Publications by authors named "Tsuyoshi Yoshita"

Article Synopsis
  • The text discusses a case of a 37-year-old woman who developed progressive hyperopia (blurred vision) three years after sustaining a traumatic cataract due to a posterior capsule tear from blunt eye trauma.
  • The injury led to a significant change in her vision, from emmetropia to +8.0 diopters, accompanied by lens damage and cataract formation observed via optical coherence tomography (OCT).
  • Following femtosecond laser surgery, she achieved 20/20 vision one month later, illustrating effective management of cataracts and hyperopia resulting from blunt trauma.
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Purpose: To measure the light transmission properties of human limbal epithelial cell sheets (LECSs) cultured on human amniotic membranes (AMs) and compare them with those of AMs with and without amniotic epithelium.

Methods: Total light transmission of 3 kinds of tissue (LECSs, intact AMs, denuded AMs) was measured in the 250- to 800-nm range by using a spectrophotometer.

Results: The percent transmission of each kind of tissue decreased gradually and continually throughout the spectrum as the wavelength shortened and dropped rapidly at 300 nm to less than 20% at 250 nm.

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A 9-month-old infant had bilateral corneal opacity with erosion in the inferior corneas. Clinical examination suggested the infant had congenital alacrima. After 1 week, both corneas perforated with collapsed anterior chambers.

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Background And Objective: Corneal epithelial sheet cultured on amniotic membrane ex vivo has been developed for the treatment of severe ocular surface disorders. In this study, human corneal epithelial sheets cultured on amniotic membranes were analyzed using a laser scanning confocal microscope.

Materials And Methods: Human corneal epithelial cells were cultured on four sheets of amniotic membrane, and they were examined layer by layer using the laser scanning confocal microscope.

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Purpose: To determine the reliability of noncontact tonometry (NCT) in measuring intraocular pressure (IOP) over a combination of amniotic membrane (AM) patch and therapeutic soft contact lens (TSCL) in normal human eyes.

Design: Experimental study.

Methods: Twenty-five healthy volunteers (twenty males, five females) participated in this study.

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Objective: To report successful management of acute stage toxic epidermal necrolysis (TEN) by amniotic membrane transplantation.

Design: Interventional case report. METHOD/INTERVENTION: A 6-year-old boy who had convulsions and fever due to encephalitis was treated by oral phenobarbital.

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Objective: To report in vivo laser scanning confocal microscopic findings of the normal human conjunctiva and presumed meibomian glands and to investigate the potential application of this confocal microscope (HRT II Rostock Cornea Module) as a diagnostic device for normal and abnormal ocular surface structures.

Method: Four healthy volunteers (51-, 49-, 31-, and 30-year-old men) participated in this study. The temporal bulbar conjunctiva, approximately 5 mm away from the limbus, and the upper tarsus conjunctiva of each patient were examined in vivo by a laser confocal microscope.

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Background And Objective: To report in vivo laser and white-light confocal microscopic findings of human conjunctiva to investigate the potential application of these confocal microscopes as diagnostic devices for normal and pathologic conjunctiva.

Patients And Methods: Two healthy volunteers, 28- and 35-year-old men, participated in this study. The temporal bulbar conjunctiva, which was approximately 5 mm away from the limbus, was examined by in vivo laser and white-light confocal microscopic analysis.

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Purpose: To investigate the oxygen permeability (Dk) and oxygen transmissibility (Dk/t) of amniotic membrane (AM), and tear oxygen tension beneath AM in rabbits.

Design: Experimental study.

Method: The water content of AM was measured to calculate Dk and Dk/t, and compared with those of a therapeutic soft contact lens (TSCL).

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Purpose: To determine the reliability of Tono-Pen XL in measuring intraocular pressure (IOP) over the amniotic membrane patch in human eyes.

Method: Ten healthy volunteers (nine males and one female) participated in this study. After topical anesthesia, IOP was measured using the Tono-Pen XL before and after the application of a single-layer amniotic membrane patch in the right eye and double-layer amniotic membrane patch in the left eye.

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Background And Objective: To report laser and white-light confocal microscopic findings of ex vivo rabbit conjunctiva to investigate the potential application of these confocal microscopes as diagnostic devices for normal and pathologic conjunctiva.

Materials And Methods: Three male albino rabbits were killed and six eyeballs were removed with as much bulbar conjunctiva as possible. The bulbar conjunctiva approximately 5 mm away from the limbus was then subjected to an ex vivo laser and white-light confocal microscopic analysis.

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Purpose: To report confocal microscopic observation of rabbit corneal epithelium through amniotic membrane patch (AMP).

Design: Experimental study.

Method: Six rabbit eyes were patched by amniotic membrane.

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Purpose: To report an accuracy of intraocular pressure (IOP) by Tono-Pen XL over amniotic membrane patching in rabbits.

Design: Experimental study.

Methods: Seven male albino rabbits were used in this study.

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Background: Interferon alpha-2b (IFN alpha 2b) was recently shown to be effective as an alternative therapy for conjunctival intraepithelial neoplasia (CIN). Herein, we report our successful management of CIN by the use of IFN alpha 2b.

Case: A 73-year-old woman presented with a complaint of irritation due to a tumorous lesion in her left eye.

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