Publications by authors named "Tsz Ching Mok"
The Potential Use of Arsenic Trioxide in the Treatment of Systemic Lupus Erythematosus.
Int J Mol Sci
September 2024
Article Synopsis
- Arsenic trioxide (ATO) is now being used to treat a type of leukemia and has a safer oral form that causes less heart damage compared to the old IV method.
- ATO may help with autoimmune diseases by affecting certain immune cells and reducing harmful antibodies in the body.
- It could be a promising treatment for systemic lupus erythematosus (SLE) because it's easier to take, cheaper, and has fewer side effects than other new treatments.
Introduction: Rheumatoid arthritis (RA) is a chronic inflammatory rheumatic disease that affects both the articular and extra-articular structures, leading to significant joint damage, disability and excess mortality. The treatment algorithm of RA has changed tremendously in the past 1-2 decades because of the emergence of novel biological therapies that target different mechanisms of action in addition to TNFα.
Areas Covered: This article summarizes the evidence and safety of the non-TNF biological DMARDs in the treatment of RA, including those that target B cells, T-cell co-stimulation, interleukin (IL)-6 and granulocyte-monocyte colony-stimulating factor (GM-CSF).