Publications by authors named "Tuan Anh Dang"
Article Synopsis
- Non-obstructive azoospermia (NOA) is a prevalent and complex issue with varied treatment options and no definitive guidelines, leading to differing management practices internationally.
- A comprehensive survey with 336 responses from specialists in 49 countries explored current medical and surgical strategies for NOA, analyzing results against existing guidelines and offering expert recommendations.
- Key findings included diverse approaches to hormonal therapy, significant variation in sperm retrieval success rates, and differing protocols around varicocele repair and follicle-stimulating hormone cutoff levels for sperm retrieval.
Article Synopsis
- * Conducted from July to September 2022, a questionnaire gathered responses from 367 doctors in 49 countries, focusing on how they diagnose NOA through methods like hormone tests and genetic analyses.
- * The survey identified that while many practices align with guidelines, significant differences in approaches were found, underscoring the need for standardized, evidence-based international guidelines for NOA evaluation.
A simple and economical process for producing amantadine hydrochloride () on a 250 g scale, an antiviral and anti-Parkinson drug, has been developed. Several methods for the preparation of through intermediate -(1-adamantyl)-acetamide () in four or three steps were reported. These procedures started with adamantine () or 1-bromoadamantane (), acetonitrile, and sulfuric acid by using the Ritter-type reaction to obtain -(1-adamantyl)-acetamide, which was deacetylated to afford 1-amino-adamantane () and then the salt formed with anhydrous HCl gives with the overall yield of being 50-58%.
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