Publications by authors named "Tsunamasa Inou"
Article Synopsis
- The study explores the effects of parathyroidectomy on bone density in cortical versus cancellous bone, noting that cancellous bone shows greater changes than cortical bone.
- After parathyroidectomy, cancellous bone displayed a quick decline in osteoclast activity to 0%, while cortical bone showed a less pronounced response.
- Findings indicate that changes in bone formation markers occurred after histomorphometric changes, highlighting a delayed response in cortical bone compared to cancellous bone.
In recent years, the incidence of prostate carcinoma in patients with renal failure is increasing. But it is difficult to diagnose the occurrence of this neoplasm because of decrease of urinary volume in these patients. Two hemodialysis patients (age: 64, 68 years, the duration of hemodialysis: 10, 8 years) suffering from prostate carcinoma were treated with androgen deprivation therapy, which accelerates bone resorption.
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- The study examined how total parathyroidectomy and autotransplantation affect bone structure in patients with secondary hyperparathyroidism.
- Despite low PTH levels after 12 weeks, low turnover bone disease was observed, indicating that bone resorption still outpaced formation a year post-surgery.
- Long-term monitoring of bone mineral density is crucial due to these findings, as patients may experience significant decreases in bone density over time.
Background: Successful parathyroidectomy for secondary hyperparathyroidism alleviates bone pain and is followed by the development of hypophosphatemia and hypocalcemia, as well as an increase in bone mineral density. An increase in osteoblast surface (Ob.S/BS) is not observed several months after surgery.
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