Comparison of hook wire and microcoil preoperative localisation in subsolid pulmonary nodules: a retrospective analysis.

Aim: Subsolid nodules are increasingly detected during physical examinations with computed tomography (CT) scan and video-assisted thoracoscopic surgery (VATS) is the standard treatment. This study compared the effectiveness of preoperative localisation of subsolid pulmonary nodules using a hook-wire and a microcoil under CT guidance prior to VATS.

Materials And Methods: Patients with solitary subsolid pulmonary nodules (n = 342) underwent percutaneous puncture localisation guided by CT before VATS.

An Eye-Tracking-Based Investigation on the Principle of Closure in Logo Design.

This study employs subjective evaluation and eye movement experiments to explore the application and conveyance of logo graphics design, which conforms to the Gestalt principle of closure, to understand the psychological process of this principle in the perception of a logo. The study found that there is no significant difference between completely enclosed logos and unenclosed ones that conform to the principle of closure in their influence on sightline behavior due to the effects of closure, but the subjective evaluation favors unenclosed logos as more attractive and comfortable to perceive, which agrees with modern logo design trends. In addition, the sightline distribution of the image-type logos is more scattered and has the most extended fixation duration.

Impact of Leading Line Composition on Visual Cognition: An Eye-Tracking Study.

Leading lines, a fundamental composition technique in photography, are crucial to guiding the viewer's visual attention. Leading line composition is an effective visual strategy for influencing viewers' cognitive processes. However, in-depth research on the impact of leading line composition on cognitive psychology is lacking.

Longitudinal Changes in Patient- and Clinical-Reported Outcomes in Early Spinocerebellar Ataxia Types 1, 2, 3, and 6 from the IDEA Study.

Background: Clinical outcomes assessments (COAs) in spinocerebellar ataxia (SCA) need to be standardized, ataxia-specific, sensitive to change, clinically relevant, and meaningful to patients.

Objectives: To evaluate the longitudinal 1- and 2-year performances of different patient reported outcomes, including the Patient Reported Outcome Measure of Ataxia (PROM-Ataxia), and clinician reported outcomes, including FARS and SARA, in those with early manifest symptoms of SCA 1, 2, 3, and 6.

Methods: We studied 53 patients with early stage SCA1-3 and SCA6 from The Instrumented Data Exchange for Ataxia Study and 24 age-matched healthy controls.

Ventilatory variables and computed tomography features in COVID-19 ARDS and non-COVID-19-related ARDS: a prospective observational cohort study.

Background: This study compared the ventilatory variables and computed tomography (CT) features of patients with coronavirus disease 2019 (COVID-19) versus those of patients with pulmonary non-COVID-19-related acute respiratory distress syndrome (ARDS) during the early phase of ARDS.

Methods: This prospective, observational cohort study of ARDS patients in Taiwan was performed between February 2017 and June 2018 as well as between October 2020 and January 2024. Analysis was performed on clinical characteristics, including consecutive ventilatory variables during the first week after ARDS diagnosis.

Oxidative Scission of Bicyclo[2.2.2]octenones: Untying the α-Dimethoxycarbonyl.

This study explores the selective oxidative scission of bicyclo[2.2.2]octenones derived from masked -benzoquinones (MOBs).

Use of Electronic Health Records to Identify Factors Related to Skin Changes in Terminal Patients.

Objective: To investigate the incidence of skin changes at life's end (SCALE) among hospice patients and identify associated factors.

Methods: The authors conducted a retrospective chart review of demographic data, medical history, Braden Scale assessment scores, Charlson Comorbidity Index, symptom records, and medical treatments of patients admitted to a local teaching hospital's hospice unit between May 2019 and April 2021.

Results: Most (79%) of the 300 hospice patients included in the study had cancer.

Riboflavin-ultraviolet-A collagen crosslinking treatments in improving dentin bonding and resistance to enzymatic digestion.

Background/purpose: The efficacy of riboflavin-ultraviolet-A (RF-UVA) treatment in crosslinking collagen and improving dentin bonding has been proven. However, biodegradation of the hybrid layer may compromise the bonding. The purpose of this study was to evaluate different RF-UVA treatments regarding their ability to preserve dentin bonding from enzymatic digestion.

Elucidating interfacial failure of cervical restorations using damage mechanics: A finite element analysis.

Background/purpose: Although clinical studies have suggested a link between non-axial forces and reduced longevity of cervical restorations, the underlying mechanisms require further numerical investigation. This in-silico study employed a cohesive zone model (CZM) to investigate interfacial damage in a cervical restoration subjected to different load directions.

Materials And Methods: A plane strain model of a maxillary premolar was established, with a wedge-shaped buccal cervical restoration.

Comparisons of precision and trueness of digital dental casts produced by desktop scanners and intraoral scanners.

Background/purpose: Different types of scanners are gradually used to produce digital dental casts in the current dental practice. This study tested the accuracy of the three desktop scanners and two intraoral scanners and evaluated whether the desktop scanners had higher precision than the intraoral scanners.

Materials And Methods: This study used the three desktop and two intraoral scanners to scan a standard dental cast 5 times.

Specialty education and scope of oral and maxillofacial surgery in the United States.

In the United States, Oral and Maxillofacial Surgery (OMS) is a specialty of dentistry that focuses on the management of injuries, diseases, and defects of the head, neck, face, and jaws. The present manuscript is an article on education and training of OMS residents in the United States. It a lso briefly describes the scope of practice of the specialty.

