Publications by authors named "Tu Thanh Tran"

Article Synopsis
  • * The results showed that using the probiotic significantly reduced recovery time by 2 days and improved treatment effectiveness by 58% in alleviating all related symptoms.
  • * Additionally, it decreased viral loads and inflammatory markers in patients, indicating it could be a promising, cost-effective option for managing respiratory viral infections in children.
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Respiratory syncytial virus (RSV) is a leading cause of Acute Respiratory Tract Infections (ARTIs) in young children. However, there is currently no vaccine or treatment available for children. Here, we demonstrated that nasal-spraying probiotics containing 5 billion of Bacillus spores (LiveSpo Navax) is an effective symptomatic treatment in a 6-day randomized controlled clinical study for RSV-infected children (n = 40-46/group).

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Alzheimer's disease (AD) is the most common type of dementia and also one of the leading causes of death worldwide. However, the underlying mechanisms remain unclear, and currently there is no drug treatment that can prevent or cure AD. Here, we have applied the advantages of using induced pluripotent stem cell (iPSC)-derived neurons (iNs) from AD patients, which are able to offer human-specific drug responsiveness, in order to evaluate therapeutic candidates for AD.

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