Publications by authors named "Tsutsumi A"

Introduction: Rising pediatric firearm-related fatalities in the United States strain Trauma Centers. Predicting trauma volume could improve resource management and preparedness, particularly if daily forecasts are achievable. The aim of the study is to evaluate various machine learning models' accuracy on monthly, weekly, and daily data.

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Objectives: This systematic review aimed to assess the association between psychosocial factors in the workplace and menstrual abnormalities or fertility, focusing on literature implementing a prospective cohort design.

Methods: We searched MEDLINE, EMBASE, PsycINFO, PsycARTICLES, and Japan Medical Abstracts Society electronic databases for studies published from inception to February 26, 2020, and updated the search in PubMed on May 29, 2024. Inclusion criteria were (P) adult female workers (over 18 years old), (E) presence of adverse psychosocial factors at work, (C) absence of adverse psychosocial factors at work, and (O) any menstrual cycle disorders, menstrual-related symptoms, or fertility issues.

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The use of prenatal testing in Japan is expected to increase. However, there are ethical concerns regarding pregnancy termination upon the detection of fetal chromosomal abnormalities, such as Down syndrome. Furthermore, factors associated with decision-making following a positive result of Down syndrome after prenatal screening remain unclear.

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Background: During the COVID-19 pandemic, health care professionals experienced high levels of depression. However, extant research has not highlighted effective internet-based psychological interventions to improve the mental health in this population during the pandemic. It remains unclear whether self-guided, internet-based cognitive behavioral therapy (iCBT) programs are effective in improving the mental health of health care workers during the COVID-19 pandemic.

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Background/aim: Flavonoids represent a privileged scaffold for medicinal chemists because of versatile synthetic transformation into a large variety of functionalized derivatives and are known to exhibit a variety of biological activities and their potential as anticancer agents is being investigated. As part of our continuing investigation of flavonoid derivatives as potential anticancer substances, a series of 3-methylflavones were synthesized, and their antiproliferative activity was evaluated in leukemic HL60 cells.

Materials And Methods: 3-Methylflavones were directly synthesized from the 2-propionylphenyl benzoate esters prepared from combination of 2'-hydroxypropiophenone with appropriate benzoic acid derivatives by the modified conditions of Yamaguchi esterification.

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The association between doctors' long working hours and the seriousness of adverse events with high patient impact has not been fully confirmed. Most previous studies were based on work hour regulations using more than 80 hours per week as an indicator of long working hours. We aimed to assess the association using a shorter indicator as the cut-off for long working hours among hospital doctors including senior doctors.

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Introduction: Asian American and Native Hawaiian-Pacific Islanders (AAPI) are the fastest growing racial-ethnic group, with 18.9 million people in 2019, and is predicted to rise to 46 million by 2060. Colorectal cancer (CRC) is the most common cancer in AAPI men and the third most common in women.

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Background: Internet psychoeducational interventions improve employees' mental health. However, implementing them for employees in micro- and small-sized enterprises (MSEs) is challenging.

Objectives: This randomized controlled trial examined the effectiveness of a fully automated text-based stress management program, "WellBe-LINE," in improving mental health and job-related outcomes for employees in workplaces with fewer than 50 employees.

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Background: This study aimed to examine whether online interactive communication education using video materials was as effective as face-to-face education among healthcare college students.

Methods: The participants were healthcare college students who were enrolled in study programs to obtain national medical licenses. They participated in lectures and exercises on healthcare communication, both online (n = 139) and face-to-face (n = 132).

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Article Synopsis
  • The text outlines the importance of participatory organizational interventions for improving psychosocial working conditions and highlights a lack of systematic reviews on their impact on mental health and work performance.
  • The study aims to conduct a systematic review and meta-analysis using specific criteria (PICO) to evaluate the effects of these interventions, focusing on workers’ mental health and job performance.
  • Researchers will search multiple electronic databases for relevant studies, independently assess study quality, and conduct statistical analyses to determine the overall effects and potential biases in the findings.
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Article Synopsis
  • Megalin is a large glycoprotein involved in endocytosis, handling over 60 different compounds, and is primarily found in kidney cells but also in other organs like the brain and lungs.
  • It plays a role in the uptake of both helpful and toxic substances, with a genetic deficiency leading to serious syndromes related to multiple organ issues.
  • The study used cryoelectron microscopy to reveal the structure of megalin and its interactions with ligands and a chaperone protein, providing insights for future research on diseases and potential drug development targeting megalin.
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Objective/background: To clarify whether mobile sleep applications alleviate insomnia symptoms among adults from multi-community.

