Isolated Diffuse Bone Marrow Metastases From Signet-ring Cell Gastric Carcinoma.

A 71-year-old female patient with a known history of signet-ring cell carcinoma presented with diffuse bone pain and anemic symptoms. An F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography study revealed diffuse heterogeneous hypermetabolic sclerotic lesions in the axial and proximal appendicular skeleton. No other F-FDG-avid lesions were detected.

Lincoln Sign: A Rare Presentation of Medication-related Osteonecrosis of the Jaw.

A 52-year-old female patient with metastatic breast cancer receiving denosumab for 7 years presented with marked diffuse tracer uptake in the mandible on Tc-99m-methylene diphosphonate bone scintigraphy, resembling the Lincoln sign. A diagnosis of medication-related osteonecrosis of the jaw (MRONJ) was confirmed, leading to immediate discontinuation of denosumab. Conservative therapy, including limited debridement and oral rinses, was initiated.

Loss of Mickey Mouse Ears' Sign in Progressive Supranuclear Palsy.

Progressive supranuclear palsy (PSP) is the most prevalent form of degenerative atypical parkinsonism. Clinical manifestations of PSP commonly encompass deficits in vertical gaze, postural stability, akinesia, and cognitive impairment. The characteristic metabolic pattern observed in PSP through FDG PET displays hypometabolism in the midbrain, striatum, thalamus, and frontal lobe.

18 F-FDG PET/CT in Synovial Anaplastic Large Cell Lymphoma.

Anaplastic large cell lymphoma is an uncommon and aggressive form of peripheral T-cell lymphoma. Synovial anaplastic large cell lymphoma is very rare. We present PET/CT findings in a patient with synovial anaplastic large cell lymphoma.

Bone Health Status of Children with Spinal Muscular Atrophy.

Background: Spinal muscular atrophy (SMA) is a group of rare, inherited neuromuscular disorders. Bone health is often a neglected issue in children with SMA. This study aimed to evaluate the bone health status of children with SMA in Hong Kong.

Abnormal Cerebral FDG Accumulation in Acute Intracerebral and Subarachnoid Hemorrhages Due to Different Mechanisms.

Changes in cerebral glucose metabolism after acute intracranial hemorrhage have been rarely described. We present a patient with abnormal cerebral FDG accumulation in acute intracerebral and subarachnoid hemorrhages due to different mechanisms on FDG PET/CT. The patient received conservative management and died 2 months later.

Unexpected FDG Uptake in the Cerebral Parenchyma in Subacute Subarachnoid Hemorrhage.

Changes in cerebral glucose metabolism after subarachnoid hemorrhage have been rarely described. We present a case with subacute subarachnoid hemorrhage showing unexpected elevated FDG uptake at adjacent cerebral parenchyma on FDG PET/CT. The density of the cerebral parenchyma was normal on CT.

Hepatic Superscan in Methotrexate-Associated Lymphoproliferative Disorder.

A 60-year-old man on methotrexate for treatment of adult-onset Still disease presented with acute onset of fever, pancytopenia, and deranged liver function. Besides FDG-avid lesions in spleen and skeleton, his 18 F-FDG PET/CT study showed diffuse and intense uptake in the liver with significantly suppressed heart and brain activity (reminiscent of a hepatic superscan). Subsequent biopsy confirmed the diagnosis of methotrexate-associated lymphoproliferative disorder.