Evaluation of cortical bone thickness at the nasomaxillary and zygomaticomaxillary buttresses using cone-beam computed tomography imaging for Le Fort I osteotomy.

Background/purpose: Studies have indicated that 50%-55% of the population have malocclusion, and approximately 5%-10% require orthognathic surgery to correct this condition. Optimal placement of plates and screws significantly affects the success rate of the surgery and postoperative stability. This study evaluates the cortical thickness of the maxillary bone in the nasomaxillary and zygomaticomaxillary buttress regions in Taiwanese patients based on cone-beam computed tomography (CBCT) images.

Is History of Cardiovascular Disease Associated with Increased Caries Experience among Taiwanese Adults?

Introduction: This study examined the association between cardiovascular disease (CVD) history and their dental caries experience status.

Methods: Conducted from January 2021 to June 2023, this cross-sectional cohort study involved 7,138 participants who underwent oral examinations. Data on demographic background, oral health-related behaviors, and smoking status were collected using a structured questionnaire.

The Delusional Hedge Algorithm as a Model of Human Learning From Diverse Opinions.

Whereas cognitive models of learning often assume direct experience with both the features of an event and with a true label or outcome, much of everyday learning arises from hearing the opinions of others, without direct access to either the experience or the ground-truth outcome. We consider how people can learn which opinions to trust in such scenarios by extending the hedge algorithm: a classic solution for learning from diverse information sources. We first introduce a semi-supervised variant we call the delusional hedge capable of learning from both supervised and unsupervised experiences.

Bioabsorbable magnesium-based bulk metallic glass composite (BMGC) for improved medial opening wedge high tibial osteotomy in knee osteoarthritis.

Background And Objective: Osteoarthritis is a widespread and debilitating condition, particularly affecting the medial compartment of knee joint due to varus knee deformities. Medial opening wedge high tibial osteotomy (MOWHTO) has emerged as an effective treatment, but it comes with challenges like fractures, correction loss, and nonunion, leading to unsatisfactory results in up to 26 % of patients. In response, our study explores the potential of a bioabsorbable magnesium-based bulk metallic glass composite (MgZnCa BMGC) enriched with molybdenum particles as an innovative solution for MOWHTO.

MCU-i4, a mitochondrial Ca uniporter modulator, induces breast cancer BT474 cell death by enhancing glycolysis, ATP production and reactive oxygen species (ROS) burst.

Objectives: Mitochondrial Ca uniporter (MCU) provides a Ca influx pathway from the cytosol into the mitochondrial matrix and a moderate mitochondrial Ca rise stimulates ATP production and cell growth. MCU is highly expressed in various cancer cells including breast cancer cells, thereby increasing the capacity of mitochondrial Ca uptake, ATP production, and cancer cell proliferation. The objective of this study was to examine MCU inhibition as an anti-cancer mechanism.

Platelet extracellular vesicles-loaded hydrogel bandages for personalized wound care.

Autologous or allogeneic platelet-derived extracellular vesicles (pEVs) show potential in enhancing tissue recovery and healing chronic wounds. pEVs promote neovascularization and cell migration while reducing inflammation, oxidative stress, and scarring. However, their efficacy in clinical settings is challenged by their susceptibility to washout by wound exudate.

Impact of Oseltamivir and Diabetes Development.

: Influenza is a major global health challenge, causing thousands of deaths annually. Antiviral drugs, particularly oseltamivir, a neuraminidase inhibitor, have become essential therapeutic options due to their oral bioavailability and efficacy. Previous studies suggest a potential association between oseltamivir use and the onset of diabetes mellitus.

Divergent Effects of Capsid Proteins on Type I Interferon Signaling.

Viruses in the family can infect mammals and birds. Porcine circovirus type 2 (PCV2) significantly affects the livestock industry by causing porcine circovirus-associated diseases, such as postweaning multisystem wasting syndrome, respiratory disease complex, and dermatitis nephropathy syndrome. Additionally, beak and feather disease virus in parrots, canine circovirus in dogs, and columbid circovirus (pigeon circovirus) in racing pigeons induce immunosuppression, followed by secondary infections in these hosts.

Therapeutic Potential of Bioactive Peptides Derived from Natural Products of Tortoiseshell and Antler in Alleviating Osteoporosis and Osteoarthritis.

Tortoiseshell and antler, the main components of , are natural products that can be used as traditional Chinese medicine (TCM) to alleviate osteoporosis and osteoarthritis. However, research on the active ingredients in tortoiseshell and antler for alleviating osteoporosis and osteoarthritis remains insufficient. This study primarily compares the antioxidant capacity of tortoiseshell gelatin and antler gelatin and their bioactive peptides, as well as their effects on the cell viability of MC3T3-E1 osteoblasts and HIG-82 chondrocytes.

Citric Acid Improves Egg White Protein Foaming Characteristics and Meringue 3D Printing Performance.

Meringue has limited the use of meringue for personalization because of its thermally unstable system. Citric acid (CA) enhancement of egg white protein (EWP) foaming properties is proposed for the preparation of 3D-printed meringues. The results showed that CA increased the viscosity, exposure of hydrophobic groups (79.

Comprehensive Characterization of Overt Myelofibrosis in an Asian Cohort: Phenotype, Mutation Landscape and Discordance Among Scoring Systems.

Various prognostic scoring systems in myelofibrosis (MF) have been developed to guide clinical decision-making in MF. However, discrepancies between different scoring systems for individual patients remain poorly understood, which can result in conflicting treatment recommendations. Moreover, data regarding there applicability in Asian populations remain scarce.