Patients/methods: A literature search was conducted using the PubMed, Cochrane, PsycINFO, and Web of Science databases for articles related to mobile technology and sleep interventions published between database inceptions and March 27, 2023. We pooled relevant data using a random-effects model, and a meta-analysis was performed using a web version of the Cochrane Review Manager.

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Background: Although internet-based stress management programs are proven effective in improving mental health among workers, micro- and small-sized enterprises (MSEs), lacking in occupational healthcare services, face challenges implementing them. To address this gap, this study will develop the program with stakeholders at MSEs to aim for real-world implementation.

Objectives: This paper describes a study protocol for a pre-post feasibility study of an effectiveness-implementation hybrid type 2 trial of text-based internet-based programs ("WellBe-LINE") in MSEs with less than 50 employees.

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Background: Depression and anxiety are the most common mental health issues experienced by workers. Although organizational intervention has been extensively evaluated as a primary prevention of depression and anxiety, the corresponding scientific evidence remains limited because of the lack of cluster randomized controlled trials (cRCT) and failure to detect organizational-level effects. Therefore, the present study aims to assess the preventive effects of four types of interventions on depression and anxiety among workers in an open, five-arm, parallel-group cRCT.

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Appendicitis is an inflammatory condition that requires timely and effective intervention. Despite being one of the most common surgically treated diseases, the condition is difficult to diagnose because of atypical presentations. Ultrasound and computed tomography (CT) imaging improve the sensitivity and specificity of diagnoses, yet these tools bear the drawbacks of high operator dependency and radiation exposure, respectively.

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This study compares the traumatic and human rights violation experiences of persons with mental health conditions or psychosocial disabilities and those of persons with other disabilities in the Philippines. Additionally, the role of gender in exposure to traumatic experience and human rights protection levels is explored. Of those registered as persons with disabilities in the city of Muntinlupa, 3000 subjects were randomly selected and 1,024 among them (Male = 510, Female = 512, Others = 2) agreed to participate in this study.

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Article Synopsis
  • The study focused on a new smartphone app called ASHARE designed to improve physical activity and reduce depression and anxiety among working individuals by using deep learning models for monitoring mental health based on physical activity levels.
  • Researchers aimed to assess the app's effectiveness and its implementation outcomes, including user satisfaction and feasibility, through a month-long trial with employees aged 18 and older.
  • Measurements included self-reported physical activity and psychological distress before and after using the app, with statistical analyses performed to evaluate changes and user experience compared to previous studies.
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Introduction: Video-based surgical coaching is gaining traction within the surgical community. It has an increasing adoption rate and growing recognition of its utility, especially an advanced continuous professional growth tool, for continued educational purposes. This method offers instructional flexibility in real-time remote settings and asynchronous feedback scenarios.

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Bronchiectasis is a chronic respiratory condition characterized by irreversible bronchial dilation, often caused by infection or inflammation. It can be associated with primary ciliary dyskinesia (PCD), a hereditary disorder affecting cilia function in various organs and flagella. PCD's genetic heterogeneity leads to varying disease severity.

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Objective: We aim to investigate the quantity and quality of scientific evidence dealing with comprehensive health issues of working women in occupational health.

Methods: This scoping review of original articles that investigated comprehensive health issues of working women aged 19-64 years in Japan was published in PubMed (1967-2022) and Igaku Chuo Zasshi (or Ichu-shi, 1982-2022). Using identical broad search terms, we first identified 17 122 English and 6154 Japanese articles.

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Background: We sought to examine differences in outcomes for Black and White patients undergoing robotic or laparoscopic colectomy to assess the potential impact of technological advancement.

Methods: We queried the ACS-NSQIP database for elective robotic (RC) and laparoscopic (LC) colectomy for cancer from 2012 to 2020. Outcomes included 30-day mortality and complications.

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Zinc ions (Zn) are vital to most cells, with the intracellular concentrations of Zn being tightly regulated by multiple zinc transporters located at the plasma and organelle membranes. We herein present the 2.2-3.

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