Four new polyhydroxy pregnane glycosides, named volubilosides G-K (3, 5-7), along with three known secondary metabolites, dregeoside D (1), dregeoside K (2), and volubiloside E (4) were isolated from the twigs and leaves of Dregea volubilis (DV). The chemical structures of these compounds (1-7) were elucidated using spectroscopic techniques (1D and 2D NMR and HR-ESI-MS analyses) and compared with those in the published literature. Compounds (1-7) were evaluated for cytotoxicity against eight cancer cell lines (MB49, K562, MKN-7, HT29, A549, MCF-7, MDA-MB-231, and HepG2), revealing varying levels of cytotoxic effects with IC values ranging from 4.
View Article and Find Full Text PDFRecently, many methods have been developed to efficiently eliminate oil spills due to its long-term harmful effects on marine life and human health. Expanded graphite (EG) has been considered as an excellent platform to remove contaminated oil from aqueous solution through a facile adsorption route. As an innovative approach, the decoration of magnetic components, namely, MnFeO, into graphite layers was taken into account for facilitating phase separation under magnetic field which resulted into an easy collection of the used adsorbents in a large scale.
View Article and Find Full Text PDFWe systematically searched and meta-analyzed the epidemiological characteristics, frequency of clinical signs, and outcomes of dengue-associated hemophagocytic lymphohistiocytosis. Ten electronic databases were searched systematically plus manual search of reference lists to identify relevant articles published until May 2017. The highest number of reported cases were from South-East Asia region (62 cases), followed by Western Pacific region (20 cases), and America (31 cases).
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