Quenching effect of cerium oxide nanoparticles on singlet oxygen: validation of the potential for reaction with multiple reactive oxygen species.

Here we studied cerium oxide nanoparticles (nanoceria) as an agent for the future treatment of oxidative damage by validating and evaluating its scavenging activity towards reactive oxygen species (ROS) . Nanoceria has been shown to mimic the activities of superoxide dismutase and catalase, degrading superoxide (O) and hydrogen peroxide (HO). We examined the antioxidative activity of nanoceria, focusing on its ability to quench singlet oxygen (O) in an aqueous solution.