Publications by authors named "Tsunemori Sakamoto"
Background: Pathological studies report that acute ST segment elevation myocardial infarction (STEMI) is caused not only by plaque rupture but also by other causes, such as erosion. To test our hypothesis that different lesion morphologies result in different clinical outcomes, we used intravascular ultrasound (IVUS) to investigate the relationship between lesion morphology and infarct size after successful primary angioplasty.
Methods: Our 72 consecutive first anterior STEMI patients underwent preintervention IVUS and were successfully recanalized with primary angioplasty.
Article Synopsis
- This study explored how the shape of ruptured plaques in coronary arteries, determined from intravascular ultrasound (IVUS) images, relates to blood flow grades during acute coronary syndrome (ACS).
- Researchers analyzed 72 ACS patients, dividing them into three groups based on where the plaque ruptured: proximal shoulder, mid-portion, and distal shoulder.
- Findings indicated that those with proximal shoulder ruptures were more likely to have no blood flow (TIMI 0) compared to the other groups, suggesting that the specific morphology of a ruptured plaque influences the likelihood of significant artery blockage in ACS.
Objectives: This study sought to investigate the relationship between multiple plaque ruptures, C-reactive protein (CRP), and clinical prognosis in acute myocardial infarction (AMI).
Background: Several studies have demonstrated that ruptured or vulnerable plaques exist not only at the culprit lesion but also in the whole coronary artery in some acute coronary syndrome (ACS) patients. Recent studies have reported that a ruptured plaque at the culprit lesion is associated with elevated CRP, which indicates a poor prognosis in patients with ACS.
Background: HMG-CoA reductase inhibitors (statin) have been reported to decrease coronary artery events in several angiographic studies. However, the mechanism by which statin achieve this is still unclear. The purpose of this study was to identify the effect of statin on coronary plaque using serial intravascular ultrasound analysis.
View Article and Find Full Text PDFStudies have reported a circadian variation in the onset of acute myocardial infarction (AMI). Pathologic studies have revealed that plaque rupture is 1 of the major causes of AMI, but none of these has looked specifically at the circadian variation of plaque rupture. The aim of this study was to use intravascular ultrasound (IVUS) to investigate the circadian variation of plaque rupture in AMI.
View Article and Find Full Text PDFArticle Synopsis
- - This study explored whether using intravascular ultrasound (IVUS) before primary angioplasty could help predict the risk of acute coronary occlusion after the procedure in patients with acute myocardial infarction (AMI).
- - Out of 46 patients, 28% experienced acute coronary occlusion post-angioplasty, with no significant differences found in overall clinical characteristics between those who experienced occlusion and those who did not.
- - The findings indicated that patients with acute occlusion had a much higher prevalence of eccentric plaques and echolucent areas, suggesting that these conditions are linked to a higher likelihood of occlusion after angioplasty, thus making IVUS a valuable tool in managing treatment strategies for AMI.