1 receptor. The structure-activity relationships are discussed with particular reference to the effects of the sulfur, sulfoxide, and sulfone groups on beta-adrenoreceptor blocking potency and selectivity.

Glucocorticoids in mammary secretions and blood serum during reproduction and lactation and distributions of glucocorticoids, progesterone, and estrogens in fractions of milk.

Concentrations of glucocorticoids were measured in milk and blood serum during the estrous cycle, prepartum, parturition, postpartum, and early and late lactation. Glucocorticoids in milk did not change during the estrous cycle, averaging .35 ng/ml whereas they averaged .

Human laryngeal reinnervation: long-term experience with the nerve-muscle pedicle technique.

The nerve-muscle pedicle technique for reinnervation of bilateral vocal cord paralysis has now been applied in 45 cases over the past four years. EMG studies, volume flow loop, pulmonary function studies, and the ability to extubate the patient with good to excellent exercise tolerance for day-to-day activity have been used as parameters to judge success or failure of this procedure. To date there has been a primary success rate of 91.

Assessing the psychological effects of an exercise training programme for patients following myocardial infarction: a pilot study.

During a study investigating physiological and other effects of an exercise programme for coronary patients, a questionnaire was administered. Preliminary analysis had suggested some improvement in the patients' morale, but in view of the possible relevance of a number of psychological variables it was decided to carry out further analysis on the available data. The coefficient of discrimination was computed for 32 patients.

Diagnosis of juvenile angiofibroma by computed tomography.

Computed tomography (CT) accurately localized juvenile angiofibromata in 3 patients. The expanded pterygopalatine fossa and canal were visualized by CT in all three cases. Because of the hemorrhagic tendency of these tumors, a noninvasive modality such as CT is especially valuable in planning therapy.

Supplemental lighting stimulates growth and lactation in cattle.

Sixteen hours of light daily (114 to 207 lux) increased weight gains and milk yield 10 to 15% in Holstein cattle in comparison with cattle exposed to natural-length photoperiods (39 to 93 lux) of 9 to 12 hours. The weight gain was accomplished without increased consumption of feed. Manipulation of supplemental light may thus cause dramatic increases in food supplies from animals.

New trends in the management of diabetic ketoacidosis.

The diagnosis of ketoacidosis can be rapidly confirmed by simple determinations of blood glucose, serum ketones and arterial pH. The initial hydrating fluid is isotonic saline, followed by half-normal saline with buffered potassium phosphate. As soon as the blood glucose drops below 300 mg.

The management of facial paralysis due to extracranial injuries.

Improvements in surgical capabilities in the management of malignancies about the ear and parotid gland, increasing vehicular and interpersonal trauma, and greater concern with cosmetic factors by the public at large, have led to increasing need for the surgeon's ability to manage injuries to the facial nerve. Several important anatomic, physiologic and technical factors bear upon a logical approach to repair of such facial nerve injuries. Careful attention to these concepts had led to satisfactory return of facial function in most cases managed by the author.